Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Liesl Duffy"'
Autor:
Liesl Duffy, Andrew McDonald, Tim Lambert, Sue Sacker, Michael Moore, Ian Caterson, Jeff Snars, Len Kritharides, Victor Storm, Paul Clenaghan, Janice Purvis, Sameer Bhole, Phil Escott, Angela Meaney, Robert Lusby, Ron Grunstein, Lou-Anne Blunden, Clair Edwards, Deborah Willcox, Tim Sinclair, Madeleine Kitchener, Karen Bedford, Paul Haber, Simon Cowap, Rose Meiruntu, Stephen Simpson, Nick Glozier, Leena Gupta, Teresa Anderson
Publikováno v:
International Journal of Integrated Care, Vol 14, Iss 9 (2014)
Externí odkaz:
https://doaj.org/article/5e8322825a4149a780590105cb2fc740
Publikováno v:
Neuropeptides. 44:233-239
Recent research has highlighted a potential role for neuropeptide Y (NPY) and its Y(1) receptor in the development of schizophrenia. Genetic as well as molecular biological studies have demonstrated reduced levels of NPY in schizophrenia patients. Im
Publikováno v:
Behavioural Brain Research. 207:434-440
Expression levels of neuropeptide Y (NPY) are changed in schizophrenia patients. However, the direction of changes to NPY expression and the mechanisms behind NPY's impact on the development of the illness is not understood in detail. Here we investi
Publikováno v:
European Journal of Neuroscience. 28:173-180
The abundantly expressed neuropeptide Y (NPY) plays an important role in anxiety and stress reactivity, as exogenous NPY administration reduces anxiety-like behaviour in rodents. However, unlike the potent effects of NPY seen in pharmacological studi
Publikováno v:
Journal of Neurochemistry. 105:641-652
While the regenerative capacity of the olfactory neuroepithelium has been well studied less is known about the molecular events controlling precursor cell activity. Neuropeptide Y (NPY) is expressed at high levels in the olfactory system, and NPY has
Publikováno v:
Schizophrenia Research. 99:341-349
Changes in neuregulin 1 expression have been reported in the CNS from subjects with schizophrenia. As neuregulin 1 is important in cortical development we postulated that changes in neuregulin 1 expression may contribute towards changes in cholinergi
Publikováno v:
Genes, Brain and Behavior. 6:677-687
Human genetic studies have shown that neuregulin 1 (NRG1) is a potential susceptibility gene for schizophrenia. Nrg1 influences various neurodevelopmental processes, which are potentially related to schizophrenia. The neurodevelopmental theory of sch
Autor:
Elizabeth O'Brien, Liesl Duffy, Katy Slack, Irina Dedova, Tim Karl, Nicola J. Lee, En-Ju D. Lin, Herbert Herzog, Amanda Sainsbury, Izuru Matsumoto
Publikováno v:
Neuropharmacology. 51:1129-1136
Antipsychotic drugs have been used effectively for the treatment of schizophrenia symptoms, but they are often associated with metabolic side effects such as weight gain and endocrine disruptions. To investigate the possible mechanisms of antipsychot
Publikováno v:
Brain Research. 1113:24-32
Extrapyramidal symptoms (EPS) commonly occur as side effects of antipsychotic drugs (APDs) and are most likely to arise when the occupancy of dopamine D 2 receptors in the striatum by these drugs exceeds 80%. We aimed to characterize changes in the p
Publikováno v:
Behavioural Brain Research. 171:286-294
The therapeutic properties of typical antipsychotic drugs (APDs) such as haloperidol in schizophrenia treatment are mainly associated with their ability to block dopamine D2 receptors. This blockade is accompanied by side effects such as extrapyramid