Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lieliang Zhang"'
Autor:
Wei Deng, Yixuan Chen, Jing Zhang, Jitao Ling, Zhou Xu, Zicheng Zhu, Xiaoyi Tang, Xiao Liu, Deju Zhang, Hong Zhu, Haili Lang, Lieliang Zhang, Fuzhou Hua, Shuchun Yu, Kejian Qian, Peng Yu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Objective Mild therapeutic hypothermia (MTH) is an important method for perioperative prevention and treatment of myocardial ischemia–reperfusion injury (MIRI). Modifying mitochondrial proteins after protein translation to regulate mitocho
Externí odkaz:
https://doaj.org/article/785902f219594939978aaccfe0ca3f18
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-22 (2023)
Abstract Background Inflammasomes in astrocytes have been shown to play a crucial role in the pathogenesis of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD). Cannabinoid Receptor 2(CB2R), a G protein-coupled
Externí odkaz:
https://doaj.org/article/15a3f4d08b56415d8ddc12df4f838108
Autor:
Fuzhou Hua, Hong Zhu, Wen Yu, Qingcui Zheng, Lieliang Zhang, Weidong Liang, Yue Lin, Fan Xiao, Pengcheng Yi, Yanhong Xiong, Yao Dong, Hua Li, Lanran Fang, Hailin Liu, Jun Ying, Xifeng Wang
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-25 (2023)
Abstract Postoperative delirium (POD) is a frequent and debilitating complication, especially amongst high risk procedures, such as orthopedic surgery. This kind of neurocognitive disorder negatively affects cognitive domains, such as memory, awarene
Externí odkaz:
https://doaj.org/article/eb9b1189f7124789842a81d09a11e2fa
Association between human blood metabolome and the risk of delirium: a Mendelian Randomization study
Autor:
Chubing Long, Dong Lin, Lieliang Zhang, Yue Lin, Qing Yao, Guangyong Zhang, Longshan Li, Hailin Liu, Jun Ying, Xifeng Wang, Fuzhou Hua
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
BackgroundDelirium significantly contributes to both mortality and morbidity among hospitalized older adults. Furthermore, delirium leads to escalated healthcare expenditures, extended hospital stays, and enduring cognitive deterioration, all of whic
Externí odkaz:
https://doaj.org/article/c86655e002bf41978445bfbec34ab208
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract MOTS-c is a peptide encoded by the short open reading frame of the mitochondrial 12S rRNA gene. It is significantly expressed in response to stress or exercise and translocated to the nucleus, where it regulates the expression of stress adap
Externí odkaz:
https://doaj.org/article/12f764df58ca4717ad15840d2cd91e96
Autor:
Xing Liu, Fuzhou Hua, Danying Yang, Yue Lin, Lieliang Zhang, Jun Ying, Hongguang Sheng, Xifeng Wang
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Neuroligins are postsynaptic cell adhesion molecules that are relevant to many neurodevelopmental disorders. They are differentially enriched at the postsynapse and interact with their presynaptic ligands, neurexins, whose differential bindi
Externí odkaz:
https://doaj.org/article/3bc30383c1f94703b713b3560c83baf2
Dual roles of interleukin-33 in cognitive function by regulating central nervous system inflammation
Autor:
Xiuqin Rao, Fuzhou Hua, Lieliang Zhang, Yue Lin, Pu Fang, Shoulin Chen, Jun Ying, Xifeng Wang
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract With the advent of an aging society, the incidence of dementia is increasing, resulting in a vast burden on society. It is increasingly acknowledged that neuroinflammation is implicated in various neurological diseases with cognitive dysfunc
Externí odkaz:
https://doaj.org/article/d7c08b66504849c2a94095b188130f13
Publikováno v:
Journal of International Medical Research, Vol 51 (2023)
Objective Increasing evidence from randomized controlled trials shows the anti-inflammatory and haemodynamic effects of levosimendan in advanced heart failure (AdHF), however, conflicting results have been reported in some studies. The aim of this st
Externí odkaz:
https://doaj.org/article/38ef37e288714848be65abb6d4892c80
Autor:
Danying Yang, Xifeng Wang, Lieliang Zhang, Yang Fang, Qingcui Zheng, Xing Liu, Wen Yu, Shoulin Chen, Jun Ying, Fuzhou Hua
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The importance of neuroglia in maintaining normal brain function under physiological and pathological conditions has been supported by growing evidence in recent years. The most important issues regarding glial metabolism and function includ
Externí odkaz:
https://doaj.org/article/8ac840051b7444aebf521c1397dbf937
Autor:
Hao Xiong, Fuzhou Hua, Yao Dong, Yue Lin, Jun Ying, Jie Liu, Xifeng Wang, Lieliang Zhang, Jing Zhang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Aging is the continuous degradation of biological function and structure with time, and cellular senescence lies at its core. DNA damage response (DDR) can activate Ataxia telangiectasia-mutated serine/threonine kinase (ATM) and Rad3-related serine/t
Externí odkaz:
https://doaj.org/article/73853d4c337c453c8bdfff43c8ef6359