Výsledky vyhledávání - "Liesbet Thijs"

Akademický článek

Importance of adapted digestion conditions to simulate in vitro lipid digestion of broilers in different life stages

Autor: Daphne Michels, Sarah H.E. Verkempinck, Agnese Panozzo, Karen Vermeulen, Marc E. Hendrickx, Liesbet Thijs, Tara Grauwet

Publikováno v: Animal Nutrition, Vol 12, Iss , Pp 151-158 (2023)

In vitro digestion studies demonstrate large potential to gain more and quicker insights into the underlying mechanisms of feed additives, allowing the optimization of feed design. Unfortunately, current in vitro digestion models relevant for broiler

Externí odkaz: https://doaj.org/article/56682a6b179a4174bd5de9747f03d9ca

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The heme pocket of the globin domain of the globin-coupled sensor of Geobacter sulfurreducens--an EPR study

Autor: Sylvia Dewilde, Graham Smith, Hassane El Mkami, Sabine Van Doorslaer, Filip Desmet, Liesbet Thijs, L. Moens

Publikováno v: Journal of inorganic biochemistry

The globin-coupled sensor (GCS) of Geobacter sulfurreducens is unique amongst GCSs in that its signalling domain is a transmembrane domain with yet unknown function. In the present work we use X-band continuous-wave and pulsed electron paramagnetic r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9dab8b4eb9beccb90c3580dfb27626
https://pubmed.ncbi.nlm.nih.gov/20605218

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HisE11 and HisF8 provide bis-histidyl heme hexa-coordination in the globin domain of Geobacter sulfurreducens globin-coupled sensor

Autor: Paolo Ascenzi, Martino Bolognesi, Louise J. Gourlay, Marco Nardini, Alessandro Bolli, Liesbet Thijs, Lorenza Sisinni, Alessandra Pesce, Filip Desmet, Maqsudul Alam, Sylvia Dewilde, Xuehua Wan, L. Moens, M. Coletta, Sabine Van Doorslaer

Publikováno v: Journal of molecular biology

Among heme-based sensors, recent phylogenomic and sequence analyses have identified 34 globin coupled sensors (GCS), to which an aerotactic or gene-regulating function has been tentatively ascribed. Here, the structural and biochemical characterizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19649f727d2d287b7129bde52f9e1ed
http://hdl.handle.net/11567/231325

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Archaeal protoglobin structure indicates new ligand diffusion paths and modulation of haem-reactivity

Autor: Marco Nardini, Liesbet Thijs, Martino Bolognesi, Paolo Ascenzi, Alessandra Pesce, Maqsudul Alam, Sylvia Dewilde, Jennifer A. Saito, L. Moens, M. Coletta, Chiara Ciaccio

Publikováno v: EMBO reports
9 (2008): 157–163.
info:cnr-pdr/source/autori:Nardini, M; Pesce, A; Thijs, L; Saito, JA; Dewilde, S; Alam, M; Ascenzi, P; Coletta, M; Ciaccio, C; Moens, L; Bolognesi, M/titolo:Archaeal protoglobin structure indicates new ligand diffusion paths and modulation of haem-reactivity/doi:/rivista:EMBO reports (Print)/anno:2008/pagina_da:157/pagina_a:163/intervallo_pagine:157–163/volume:9

The structural adaptability of the globin fold has been highlighted by the recent discovery of the 2-on-2 haemoglobins, of neuroglobin and cytoglobin. Protoglobin from Methanosarcina acetivorans C2A - a strictly anaerobic methanogenic Archaea - is, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bae932ed67a783af5ec11c45376627
http://hdl.handle.net/2108/41168

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Neuroglobin and cytoglobin expression in mice. Evidence for a correlation with reactive oxygen species scavenging

Autor: Sylvia Dewilde, Liesbet Thijs, Elke Fordel, L. Moens

Publikováno v: The FEBS journal

Although essentially unknown, several functions are hypothesized for neuroglobin and cytoglobin, two new members of the globin family. In this article, we try to shed more light on their possible roles in hypoxia and detoxification of reactive oxygen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7e32aea8210ef26833fc129c007615
https://pubmed.ncbi.nlm.nih.gov/17286577

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Characterization of a globin-coupled oxygen sensor with a gene-regulating function

Autor: Evi Vinck, Paolo Ascenzi, Alessandro Bolli, Roy E. Weber, Sylvia Dewilde, Angela Fago, Liesbet Thijs, Sabine Van Doorslaer, David Hoogewijs, Massimiliano Coletta, Maqsudul Alam, Xuehua Wan, Florin Trandafir, L. Moens

Publikováno v: Thijs, L, Vinck, E, Bolli, A, Trandafir, F, Wan, X, Hoogewijs, D, Coletta, M, Fago, A, Weber, R E, Doorslaer, S V, Ascenzi, P, Alam, M, Moens, L & Dewilde, S 2007, ' Characterization of a globin-coupled oxygen sensor with a gene-regulating function ', Journal of Biological Chemistry, vol. 282, no. 52, pp. 37325-37340 . https://doi.org/10.1074/jbc.M705541200
Journal of biological chemistry

Globin-coupled sensors (GCSs) are multiple-domain transducers, consisting of a regulatory globin-like heme-binding domain and a linked transducer domain(s). GCSs have been described in both Archaea and bacteria. They are generally assumed to bind O2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69783c6244eb2119ad5bb7cdecdc0cef
https://pure.au.dk/portal/da/publications/characterization-of-a-globincoupled-oxygen-sensor-with-a-generegulating-function(ed8fe5c0-ca74-11dc-abe4-000ea68e967b).html

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Anoxia or oxygen and glucose deprivation in SH-SY5Y cells: a step closer to the unraveling of neuroglobin and cytoglobin functions

Autor: Liesbet Thijs, Wim Martinet, Dorien M. Schrijvers, Luc Moens, Sylvia Dewilde, Elke Fordel

Publikováno v: Gene

Several studies support the hypothesis that neuroglobin and cytoglobin play a protective role against cell death when cellular oxygen supply is critical. Although the underlying molecular mechanisms are unknown, previous reports suggest that this pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618fa3e1d204d4439d434088e43394d6
https://pubmed.ncbi.nlm.nih.gov/17532579

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Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death

Autor: Dirk R. Van Bockstaele, Liesbet Thijs, Marc Lenjou, Tilmann Laufs, Luc Moens, Sylvia Dewilde, Elke Fordel, Wim Martinet

Publikováno v: Neuroscience letters

Although reactive oxygen species (ROS) at physiological concentrations are required for normal cell function, excessive production of ROS is detrimental to cells. Neuroglobin and cytoglobin are two globins, whose functions are still a matter of debat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b74262dccf80013e3d13ade76d61f9c
https://hdl.handle.net/10067/603580151162165141

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