Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lieselotte S. M. Kreuk"'
Publikováno v:
eLife, Vol 11 (2022)
In allergic asthma, allergen inhalation leads to local Th2 cell activation and peribronchial inflammation. However, the mechanisms for local antigen capture and presentation remain unclear. By two-photon microscopy of the mouse lung, we established t
Externí odkaz:
https://doaj.org/article/c701738a0a0744a488f8ec55442ad8e0
Publikováno v:
Nature, vol 575, iss 7782
Nature
Nature
Nucleic acid-sensing Toll-like receptors (TLRs) are subject to complex regulation to facilitate the recognition of microbial DNA and RNA while limiting the recognition of an organism's own nucleic acids1. Failure to properly regulate these TLRs can l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa5bfccd425e8cfd49a93bc26da748d
https://doi.org/10.1038/s41586-019-1611-7
https://doi.org/10.1038/s41586-019-1611-7
Publikováno v:
eLife. 11
In allergic asthma, allergen inhalation leads to local Th2 cell activation and peribronchial inflammation. However, the mechanisms for local antigen capture and presentation remain unclear. By two-photon microscopy of the mouse lung, we established t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0bde8a0014f46c2413d812892eff5e
https://pubmed.ncbi.nlm.nih.gov/36173678
https://pubmed.ncbi.nlm.nih.gov/36173678
The aberrant activation of immune responses at barrier surfaces may lead to pathological inflammation. In allergic asthma, allergen inhalation leads to peri-bronchial inflammation and the activation of antigen-specific Th2 cells critical for disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea66babb3ccda74853e2b622e927c364
https://doi.org/10.1101/2020.09.18.247742
https://doi.org/10.1101/2020.09.18.247742
Publikováno v:
Nature
Nature, vol 575, iss 7782
Nature, vol 575, iss 7782
At least two members of the Toll-like receptor (TLR) family, TLR7 and TLR9, can recognize self-RNA and self-DNA, respectively. Despite the structural and functional similarities between these receptors, their contributions to autoimmune diseases such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0af4e0cd4f3a8ffd8489c906590d73
https://hdl.handle.net/21.11116/0000-0006-9AE6-921.11116/0000-0006-9AE8-721.11116/0000-0006-9AE9-6
https://hdl.handle.net/21.11116/0000-0006-9AE6-921.11116/0000-0006-9AE8-721.11116/0000-0006-9AE9-6
Autor:
Nicole Baumgarth, Hannah P. Savage, Leianna C Slayden, Lieselotte S. M. Kreuk, Aaron B. Kantor, Sophia Chu, Meghan A. Koch, Gregory M. Barton, Nicholas A. Lind
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
B-1a cells play an important role in mediating tissue homeostasis and protecting against infections. They are the main producers of ‘natural’ IgM, spontaneously secreted serum antibodies predominately reactive to self antigens, like phosphatidylc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdfefce35e0f47c4b32e1e29474f7cf
https://doi.org/10.7554/elife.47015
https://doi.org/10.7554/elife.47015
Autor:
Lieselotte S. M. Kreuk, Sophia Chu, Gregory M. Barton, Leianna C Slayden, Meghan A. Koch, Aaron B. Kantor, Nicole Baumgarth, Hannah P. Savage, Nicholas A. Lind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2c5076d50773f39c92f0e3a3c7b11b3
https://doi.org/10.7554/elife.47015.028
https://doi.org/10.7554/elife.47015.028
Autor:
Meghan A. Koch, Lieselotte S. M. Kreuk, Gabrielle L. Reiner, William B. Ludington, Gregory M. Barton, Eduard Ansaldo, Kyler A. Lugo, Thaddeus D. Seher, Alison G. Stanbery
Publikováno v:
Cell, vol 165, iss 4
To maintain a symbiotic relationship between the host and its resident intestinal microbiota, appropriate mucosal Tcell responses to commensal antigens must be established. Mice acquire both IgG and IgA maternally; the former has primarily been impli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08698056f0d81d377611f9bee1a1e31b
https://escholarship.org/uc/item/7nq544pn
https://escholarship.org/uc/item/7nq544pn
Publikováno v:
Trends in parasitology. 29(3)
The complement system is one of the major innate defense mechanisms Borrelia burgdorferi sensu lato has to overcome to establish an infection of mammalian hosts and to cause Lyme borreliosis in humans. Borrelia prevents complement-mediated killing du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbdccf6813ea162f10c56e9dc0db4ed
https://pubmed.ncbi.nlm.nih.gov/23298533
https://pubmed.ncbi.nlm.nih.gov/23298533