Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Lien B, Lai"'
Autor:
Victor Chinomso Ujor, Lien B. Lai, Christopher Chukwudi Okonkwo, Venkat Gopalan, Thaddeus Chukwuemeka Ezeji
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Carbon catabolite repression (CCR) limits microbial utilization of lignocellulose-derived pentoses. To relieve CCR in Clostridium beijerinckii NCIMB 8052, we sought to downregulate catabolite control protein A (CcpA) using the M1GS ribozyme technolog
Externí odkaz:
https://doaj.org/article/990cec9e0205475d8ae352ae120b625a
Autor:
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-François Côté
Distinct functions mediated by members of the monopolar spindle-one-binder (MOB) family of proteins remain elusive beyond the evolutionary conserved and well-established roles of MOB1A and B in regulating the Hippo pathway. Since MOB proteins are ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1545aa2a35871471899949c21b0ec694
https://doi.org/10.1101/2023.05.11.540416
https://doi.org/10.1101/2023.05.11.540416
Autor:
Gable M. Wadsworth, Walter J. Zahurancik, Xiangze Zeng, Paul Pullara, Lien B. Lai, Vaishnavi Sidharthan, Rohit V. Pappu, Venkat Gopalan, Priya R. Banerjee
Co-phase separation of RNAs and RNA-binding proteins is thought to drive the biogenesis of ribonucleoprotein granules. RNAs can also undergo phase transitions in the absence of proteins. However, the physicochemical driving forces of protein-free, RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa457a23ade4c63df7f94236d31cbe57
https://doi.org/10.1101/2022.10.17.512593
https://doi.org/10.1101/2022.10.17.512593
Autor:
Lien B. Lai, Wende Liu, Venkat Gopalan, Houxiang Kang, Wei Li, Guo-Liang Wang, Liangying Dai, Yehui Xiong, Zhiqiang Li, Kai Zhang
Publikováno v:
Plant Biotechnology Journal
Summary RNase P functions either as a catalytic ribonucleoprotein (RNP) or as an RNA‐free polypeptide to catalyse RNA processing, primarily tRNA 5′ maturation. To the growing evidence of non‐canonical roles for RNase P RNP subunits including re
Autor:
Lien B. Lai, Stella M. Lai, Eric S. Szymanski, Mridu Kapur, Edric K. Choi, Hashim M. Al-Hashimi, Susan L. Ackerman, Venkat Gopalan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 10
Significance Understanding and treating neurological disorders are global priorities. Some of these diseases are engendered by mutations that cause defects in the cellular synthesis of transfer RNAs (tRNAs), which function as adapter molecules that t
Publikováno v:
Trends Biochem Sci
RNase P is an essential enzyme that catalyzes removal of the 5′ leader from precursor transfer RNAs. The ribonucleoprotein (RNP) form of RNase P is present in all domains of life and comprises a single catalytic RNA (ribozyme) and a variable number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0754f21edd3c4b7e4774623b5d5aad
https://europepmc.org/articles/PMC8595784/
https://europepmc.org/articles/PMC8595784/
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004893 (2015)
Ribonuclease P (RNase P) is an essential enzyme required for 5'-maturation of tRNA. While an RNA-free, protein-based form of RNase P exists in eukaryotes, the ribonucleoprotein (RNP) form is found in all domains of life. The catalytic component of th
Externí odkaz:
https://doaj.org/article/6f749278d895493495c13ff5dd0ef7a6
Autor:
Christopher Chukwudi Okonkwo, Thaddeus Chukwuemeka Ezeji, Lien B. Lai, Venkat Gopalan, Victor Ujor
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Carbon catabolite repression (CCR) limits microbial utilization of lignocellulose-derived pentoses. To relieve CCR in Clostridium beijerinckii NCIMB 8052, we sought to downregulate catabolite control protein A (CcpA) using the M1GS ribozyme technolog
Publikováno v:
Biochemistry
Publikováno v:
Nature Communications
RNase MRP is an essential eukaryotic ribonucleoprotein complex involved in the maturation of rRNA and the regulation of the cell cycle. RNase MRP is related to the ribozyme-based RNase P, but it has evolved to have distinct cellular roles. We report