Partnership of I-ACT for children (US) and European pediatric clinical trial networks to facilitate pediatric clinical trials

Autor: Eva Degraeuwe, Collin Hovinga, Annelies De Maré, Ricardo M. Fernandes, Callie Heaton, Lieve Nuytinck, Laura Persijn, Ann Raes, Johan Vande Walle, Mark A. Turner

Publikováno v: Frontiers in Pediatrics, Vol 12 (2024)

Background/aimsDue to a lack of standard pediatric prescribing information, medicines are often used in a dosage form or for an indication that has not been investigated in children. Pediatric clinical trial research networks aim to facilitate the ti

Externí odkaz: https://doaj.org/article/f30308b70eeb4806b9cfd55b246f4b4c

Potential of Urine Biomarkers CHI3L1, NGAL, TIMP-2, IGFBP7, and Combinations as Complementary Diagnostic Tools for Acute Kidney Injury after Pediatric Cardiac Surgery: A Prospective Cohort Study

Autor: Wim Vandenberghe, Jorien De Loor, Katrien Francois, Kristof Vandekerckhove, Ingrid Herck, Johan Vande Walle, Harlinde Peperstraete, Thierry Bové, Daniël De Wolf, Lieve Nuytinck, Jan J. De Waele, Evelyne Meyer, Eric A. J. Hoste

Publikováno v: Diagnostics, Vol 13, Iss 6, p 1047 (2023)

Acute kidney injury (AKI) is common after pediatric cardiac surgery (CS). Several urine biomarkers have been validated to detect AKI earlier. The objective of this study was to evaluate urine CHI3L1, NGAL, TIMP-2, IGFBP7, and NephroCheck® as predict

Externí odkaz: https://doaj.org/article/33c93071add545a2bc86809b66adbfb1

9 The flood of study feasibilities and the value of a centralised approach

Autor: Eva Degraeuwe, Laura Persijn, Lieve Nuytinck, Ann Raes, Mark Turner, Johan Vande Walle

Publikováno v: Archives of Disease in Childhood. 108:A3.2-A3

IntroductionDue to an increase in multicentric paediatric clinical trials after 2007 following the EU Paediatric Regulation, there has been a substantial increase in the number of feasibility questionnaires (FQ). Paediatric clinical trial conduct has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb1b9b6d663ecb7e58df374b4d127dca
https://doi.org/10.1136/archdischild-2023-esdppp.9

Evaluating risk, safety and efficacy of novel reproductive techniques and therapies through the EuroGTP II risk assessment tool

Autor: Esteve Trias, 1, Martine Nijs, 2, 3 4, Ioana Adina Rugescu, Francesco Lombardo, 5, Gueorgui Nikolov, 5, Veerle Provoost, 6, Annelies Tolpe, 7, Nathalie Vermeulen, 8, Zdravka Veleva, 9, Rita Piteira 10, Ricardo Casaroli-Marano 10, Kelly Tilleman, 7, EuroGTP II Study Group:EuroGTP II Study Group: Anna Vilarrodona, A Rita Piteira, Elba, Agustí, Elisabet, Tahull, Esteve, Trias, Eva Maria Martinez, Ivan, Miranda, Jaime, Tabera, Maria Luisa Perez, Marta, Torrabadella, Nausica, Otero, Oscar, Fariñas, Patricia, López-Chicón, Sergi, Querol, Ricardo, Casaroli, Akila, Chandrasekar, Kyle, Bennett, Paul, Rooney, Richard, Lomas, Mar, Carmona, Esteban, Molano, Myriam, Ormeño, Branka Golubić Ćepulić, Ivan, Rozman, Marijana, Dragović, Cristina, Pintus, Eliana, Porta, Fiorenza, Bariani, Letizia, Lombardini, Liliam, Santilli, Mariapia, Mariani, Paola Di Ciaccio, Silvia, Pisanu, Artur, Kamiński, Izabela, Uhrynowska-Tyszkiewicz, Ewa, Olender, Anne Marie van Walraven, Arlinke, Bokhorst, Ingrid van Veen, Kelly, Tilleman, Tolpe, Annelies, Veerle, Provoost, Lieve, Nuytinck, Maryana, Simeonova, Daniela, Staneva-Petkova, Dessislava, Tzoneva, Tsvetelina, Kircheva-Nikolova, Violetta, Marinkova, Valery, Georgiev, Yoran, Peev, Elizabeth, Manova, Cecilia, Surján, Éva, Belicza, Gábor, Szarvas, Judit, Lám, László, Bencze, Martin, Börgel, Mareike, Derks, Sibylla, Schwarz, Ramadan, Jashari, Richard, N Noumanje, Rosario Daiz Rodriguez, Tiia, Tallinen, Hanna, Kankkonen, Toni-Karri, Pakarinen, Gilbert, Verbeken, Jean-Paul, Pirnay, Thomas, Rose, Jean-Pierre, Draye, Simone, Hennerbichler, Jill, Davies, Jacinto, Ibañez, Cristina, Magli, Nathalie, Vermeulen, Monserrat, Boada, Eoin, Mcgrath, John, Armitage, Gary, Jones, Marta, Fraga, Dulce, Roldao, Josefina, Oliveira, Adolfo, Paolin, Diletta, Trojan, Giulia, Montagner, Diego, Ponzin, Stefano, Ferrari, Lombardo, Francesco, Carlijn, Voermans, Nelleke, Richters, Ioana Adina Rugescu, Gianpaolo, Azzena, Fabozzo, Assunta, Helene, Schoenmans, Jose Luis Pomar, Pablo, Gelber, Katalin, Rajczy, Boris, Calmels, Stephan, Mielke, Tanja, Netelenbos, Mirko, Ragazzo, Gueorgui, Nikolov, Marton, Elisabetta, Martine, Nijs, Antonella, Franch, Gianluca, Piovan, Francesco, Dell'Antonia, Martyn, Snow, Ines, Bojanic, Zdravka, Veleva, Grezgorz, Basak, Margarida, Amil, Sandra, Shaw, Aurora, Navarro, Tim, Spalding, Peter, Verdonk

Publikováno v: HUMAN REPRODUCTION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

STUDY QUESTIONCan risks associated with novelties in assisted reproduction technologies (ARTs) be assessed in a systematic and structured way?SUMMARY ANSWERAn ART-specific risk assessment tool has been developed to assess the risks associated with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea0401d1ea8c053a33c59df9c2b6561
https://doi.org/10.1093/humrep/deaa146

Survey by TEDDY European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe‐wide trials

Autor: Maria Grazia Felisi, Elke Gasthuys, Mark A. Turner, Franco Bartoloni, Mary Costello, Donato Bonifazi, Adriana Ceci, Lieve Nuytinck, Federico Martinon Torres, Anila Godo, Fedele Bonifazi, Francesca Rocchi, Annalisa Landi, David Nadal, Lucia Ruggieri

Publikováno v: Acta Paediatrica. 109:607-612

Aim: The European Network of Excellence for Paediatric Clinical Research, known as the TEDDY Network, carried out a survey to determine the capacity and competence of paediatric centres to perform research studies. Methods: A cross-sectional, web-bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f53fdbc63023401f52b5bd63c6dff6f
https://doi.org/10.1111/apa.15020