Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Lieselot Vandemeulebroucke"'
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Akademický článek
Elevated Trehalose Levels in C. elegans daf-2 Mutants Increase Stress Resistance, Not Lifespan
Autor: Madina Rasulova, Aleksandra Zečić, Jose Manuel Monje Moreno, Lieselot Vandemeulebroucke, Ineke Dhondt, Bart P. Braeckman
Publikováno v: Metabolites, Vol 11, Iss 2, p 105 (2021)
The C. elegans insulin/IGF-1 (insulin-like growth factor 1) signaling mutant daf-2 recapitulates the dauer metabolic signature—a shift towards lipid and carbohydrate accumulation—which may be linked to its longevity and stress resistance phenotyp
Externí odkaz: https://doaj.org/article/0d52cc35b614435a8074ce3f061928d5
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2
Akademický článek
FOXO/DAF-16 Activation Slows Down Turnover of the Majority of Proteins in C. elegans
Autor: Ineke Dhondt, Vladislav A. Petyuk, Huaihan Cai, Lieselot Vandemeulebroucke, Andy Vierstraete, Richard D. Smith, Geert Depuydt, Bart P. Braeckman
Publikováno v: Cell Reports, Vol 16, Iss 11, Pp 3028-3040 (2016)
Most aging hypotheses assume the accumulation of damage, resulting in gradual physiological decline and, ultimately, death. Avoiding protein damage accumulation by enhanced turnover should slow down the aging process and extend the lifespan. However,
Externí odkaz: https://doaj.org/article/19b68d92d6af46d18ff4b9ec415b5c77
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3
Axenic Culture of Caenorhabditis elegans Alters Lysosomal/Proteasomal Balance and Increases Neuropeptide Expression
Autor: Huaihan Cai, Ping Wu, Lieselot Vandemeulebroucke, Ineke Dhondt, Madina Rasulova, Andy Vierstraete, Bart P. Braeckman
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11517
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Axenically cultured C. elegans show many characteristic traits of worms subjected to dietary restriction, such as slowed development, reduced fertility, and increased stress resistance. Hence, the term axenic dietary restriction (ADR) is often applie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e135934e378f120f4935e37f6caf446c
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5
Elevated Trehalose Levels in C. elegans daf-2 Mutants Increase Stress Resistance, Not Lifespan
Autor: Aleksandra Zečić, Ineke Dhondt, Lieselot Vandemeulebroucke, Jose Manuel Monje Moreno, Madina Rasulova, Bart P. Braeckman
Publikováno v: Metabolites
Volume 11
Issue 2
METABOLITES
Metabolites, Vol 11, Iss 105, p 105 (2021)
The C. elegans insulin/IGF-1 (insulin-like growth factor 1) signaling mutant daf-2 recapitulates the dauer metabolic signature-a shift towards lipid and carbohydrate accumulation-which may be linked to its longevity and stress resistance phenotypes.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563da851dbdca8f94364e6bede00abd7
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6
FOXO/DAF-16 Activation Slows Down Turnover of the Majority of Proteins in C. elegans
Autor: Bart P. Braeckman, Vladislav A. Petyuk, Geert Depuydt, Lieselot Vandemeulebroucke, Ineke Dhondt, Huaihan Cai, Richard D. Smith, Andy Vierstraete
Publikováno v: Cell reports
Cell Reports, Vol 16, Iss 11, Pp 3028-3040 (2016)
CELL REPORTS
Summary Most aging hypotheses assume the accumulation of damage, resulting in gradual physiological decline and, ultimately, death. Avoiding protein damage accumulation by enhanced turnover should slow down the aging process and extend the lifespan.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab925847a45b0bda75a19ace176e8ab
http://europepmc.org/articles/PMC5434875
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7
CBP-1 Acts in GABAergic Neurons to Double Life Span in Axenically Cultured Caenorhabditis elegans
Autor: Huaihan Cai, Caroline Vlaeminck, Madina Rasulova, Bart P. Braeckman, Lieselot Vandemeulebroucke, Ineke Dhondt
Publikováno v: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
When cultured in axenic medium, Caenorhabditis elegans shows the largest life-span extension compared with other dietary restriction regimens. However, the underlying molecular mechanism still remains elusive. The gene cbp-1, encoding the worm orthol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81acc282a71d8d100505a0f332852859
https://pubmed.ncbi.nlm.nih.gov/29099917
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8
Life-Span Extension by Axenic Dietary Restriction Is Independent of the Mitochondrial Unfolded Protein Response and Mitohormesis in Caenorhabditis elegans
Autor: Lea Marie Meagher, Bart P. Braeckman, Huaihan Cai, Caroline Vlaeminck, Lieselot Vandemeulebroucke, Madina Rasulova, Ineke Dhondt
Publikováno v: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
In Caenorhabditis elegans, a broad range of dietary restriction regimens extend life span to different degrees by separate or partially overlapping molecular pathways. One of these regimens, axenic dietary restriction, doubles the worm’s life span
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2116499c0bd3068313ed5b275727ac
https://pubmed.ncbi.nlm.nih.gov/28329170
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