Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Lien Ngo"'
1
Akademický článek
Development of a Pharmacokinetic Model Describing Neonatal Fc Receptor‐Mediated Recycling of HL2351, a Novel Hybrid Fc‐Fused Interleukin‐1 Receptor Antagonist, to Optimize Dosage Regimen
Autor: Lien Ngo, Jaeseong Oh, Anhye Kim, Hyun‐moon Back, Won‐ho Kang, Jung‐woo Chae, Hwi‐yeol Yun, Howard Lee
Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 10, Pp 584-595 (2020)
HL2351 (hIL‐1Ra‐hyFc) is a novel recombinant protein formed by the fusion of two human interleukin‐1 receptor antagonist components into one antibody‐derived fragment crystallizable portion. Although HL2351 has a pharmacological mechanism of
Externí odkaz: https://doaj.org/article/42fafae2b10f4a889c0303af517dd643
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5
Application of an Inter-Species Extrapolation Method for the Prediction of Drug Interactions between Propolis and Duloxetine in Humans
Autor: Wonku Kang, Keumhan Noh, Thi Lien Ngo, Su-jin Rhee, Jung-woo Chae, Chung-Hee Lee, Hyun-moon Back, Hwi-yeol Yun, Nayoung Han
Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 5
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1862 (2020)
Duloxetine (DLX) is a potent drug investigated for the treatment of depression and urinary incontinence. DLX is extensively metabolized in the liver by two P450 isozymes, CYP2D6 and CYP1A2. Propolis (PPL) is one of the popular functional foods known
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2a89b64363b4041be1054879874f3b
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7
Bioequivalence of a fixed-dose repaglinide/metformin combination tablet and equivalent doses of repaglinide and metformin tablets
Autor: Hea-Young Cho, Yoon Ho Choi, Lien Ngo, Sang-Ki Kim, Yong-Bok Lee
Publikováno v: Int. Journal of Clinical Pharmacology and Therapeutics. 56:292-300
Objective This study was conducted to determine whether a fixed-dose combination (FDC) tablet of repaglinide/metformin (2/500 mg) is equivalent to coadministration of equivalent doses of individual (EDI) tablets of repaglinide (2 mg) and metformin (5
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778bd8cfe863672a548bbd6cc3b7d476
https://doi.org/10.5414/cp203199
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8
Effects of hydrochlorothiazide and amlodipine on single oral dose pharmacokinetics of valsartan in healthy Korean subjects: Population model-based approach
Autor: Hea-Young Cho, Yong-Bok Lee, Lien Ngo
Publikováno v: European Journal of Pharmaceutical Sciences. 118:154-164
Fixed dose combination (FDC) of valsartan (VAL) and hydrochlorothiazide (HCT) or VAL and amlodipine (AML) has been available in many countries for the treatment of hypertension. Due to drug-drug interaction potentials, in the current study we aimed t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f05a117e45a28e7504612e6c5989a83
https://doi.org/10.1016/j.ejps.2018.03.031
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9
Akademický článek
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10
Population pharmacokinetic analysis of rebamipide in healthy Korean subjects with the characterization of atypical complex absorption kinetics
Autor: Yong-Bok Lee, Hea-Young Cho, Hee-Doo Yoo, Lien Ngo, Phuong H.L. Tran
Publikováno v: Journal of Pharmacokinetics and Pharmacodynamics. 44:291-303
In this study, the population pharmacokinetic (PK) analysis of rebamipide (Reba) in healthy male Korean subjects was analyzed using the nonlinear mixed effects modeling method. The possible effects of physiological covariates and the multidrug resist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f15962dd2f2f1b0fc08595231723f5
https://doi.org/10.1007/s10928-017-9519-z
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