Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection.

Autor: Vanover D; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Zurla C; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Peck HE; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Orr-Burks N; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA., Joo JY; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Murray J; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA., Holladay N; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA., Hobbs RA; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Jung Y; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Chaves LCS; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Rotolo L; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Lifland AW; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA., Olivier AK; Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Starkville, MS, 39762, USA., Li D; Duke Human Vaccine Institute and the Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Saunders KO; Duke Human Vaccine Institute, Departments of Surgery, Molecular Genetics and Microbiology, and Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Sempowski GD; Duke Human Vaccine Institute and the Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Crowe JE Jr; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Haynes BF; Duke Human Vaccine Institute and the Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC, 27710, USA., Lafontaine ER; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA., Hogan RJ; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA.; Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602, USA., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA, 30322, USA.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2022 Dec; Vol. 9 (34), pp. e2202771. Date of Electronic Publication: 2022 Oct 31.

Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection.

Autor: Tiwari PM; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA., Vanover D; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA., Lindsay KE; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA., Bawage SS; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA., Kirschman JL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA., Bhosle S; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA., Lifland AW; Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, 30332, USA., Zurla C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA. philip.santangelo@bme.gatech.edu.

Publikováno v: Nature communications [Nat Commun] 2018 Oct 01; Vol. 9 (1), pp. 3999. Date of Electronic Publication: 2018 Oct 01.

Structural analysis of respiratory syncytial virus reveals the position of M2-1 between the matrix protein and the ribonucleoprotein complex.

Autor: Kiss G; Division of Pediatric Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Holl JM; Division of Pediatric Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Williams GM; Division of Pediatric Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Alonas E; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA., Vanover D; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA., Lifland AW; Vutara, Inc., Salt Lake City, Utah, USA., Gudheti M; Vutara, Inc., Salt Lake City, Utah, USA., Guerrero-Ferreira RC; Division of Pediatric Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Nair V; Research Technologies Branch, Microscopy Unit, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA., Yi H; Robert P. Apkarian Integrated Electron Microscopy Core, Emory University, Atlanta, Georgia, USA., Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA., Wright ER; Division of Pediatric Infectious Diseases, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia, USA Robert P. Apkarian Integrated Electron Microscopy Core, Emory University, Atlanta, Georgia, USA erwrigh@emory.edu.

Publikováno v: Journal of virology [J Virol] 2014 Jul; Vol. 88 (13), pp. 7602-17. Date of Electronic Publication: 2014 Apr 23.

Characterization of mRNA-cytoskeleton interactions in situ using FMTRIP and proximity ligation.

Autor: Jung J; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, United States of America., Lifland AW, Alonas EJ, Zurla C, Santangelo PJ

Publikováno v: PloS one [PLoS One] 2013 Sep 11; Vol. 8 (9), pp. e74598. Date of Electronic Publication: 2013 Sep 11 (Print Publication: 2013).

Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS.

Autor: Lifland AW; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA., Jung J, Alonas E, Zurla C, Crowe JE Jr, Santangelo PJ

Publikováno v: Journal of virology [J Virol] 2012 Aug; Vol. 86 (15), pp. 8245-58. Date of Electronic Publication: 2012 May 23.