Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Liesbet Geris"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2453-2464 (2024)
The kinetics of the protein elongation cycle by the ribosome depends on intertwined factors. One of these factors is the electrostatic interaction of the nascent protein with the ribosome exit tunnel. In this computational biology theoretical study,
Externí odkaz:
https://doaj.org/article/724f2b0efb594b5aa4ac512751a11362
Autor:
Ehsan Sadeghian Dehkord, Bruno De Carvalho, Marie Ernst, Adelin Albert, France Lambert, Liesbet Geris
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101100- (2024)
Objectives: Calcium phosphate-based biomaterials (CaP) are the most widely used biomaterials to enhance bone regeneration in the treatment of alveolar bone deficiencies, cranio-maxillofacial and periodontal infrabony defects, with positive preclinica
Externí odkaz:
https://doaj.org/article/b4ab42235de2409f8b2f77335af906bb
Autor:
Katherine B. Crump, Ahmad Alminnawi, Paola Bermudez‐Lekerika, Roger Compte, Francesco Gualdi, Terence McSweeney, Estefano Muñoz‐Moya, Andrea Nüesch, Liesbet Geris, Stefan Dudli, Jaro Karppinen, Jérôme Noailly, Christine Le Maitre, Benjamin Gantenbein
Publikováno v:
JOR Spine, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract The cartilaginous endplates (CEP) are key components of the intervertebral disc (IVD) necessary for sustaining the nutrition of the disc while distributing mechanical loads and preventing the disc from bulging into the adjacent vertebral bod
Externí odkaz:
https://doaj.org/article/5b4478ce19fc4886978a62ecc9211dac
Autor:
Edoardo Borgiani, Gabriele Nasello, Liesbeth Ory, Tim Herpelinck, Lisanne Groeneveldt, Christian H. Bucher, Katharina Schmidt-Bleek, Liesbet Geris
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bone fracture healing is a well-orchestrated but complex process that involves numerous regulations at different scales. This complexity becomes particularly evident during the inflammatory stage, as immune cells invade the healing region and trigger
Externí odkaz:
https://doaj.org/article/5e0252e1af884dfbacc52a35256b0162
Autor:
Mehdi Salar Amoli, Resmi Anand, Mostafa EzEldeen, Liesbet Geris, Reinhilde Jacobs, Veerle Bloemen
Publikováno v:
Gels, Vol 10, Iss 2, p 140 (2024)
While available treatments have addressed a variety of complications in the dentoalveolar region, associated challenges have resulted in exploration of tissue engineering techniques. Often, scaffold biomaterials with specific properties are required
Externí odkaz:
https://doaj.org/article/55f74d4fb5734f28bc59ba1aa26d7fc6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3768-3795 (2023)
The central function of the large subunit of the ribosome is to catalyze peptide bond formation. This biochemical reaction is conducted at the peptidyl transferase center (PTC). Experimental evidence shows that the catalytic activity is affected by t
Externí odkaz:
https://doaj.org/article/edc77a47b63d45179c2a014bca29d8b4
An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis
Autor:
Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch, Liesbet Geris
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-25 (2022)
Abstract Background Without the availability of disease-modifying drugs, there is an unmet therapeutic need for osteoarthritic patients. During osteoarthritis, the homeostasis of articular chondrocytes is dysregulated and a phenotypical transition ca
Externí odkaz:
https://doaj.org/article/2fb86faad3ea4fd497c909d3f48ce2c2
Autor:
Niki Loverdou, Maxim Cuvelier, Gabriella Nilsson Hall, An‐Sofie Christiaens, Isaak Decoene, Kristel Bernaerts, Bart Smeets, Herman Ramon, Frank P. Luyten, Liesbet Geris, Ioannis Papantoniou
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Cartilage microtissues are promising tissue modules for bottom up biofabrication of implants leading to bone defect regeneration. Hitherto, most of the protocols for the development of these cartilaginous microtissues have been carried out i
Externí odkaz:
https://doaj.org/article/9f08099a700446d4b6e19b34041ce55d
Autor:
Bingbing Liang, Ehsan Sadeghian Dehkord, Dorien Van Hede, Mojtaba Barzegari, Bruno Verlée, Justine Pirson, Grégory Nolens, France Lambert, Liesbet Geris
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 12, p 563 (2023)
In biomaterial-based bone tissue engineering, optimizing scaffold structure and composition remains an active field of research. Additive manufacturing has enabled the production of custom designs in a variety of materials. This study aims to improve
Externí odkaz:
https://doaj.org/article/0da639fdfd304929a77c5dc5965d825e
Publikováno v:
Virtual and Physical Prototyping, Vol 17, Iss 3, Pp 682-699 (2022)
Advances in additive manufacturing technologies are leading to an increased interest in the design of intricate 3D geometries for applications ranging from aerospace to biomedical engineering. In this paper, we present ASLI (A Simple Lattice Infiller
Externí odkaz:
https://doaj.org/article/2d7018e50b1e4baebd93becb7ce5bcd9