Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lies-Anne A. Severijnen"'
Autor:
H. Jürgen Wenzel, Karl D. Murray, Saif N. Haify, Michael R. Hunsaker, Jared J. Schwartzer, Kyoungmi Kim, Albert R. La Spada, Bryce L. Sopher, Paul J. Hagerman, Christopher Raske, Lies-Anne W.F.M. Severijnen, Rob Willemsen, Renate K. Hukema, Robert F. Berman
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-22 (2019)
Abstract The fragile X premutation is a CGG trinucleotide repeat expansion between 55 and 200 repeats in the 5′-untranslated region of the fragile X mental retardation 1 (FMR1) gene. Human carriers of the premutation allele are at risk of developin
Externí odkaz:
https://doaj.org/article/4134f0078ae64270bd17af8e8378a6cd
Autor:
Fernando Cid-Samper, Mariona Gelabert-Baldrich, Benjamin Lang, Nieves Lorenzo-Gotor, Riccardo Delli Ponti, Lies-Anne W.F.M. Severijnen, Benedetta Bolognesi, Ellen Gelpi, Renate K. Hukema, Teresa Botta-Orfila, Gian Gaetano Tartaglia
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3422-3434.e7 (2018)
Summary: Recent evidence indicates that specific RNAs promote the formation of ribonucleoprotein condensates by acting as scaffolds for RNA-binding proteins (RBPs). We systematically investigated RNA-RBP interaction networks to understand ribonucleop
Externí odkaz:
https://doaj.org/article/a315cd43ede34772b46e8518544ba7c0
Autor:
Ben A. Oostra, Laura L. Kirkpatrick, Marianne Hoogeveen-Westerveld, Lies-Anne A. Severijnen, Ruben H. Willemsen, T. Zu, David L. Nelson, Ingeborg M. Nieuwenhuizen, Edwin Mientjes, Maria Rife
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 3, Pp 549-555 (2006)
Neurobiology of Disease, 21(3), 549-555. Academic Press
Neurobiology of Disease, 21(3), 549-555. Academic Press
The FMR1 gene, mutated in Fragile X syndrome patients, has been modeled in mice with a neomycin cassette inserted in exon 5 of the mouse Fmr1 gene creating an Fmr1 knockout (Fmr1 KO) allele. This results in animals lacking Fmr1 protein (Fmrp) express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996e7d6c9e5def9f50d041480af0d8bd
https://doi.org/10.1016/j.nbd.2005.08.019
https://doi.org/10.1016/j.nbd.2005.08.019
Autor:
Herma Zondervan-van der Linde, Lies-Anne A. Severijnen, Rob Willemsen, Ben A. Oostra, Tianna Zhao, Vincenzo Bonifati
Publikováno v:
PLoS One (print), 7(11). Public Library of Science
PLoS ONE, Vol 7, Iss 11, p e48911 (2012)
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e48911 (2012)
PLoS ONE
Recessive mutations in the F-box only protein 7 gene (FBXO7) cause PARK15, a mendelian form of early-onset, levodopa-responsive parkinsonism with severe loss of nigrostriatal dopaminergic neurons. However, the function of the protein encoded by FBXO7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3897fe326e74dd3cf83e665fef033763
https://pure.eur.nl/en/publications/fa515b4f-d7e1-47f8-90a3-354f8d3722e4
https://pure.eur.nl/en/publications/fa515b4f-d7e1-47f8-90a3-354f8d3722e4
Autor:
Judith R. Brouwer, David L. Nelson, Lies-Anne A. Severijnen, Cathy E. Bakker, Edwin Mientjes, Ben A. Oostra, Ingeborg M. Nieuwenhuizen, H.C. Van der Linde, Ruben H. Willemsen
Publikováno v:
Experimental Cell Research, 313(2), 244-253. Elsevier Inc.
The human FMR1 gene contains a CGG repeat in its 5' untranslated region. The repeat length in the normal population is polymorphic (5-55 CGG repeats). Lengths beyond 200 CGGs (full mutation) result in the absence of the FMR1 gene product, FMRP, throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19343edcb2a7765cb0b31f4efdf746cc
https://pubmed.ncbi.nlm.nih.gov/17150213
https://pubmed.ncbi.nlm.nih.gov/17150213
Autor:
Joost P.J.J. Hegmans, Sjaak Burgers, Jan P. van Meerbeeck, Theo M. Luider, Martin P. L. Bard, Annabrita Hemmes, Bart N. Lambrecht, Rob Willemsen, Henk C. Hoogsteden, Lies-Anne A. Severijnen
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology, 31, 114-121. American Thoracic Society
Exosomes are membrane vesicles from endosomal origin secreted by various cells such as hematopoietic, epithelial, and tumor cells. Exosomes secreted by tumor cells contain specific antigens potentially useful for immunotherapeutic purposes. Our aim w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a608a6fff93d79757b638f17c24ad8a9
https://pure.eur.nl/en/publications/a788f3f8-720f-4ad0-8725-bef3f88894cb
https://pure.eur.nl/en/publications/a788f3f8-720f-4ad0-8725-bef3f88894cb
