Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lifan Lin"'
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
ABSTRACT Background and aims Myofibroblasts, the primary producers of extracellular matrix, primarily originate from hepatic stellate cells (HSCs), and their activation plays a pivotal role in liver fibrosis. This study aimed to investigate the funct
Externí odkaz:
https://doaj.org/article/bdbc2e34c9fe4313bc00d6707a867085
Autor:
Xinmiao Li, Yifei Li, Weizhi Zhang, Feng Jiang, Lifan Lin, Yining Wang, Lingling Wu, Han Zeng, Jianjian Zheng
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
ABSTRACT Introduction Liver fibrosis is primarily driven by the activation of hepatic stellate cells (HSCs), which involves various epigenetic modifications. Objectives N6‐methyladenosine (m6A), the most prevalent RNA modification in eukaryotic cel
Externí odkaz:
https://doaj.org/article/c83d0cab21084294b8e5739e79df0388
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 5, Pp 100902- (2024)
Liver fibrosis is primarily driven by the activation of hepatic stellate cells (HSCs), a process associated with ferroptosis. Ginsenoside Rb1 (GRb1), a major active component extracted from Panax ginseng, inhibits HSC activation. However, the potenti
Externí odkaz:
https://doaj.org/article/ab6deddcd7d7446fa65502d7a38560e9
Autor:
Qiqi Tao, Zhichao Lang, Yifei Li, Yuxiang Gao, Lifan Lin, Zhengping Yu, Jianjian Zheng, Suhui Yu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Necroptosis has been reported to be involved in cancer progression and associated with cancer prognosis. However, the prognostic values of necroptosis-related genes (NRGs) in hepatocellular carcinoma (HCC) remain largely unknown. This study
Externí odkaz:
https://doaj.org/article/a38b2b8e1706401f83f41d8f4ecccfc3
Autor:
Zhichao Lang, Yifei Li, Lifan Lin, Xinmiao Li, Qiqi Tao, Yuhang Hu, Menglu Bao, Lei Zheng, Zhengping Yu, Jianjian Zheng
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Recently, Salidroside (Sal) has been demonstrated to suppress hepatic stellate cell (HSC) activation, a crucial event for liver fibrosis. Moreover, Sal has been reported to decrease hepatocyte injury. A growing number of reports have indicat
Externí odkaz:
https://doaj.org/article/cde14952e0f8495e9894ea1a041cb3e8
Autor:
Xiaodong Wang, Ji Chen, Lifan Lin, Yifei Li, Qiqi Tao, Zhichao Lang, Jianjian Zheng, Zhengping Yu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract As a highly heterogeneous cancer, the prognostic stratification and personalized management of hepatocellular carcinoma (HCC) are still challenging. Recently, Antigen-presenting-cells (APCs) and T-cells-infiltration (TCI) have been reported
Externí odkaz:
https://doaj.org/article/484314ba3c7e4a62ba5a7f4dd77bc360
Autor:
Yating Zhan, Qiqi Tao, Qishan Meng, Rongrong Zhang, Lifan Lin, Xinmiao Li, Lei Zheng, Jianjian Zheng
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Long non-coding RNA-myocardial infarction-associated transcript (lncRNA-MIAT) has been reported to play an important role in the development of multiple cancers. However, the biological roles of MIAT in liver fibrosis are still unknown. In t
Externí odkaz:
https://doaj.org/article/71bfb92c00fb41159696c81ccc2edb13
Autor:
Zhan Yang, Xinmiao Li, Chaoran Pan, Yifei Li, Lifan Lin, Yan Jin, Jianjian Zheng, Zhengping Yu
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Exosomes play an important role in the tumor microenvironment (TME) and the mechanisms of tumor immune escape in hepatocellular carcinoma (HCC). It is known that immunosuppressive genes, involved in the processes of tumor immunosu
Externí odkaz:
https://doaj.org/article/4bc642d062e7439ebafee8d017f81659
Autor:
Yating Zhan, Qiqi Tao, Qishan Meng, Rongrong Zhang, Lifan Lin, Xinmiao Li, Lei Zheng, Jianjian Zheng
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/eecd5b31ef59457294a05e552052e35e
Autor:
Guangyao Zhou, Chunxue Li, Rongrong Zhang, Yating Zhan, Lifan Lin, Zhichao Lang, Qiqi Tao, Jianjian Zheng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Kaempferol, a natural flavonoid molecule, has demonstrated anti-inflammatory, antimicrobial and antioxidant activities. Recent studies have shown the beneficial effects of kaempferol on liver fibrosis. Notch pathway has been reported to be involved i
Externí odkaz:
https://doaj.org/article/dee1ff1aac4e4d8a80da66bef9a3df48