Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lifen Ren"'
Publikováno v:
Clinical Laboratory; 2024, Vol. 70 Issue 8, p1452-1456, 5p
Autor:
Jingying Nong, Xi Li, Deruo Liu, Quan Zhang, Jia-lin Lü, Huiyi Yang, Lifen Ren-Heidenreich, Shucai Zhang, Yi-fen Sun, Na Qin, Shanqing Li, Xinjie Yang, Yuhua Wu, Hui Zhang, Yong-Qing Zheng, Xinyong Zhang
Publikováno v:
The Journal of Molecular Diagnostics. 15:819-826
Somatic DNA mutations affecting the epidermal growth factor receptor (EGFR) signaling pathway are known to predict responsiveness to EGFR-tyrosine kinase inhibitor drugs in patients with advanced non-small-cell lung cancers. We evaluated a sensitive
Publikováno v:
cclm. 48:1103-1106
Background: Somatic mutations in the KRAS gene have been reported to confer drug resistance to epidermal growth factor receptor tyrosine kinase inhibitors and some monoclonal antibodies. However, current DNA mutation detection technologies are primar
Publikováno v:
Acta biochimica et biophysica Sinica. 46(6)
A single nucleotide polymorphism (SNP) is the most frequent type of variation in the genome. There are around 10 million SNPs that have been identified in the human genome [1]. Because SNPs are highly conserved throughout evolution and within a popul
Autor:
Susumu Suzuki, Makoto Yazaki, Masakazu Nitta, Kazuya Tsuboi, Seiji Kojima, Lifen Ren, Taiji Kato, Shinsuke Harada, Shogo Banno, Humping Ni, Hirokazu Komatsu, Ryuzo Ueda, Atsushi Wakita
Publikováno v:
Cancer Letters. 124:173-180
We studied the feasibility of the clinical application of a new bcr/abl analysis system, C-TRAK t(9;22), consisting of a multiplex RT-PCR and a colormetric assay. With this system, bcr/abl transcripts could be detected in all of 24 cytogenetic Philad
Publikováno v:
Chemico-Biological Interactions. 104:55-64
Many chemicals have recently been discovered to have estrogenic activity, including the surfactant intermediate nonylphenol (NP). It has been well documented that estrogen is a facilitator of human breast cancer development under certain conditions,
Publikováno v:
Chemico-Biological Interactions. 102:63-67
During our studies on the effects of environmental estrogenic chemicals on vitellogenin gene expression in fish, dimethyl formamide (DMFA) and ethylene glycol (EG) were used as solvents to dissolve and deliver hydrophobic β-estradiol or nonylphenol.
Publikováno v:
Chemico-Biological Interactions. 100:67-76
Estrogenic chemicals have drawn considerable attention over the past several years because they are known to be responsible for increased breast and prostate cancer [1,2]. Vitellogenin expression driven by estrogen has been becoming a model for study
Autor:
Zhangmin Liang, Jiasen Xu, Zhiping Cai, Jianping Xu, Jiaying He, Lifen Ren-Heidenreich, Xiaodi Luo, Jiaxin Chen, Huiyi Yang
Publikováno v:
Cancer biomarkers : section A of Disease markers. 10(2)
The prevalence of EGFR, KRAS, BRAF and PIK3CA somatic mutations in 861 randomly selected Chinese patients with non-small cell lung cancer (NSCLC) was assayed by the SurPlex -xTAG70plex platform and analyzed. The results showed that the occurrence rat
Autor:
Gang Yu, Guoqiang Li, Jiaying He, Tao Zeng, Jiasen Xu, Qin Huijuan, Liu Zhiming, Zeyao Zhu, Lifen Ren-Heidenreich, Xiaodi Luo, Shiyang Wu
Publikováno v:
Clinical chemistry and laboratory medicine. 49(2)
Background: DNA somatic mutations of EGFR, KRAS, BRAF and PIK3CA in the epidermal growth factor receptor (EGFR) signaling pathway play critical roles in the response or resistance of tumors to targeted therapy with tyrosine kinase inhibitors (EGFR-TK