Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lieming X"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In liver fibrosis, transforming growth factor-β1 (TGF-β1) can stimulate autophagy and activation of hepatic stellate cells (HSCs). Autophagy, playing a crucial role in HSCs activation, is related to liver fibrosis. Increasing evidence have suggeste
Externí odkaz:
https://doaj.org/article/03bdd2a5fba04ffab50156f4c32a41ce
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Sphingosine kinase 1 (SphK1)/Sphingosine-1-phosphate (S1P)/S1PRs signaling pathway is known to involve the advancement of liver fibrosis. Exosomal SphK1 promotes hepatic stellate cells (HSC) migration. Salidroside (Sal) inhibits liver fibrosis, but i
Externí odkaz:
https://doaj.org/article/15521c00e5e44efaba081f1110003775
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Various isoforms of myocyte enhancer factor 2 (MEF2) have been shown to play a role in the activation of rat hepatic stellate cells (HSCs) in culture. The signals that regulate MEF2 in HSCs are unknown. In addition, whether MEF2s regulate the activat
Externí odkaz:
https://doaj.org/article/5160beedff2247c19ff44e4bcd36ff8e
Autor:
Ralf Weiskirchen, Jörg Weimer, Steffen K Meurer, Anja Kron, Barbara Seipel, Inga Vater, Norbert Arnold, Reiner Siebert, Lieming Xu, Scott L Friedman, Carsten Bergmann
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75692 (2013)
The human hepatic cell line LX-2 has been described as tool to study mechanisms of hepatic fibrogenesis and the testing of antifibrotic compounds. It was originally generated by immortalisation with the Simian Vacuolating Virus 40 (SV40) transforming
Externí odkaz:
https://doaj.org/article/13fb714e156d4946b886667d8d892c0f
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