Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Liene, Patetko"'
Autor:
Anna Ramata-Stunda, Martins Boroduskis, Laura Pastare, Marta Berga, Liene Kienkas, Liene Patetko, Gundars Skudrins, Dace Reihmane, Ilva Nakurte
Publikováno v:
Plants, Vol 13, Iss 2, p 287 (2024)
For skin health promotion and cosmetic applications, combinations of plant cell extracts are extensively utilized. As most natural ingredient suppliers offer crude extracts from individual plants or specific isolated compounds, the potential interact
Externí odkaz:
https://doaj.org/article/1d8d3396e8c6480c9d387d399703f6ec
Autor:
Zane Simsone, Tālivaldis Freivalds, Dina Bēma, Indra Miķelsone, Liene Patetko, Juris Bērziņš, Līga Harju, Indulis Buiķis
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Background Cancer remains one of the leading causes of death worldwide, despite the possibilities to detect early onset of the most common cancer types. The search for the optimal therapy is complicated by the cancer diversity within tumors
Externí odkaz:
https://doaj.org/article/6d70df0f04734439ba41a0f1c940408c
Autor:
Ilona Pavlovska, Anna Ramata-Stunda, Zanna Martinsone, Martins Boroduskis, Liene Patetko, Inese Martinsone, Anita Seile, Ivars Vanadzins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Inhalation is the main route of exposure to airborne pollutants. To evaluate the safety and assess the risks of occupational hazards different testing approaches are used. 3D airway epithelial tissues allow to mimic exposure conditions in vi
Externí odkaz:
https://doaj.org/article/a91942dcf4824045b4cb3376665ed647
Autor:
Anna Ramata-Stunda, Martins Boroduskis, Elza Kaktina, Liene Patetko, Uldis Kalnenieks, Zane Lasa, Marta Rubina, Inese Strazdina, Gints Kalnins, Reinis Rutkis
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 551 (2023)
Skin and soft tissue infections (SSTIs) and acne are among the most common skin conditions in primary care. SSTIs caused by ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aer
Externí odkaz:
https://doaj.org/article/c4bd1d6b9ef94bebad72932897c40754
Autor:
Olga Bobileva, Raitis Bobrovs, Evelina Elva Sirma, Iveta Kanepe, Anna L. Bula, Liene Patetko, Anna Ramata-Stunda, Solveiga Grinberga, Aigars Jirgensons, Kristaps Jaudzems
Publikováno v:
Molecules, Vol 28, Iss 2, p 768 (2023)
SARS-CoV-2 nsp14 guanine-N7-methyltransferase plays an important role in the viral RNA translation process by catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to viral mRNA cap. We report a structure-guided design and synthe
Externí odkaz:
https://doaj.org/article/c2d883e7fced4f05944731ebf536ab50
Autor:
Raitis Bobrovs, Iveta Kanepe, Nauris Narvaiss, Liene Patetko, Gints Kalnins, Mihails Sisovs, Anna L. Bula, Solveiga Grinberga, Martins Boroduskis, Anna Ramata-Stunda, Nils Rostoks, Aigars Jirgensons, Kaspars Tars, Kristaps Jaudzems
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1243 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses mRNA capping to evade the human immune system. The cap formation is performed by the SARS-CoV-2 mRNA cap methyltransferases (MTases) nsp14 and nsp16, which are emerging targets for
Externí odkaz:
https://doaj.org/article/6709c629556e44969006c3d0b961d7b0
Autor:
Valdis Goncars, Eriks Jakobsons, Kristaps Blums, Ieva Briede, Liene Patetko, Kristaps Erglis, Martins Erglis, Konstantins Kalnberzs, Indrikis Muiznieks, Andrejs Erglis
Publikováno v:
Medicina, Vol 53, Iss 2, Pp 101-108 (2017)
Objective: The aim of this study was to compare treatment methods of the knee joint degenerative osteoarthritis, using autologous bone marrow-derived mononuclear cells and hyaluronic acid injections and observe prevalence of adverse effects in both g
Externí odkaz:
https://doaj.org/article/5970801c99a44ef2af2e90ba4f11cb41
Autor:
Ma̅rtiņš Borodušķis, Anna Ramata-Stunda, Liene Patetko, Gints Kalniņš, Aigars Jirgensons, M. Sisovs, Kristaps Jaudzems, Kaspars Tars, Nils Rostoks, Olga Bobiļeva, Solveiga Grinberga, Raitis Bobrovs, Iveta Kaņepe, Anna L. Bula
Publikováno v:
ACS Medicinal Chemistry Letters
Viral mRNA cap methyltransferases (MTases) are emerging targets for the development of broad-spectrum antiviral agents. In this work, we designed potential SARS-CoV-2 MTase Nsp14 and Nsp16 inhibitors by using bioisosteric substitution of the sulfoniu
Autor:
Uldis Strazdiņš, Māra Ērgle, Anna Ramata-Stunda, Silvesters Rubīns, Eva Strīķe, Simona Tīcmane, Liene Patetko, Mārtiņš Ērglis, Ēriks Jakobsons, Andrejs Ērglis, Ilze Blāķe, Beatrise Lūcija Rupaine, Andris Rubīns, Kristaps Ērglis
Publikováno v:
Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.. 74:12-17
The most common reasons for major skin loss are thermal trauma — burns and scalds that can result in rapid, extensive, deep wounds as well as chronic non-healing wounds. Treatment using common techniques is poor and depending on the trauma level ca
Autor:
Indulis Buiķis, Dina. Bēma, Juris Bērziņš, Indra Miķelsone, Zane Simsone, Līga Harju, Liene Patetko, Tālivaldis Freivalds
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-15 (2021)
BMC Cancer
BMC Cancer
Background Cancer remains one of the leading causes of death worldwide, despite the possibilities to detect early onset of the most common cancer types. The search for the optimal therapy is complicated by the cancer diversity within tumors and the u