Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Lieven Lagae"'
Autor:
Elaine C. Wirrell, Lieven Lagae, Ingrid E. Scheffer, J. Helen Cross, Nicola Specchio, Adam Strzelczyk
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1643-1657 (2024)
Abstract Fenfluramine (FFA), an antiseizure medication (ASM) with serotonergic and sigma‐1 receptor activity, is used to manage patients with developmental and epileptic encephalopathies (DEEs). It is approved in the US for treating seizures associ
Externí odkaz:
https://doaj.org/article/3dc1b09b0bfc46e7857e957e7df05a9b
Autor:
Indra A. Van Assche, Kristel Van Calsteren, Evangeline A. Huis in ’t Veld, Mathilde van Gerwen, Laura Heylen, Charlotte L. LeJeune, Elyce Cardonick, Michael J. Halaska, Robert Fruscio, Monica Fumagalli, Elisabeth M. van Dijk-Lokkart, Jurgen Lemiere, Martine van Grotel, Lieven Lagae, Marry M. van den Heuvel-Eibrink, Frédéric Amant
Publikováno v:
EClinicalMedicine, Vol 78, Iss , Pp 102922- (2024)
Summary: Background: Platina and taxanes are frequently used chemotherapeutic agents to treat cancer, also when diagnosed during pregnancy. This report presents an interim analysis of the largest series of children prenatally exposed to platinum and/
Externí odkaz:
https://doaj.org/article/f5c3e461287c4daeb19e9e5593f787dc
Autor:
Renee Proost, Elisabeth Heremans, Lieven Lagae, Wim Van Paesschen, Maarten De Vos, Katrien Jansen
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
ObjectivesThis study aimed to validate a sleep staging algorithm using in-hospital video-electroencephalogram (EEG) in children without epilepsy, with well-controlled epilepsy (WCE), and with drug-resistant epilepsy (DRE).MethodsOvernight video-EEG,
Externí odkaz:
https://doaj.org/article/c78dbc550f6d4172a509766e3652b52a
Autor:
Adam Strzelczyk, Lieven Lagae, Jo M Wilmshurst, Andreas Brunklaus, Pasquale Striano, Felix Rosenow, Susanne Schubert‐Bast
Publikováno v:
Epilepsia Open, Vol 8, Iss 4, Pp 1256-1270 (2023)
Abstract We performed a systematic literature review and narrative synthesis according to a pre‐registered protocol (Prospero: CRD42022376561) to identify the evidence associated with the burden of illness in Dravet syndrome (DS), a developmental a
Externí odkaz:
https://doaj.org/article/1c4d31b23fcd4896a04ebb2d52b09c6c
Autor:
Franz Huschner, Jagoda Głowacka-Walas, James D. Mills, Katarzyna Klonowska, Kathryn Lasseter, John M. Asara, Romina Moavero, Christoph Hertzberg, Bernhard Weschke, Kate Riney, Martha Feucht, Theresa Scholl, Pavel Krsek, Rima Nabbout, Anna C. Jansen, Bořivoj Petrák, Jackelien van Scheppingen, Josef Zamecnik, Anand Iyer, Jasper J. Anink, Angelika Mühlebner, Caroline Mijnsbergen, Lieven Lagae, Paolo Curatolo, Julita Borkowska, Krzysztof Sadowski, Dorota Domańska-Pakieła, Magdalena Blazejczyk, Floor E. Jansen, Stef Janson, Malgorzata Urbanska, Aleksandra Tempes, Bart Janssen, Kamil Sijko, Konrad Wojdan, Sergiusz Jozwiak, Katarzyna Kotulska, Karola Lehmann, Eleonora Aronica, Jacek Jaworski, David J. Kwiatkowski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract We present a comprehensive multi-omic analysis of the EPISTOP prospective clinical trial of early intervention with vigabatrin for pre-symptomatic epilepsy treatment in Tuberous Sclerosis Complex (TSC), in which 93 infants with TSC were foll
Externí odkaz:
https://doaj.org/article/4ebd3a42e79a421f9ec149801b6df580
Autor:
Jo Sourbron, Stéphane Auvin, Alexis Arzimanoglou, J. Helen Cross, Hans Hartmann, Ronit Pressler, Kate Riney, Kenji Sugai, Jo M. Wilmshurst, Elissa Yozawitz, Lieven Lagae
Publikováno v:
Epilepsia Open, Vol 8, Iss 1, Pp 77-89 (2023)
Abstract Objective Antiseizure medications (ASMs) remain the mainstay of epilepsy treatment. These ASMs have mainly been tested in trials in adults with epilepsy, which subsequently led to market authorization (MA). For treatment of – especially yo
Externí odkaz:
https://doaj.org/article/d7e8ed31b1b44f2d8effbe4dcf7b5c7a
Autor:
Lieven Lagae
For many parents, cognitive and behavioral comorbidities, such as ADHD, autism and intellectual disability, are the real burden of childhood epilepsy. This title offers concrete guidance and treatment strategies for childhood epilepsy in general, and
Autor:
Jo Sourbron, Lieven Lagae
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Developmental and epileptic encephalopathies are rare, treatment-resistant epilepsies with high seizure burden and non-seizure comorbidities. The antiseizure medication (ASM) fenfluramine is an effective treatment for reducing seizure frequency, amel
Externí odkaz:
https://doaj.org/article/aff4b99698f445948668628c8d783e8c
Autor:
Jo Sourbron, Lieven Lagae
Publikováno v:
Epilepsia Open, Vol 7, Iss 2, Pp 231-246 (2022)
Abstract Despite the availability of over 30 antiseizure medications (ASMs), there is no “one size fits it all,” so there is a continuing search for novel ASMs. There are divergent data demonstrating that modulation of distinct serotonin (5‐hyd
Externí odkaz:
https://doaj.org/article/ca8c88dcf51f4ef787b3f08847381e57
Autor:
Elena Cardenal‐Muñoz, Stéphane Auvin, Vicente Villanueva, J. Helen Cross, Sameer M. Zuberi, Lieven Lagae, José Ángel Aibar
Publikováno v:
Epilepsia Open, Vol 7, Iss 1, Pp 11-26 (2022)
Abstract Dravet syndrome (DS) is a severe, rare, and complex developmental and epileptic encephalopathy affecting 1 in 16 000 live births and characterized by a drug‐resistant epilepsy, cognitive, psychomotor, and language impairment, and behaviora
Externí odkaz:
https://doaj.org/article/6f738f3396a94d8e9441daf564c14571