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pro vyhledávání: '"Lifang Chan"'
Autor:
Hung Thanh Nguyen, Xin Hong, Sam Tan, Qingfeng Chen, Lifang Chan, Marc Fivaz, Stephen M. Cohen, P. Mathijs Voorhoeve
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 707-713 (2014)
Primary human cells can be transformed into tumor cells by a defined set of genetic alterations including telomerase, oncogenic RasV12, and the tumor suppressors p53 and pRb. SV40 small T (ST) is required for anchorage-independent growth in vitro and
Externí odkaz:
https://doaj.org/article/ee18232ab2bf4df9a3bb3e6eb9fad805
Autor:
Marc Fivaz, Qingfeng Chen, Xin Hong, Lifang Chan, Sam Tan, Stephen M. Cohen, Hung Thanh Nguyen, P. Mathijs Voorhoeve
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 707-713 (2014)
SummaryPrimary human cells can be transformed into tumor cells by a defined set of genetic alterations including telomerase, oncogenic RasV12, and the tumor suppressors p53 and pRb. SV40 small T (ST) is required for anchorage-independent growth in vi
Publikováno v:
Cancer Research. 73:A44-A44
Ultra conserved regions are stretches of DNA in the genome of >200bp that are 100% conserved between human, mouse and rat. Their overall conservation in a wide variety of vertebrates is often >95%. There are ~ 500 such regions in the human genome. Th