Výsledky vyhledávání - "Lieselot Houspie"

Akademický článek

Epidemiology and genetic diversity of human respiratory syncytial virus in Belgium between 2011 and 2019

Autor: Kaat Ramaekers, Els Keyaerts, Lieselot Houspie, Kurt Beuselinck, Marijke Reynders, Katrien Lagrou, Marc Van Ranst, Annabel Rector

Publikováno v: Virology Journal, Vol 21, Iss 1, Pp 1-12 (2024)

Abstract Background Human respiratory syncytial virus (HRSV) is worldwide one of the leading causes of acute respiratory tract infections in young children and the elderly population. Two distinct subtypes of HRSV (A and B) and a multitude of genotyp

Externí odkaz: https://doaj.org/article/a6c2d3dd975c40fd90f80fdf7b06acba

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Akademický článek

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

Autor: Bert Schepens, Koen Sedeyn, Liesbeth Vande Ginste, Sarah De Baets, Michael Schotsaert, Kenny Roose, Lieselot Houspie, Marc Van Ranst, Brian Gilbert, Nico van Rooijen, Walter Fiers, Pedro Piedra, Xavier Saelens

Publikováno v: EMBO Molecular Medicine, Vol 6, Iss 11, Pp 1436-1454 (2014)

Abstract Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic

Externí odkaz: https://doaj.org/article/74d0bdaddff34dda8f48cc72ca3906d4

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Akademický článek

Circulation of HRSV in Belgium: from multiple genotype circulation to prolonged circulation of predominant genotypes.

Autor: Lieselot Houspie, Philippe Lemey, Els Keyaerts, Eva Reijmen, Valentijn Vergote, Anne Vankeerberghen, Freya Vaeyens, Hans De Beenhouwer, Marc Van Ranst

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60416 (2013)

Molecular surveillance of HRSV in Belgium for 15 consecutive seasons (1996-2011) revealed a shift from a regular 3-yearly cyclic pattern, into a yearly alternating periodicity where HRSV-B is replaced by HRSV-A. Phylogenetic analysis for HRSV-A demon

Externí odkaz: https://doaj.org/article/75a7de373f7f4a66a4544f2333173d75

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Akademický článek

Genetic variability among complete human respiratory syncytial virus subgroup A genomes: bridging molecular evolutionary dynamics and epidemiology.

Autor: Lydia Tan, Philippe Lemey, Lieselot Houspie, Marco C Viveen, Nicolaas J G Jansen, Anton M van Loon, Emmanuel Wiertz, Grada M van Bleek, Darren P Martin, Frank E Coenjaerts

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e51439 (2012)

Human respiratory syncytial virus (RSV) is an important cause of severe lower respiratory tract infections in infants and the elderly. In the vast majority of cases, however, RSV infections run mild and symptoms resemble those of a common cold. The i

Externí odkaz: https://doaj.org/article/3b90b67b6cfb430d9b4234a7bffa2600

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Pathogen transcriptional profile in nasopharyngeal aspirates of children with acute respiratory tract infection

Autor: Kiyoshi F. Fukutani, Winke Van der Gucht, Lieselot Houspie, Cristiana M. Nascimento-Carvalho, Juliana R. Oliveira, Johan Van Weyenbergh, Elke Wollants, Aldina Barral, Ricardo Khouri, Tim Dierckx, Maiara L. Bouzas, Marc Van Ranst, Camila I. de Oliveira

Publikováno v: Journal of Clinical Virology

Highlights • nCounter enables detection of pathogen transcripts in NPA with low RNA input. • nCounter detects, in a single reaction, the presence of multiple pathogens in NPA. • nCounter displayed a good agreement with Real-Time PCR for RSV.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373b986ac90e7df162489a339c47a1d4
https://doi.org/10.1016/j.jcv.2015.06.005

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Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

Autor: Liesbeth Vande Ginste, Michael Schotsaert, Koen Sedeyn, Lieselot Houspie, Nico van Rooijen, Pedro A. Piedra, Walter Fiers, Xavier Saelens, Barbara Gilbert, Marc Van Ranst, Bert Schepens, Kenny Roose, Sarah De Baets

Publikováno v: Embo Molecular Medicine, 6(11), 1436-1454. Wiley-Blackwell
EMBO Molecular Medicine
Schepens, B, Sedeyn, K, Vande Ginste, L, De Baets, S, Schotsaert, M, Roose, K, Houspie, L, Van Ranst, M, Gilbert, B, van Rooijen, N, Fiers, W, Piedra, P & Saelens, X 2014, ' Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein ', Embo Molecular Medicine, vol. 6, no. 11, pp. 1436-1454 . https://doi.org/10.15252/emmm.201404005
EMBO MOLECULAR MEDICINE

Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800f1ad2d6ddbc03875cad36fa674ea1
https://research.vumc.nl/en/publications/c54208a3-1819-42ad-9036-12a9ef6c40e7

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Comparison of the FilmArray RP, Verigene RV+, and Prodesse ProFLU+/FAST+ multiplex platforms for detection of influenza viruses in clinical samples from the 2011-2012 influenza season in Belgium

Autor: Hanne Meeuws, Lieven J. Stuyver, Marc Van Ranst, Kristiane Schmidt, Gabriela Ispas, Lieselot Houspie, Liesbeth Van Wesenbeeck, Andrea Van Immerseel

Publikováno v: Journal of Clinical Microbiology

Respiratory tract infections (RTIs) are caused by a plethora of viral and bacterial pathogens. In particular, lower RTIs are a leading cause of hospitalization and mortality. Timely detection of the infecting respiratory pathogens is crucial to optim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21258e5f3d0520f58b0d4cd0ffa1187
https://pubmed.ncbi.nlm.nih.gov/23824777

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In vivo evaluation of antiviral compounds on respiratory syncytial virus using a juvenile vervet monkey (Chlorocebus pygerythrus) infection model

Autor: Lieselot, Houspie, Hans, Stevens, Maina, Ngotho, Els, Keyaerts, Gabriela, Ispas, René, Verloes, Marc, Van Ranst, Piet, Maes

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1030

Several animal models with varying susceptibilities to respiratory syncytial virus (RSV) infection have been developed to study the specific aspects of RSV disease. Many of these models are used for testing antiviral compounds or in vaccine efficacy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::66adff48bbdafef02169f0a17e03765d
https://pubmed.ncbi.nlm.nih.gov/23821283

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The comparative genomics of human respiratory syncytial virus subgroups A and B: genetic variability and molecular evolutionary dynamics

Autor: Darren P. Martin, Lydia Tan, Grada M. van Bleek, Emmanuel J. H. J. Wiertz, Marco C. Viveen, Frank E. J. Coenjaerts, Lieselot Houspie, Philippe Lemey

Publikováno v: Journal of virology. 87(14)

Genomic variation and related evolutionary dynamics of human respiratory syncytial virus (RSV), a common causative agent of severe lower respiratory tract infections, may affect its transmission behavior. RSV evolutionary patterns are likely to be in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e688aa51811ab9421ef386a9cc763d
https://pubmed.ncbi.nlm.nih.gov/23698290

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