Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lieke Jäkel"'
Autor:
Emma van denBerg, Rian Roelofs, Lieke Jäkel, Steven M. Greenberg, Andreas Charidimou, Ellis S. vanEtten, Delphine Boche, Catharina J. M. Klijn, Floris H. B. M. Schreuder, H. Bea Kuiperij, Marcel M. Verbeek
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 10, Pp 2563-2571 (2024)
Abstract Objective Elevated levels of anti‐amyloid‐β (anti‐Aβ) autoantibodies in cerebrospinal fluid (CSF) have been proposed as a diagnostic biomarker for cerebral amyloid angiopathy‐related inflammation (CAA‐RI). We aimed to independent
Externí odkaz:
https://doaj.org/article/f04997d5038f46bd999c49f91c98eec6
Autor:
Lieke Jäkel, Anna M. De Kort, Arno Stellingwerf, Carla Hernández Utrilla, Iris Kersten, Marc Vervuurt, Yannick Vermeiren, Benno Küsters, Floris H. B. M. Schreuder, Catharina J. M. Klijn, H. Bea Kuiperij, Marcel M. Verbeek
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Cerebral amyloid angiopathy (CAA) is a highly prevalent and progressive pathology, involving amyloid-β (Aβ) deposition in the cerebral blood vessel walls. CAA is associated with an increased risk for intracerebral hemorrhages (ICH). Insigh
Externí odkaz:
https://doaj.org/article/89e88c86a4f344fb895e0337fee2ad6e
Autor:
Anna M. De Kort, Marcel M. Verbeek, Floris H.B.M. Schreuder, Catharina J.M. Klijn, Lieke Jäkel
Publikováno v:
Journal of Stroke, Vol 26, Iss 2, Pp 179-189 (2024)
Background and Purpose Possible differences in the prevalence of cerebral amyloid angiopathy (CAA) in East-Asian compared to Western populations have received little attention, and results so far have been ambiguous. Our aim is to compare the prevale
Externí odkaz:
https://doaj.org/article/d7a1a659aa644681956f9ecad5e598dd
Autor:
Anna M. De Kort, Kanishk Kaushik, H. Bea Kuiperij, Lieke Jäkel, Hao Li, Anil M. Tuladhar, Gisela M. Terwindt, Marieke J. H. Wermer, Jurgen A. H. R. Claassen, Catharina J. M. Klijn, Marcel M. Verbeek, Roy P. C. Kessels, Floris H. B. M. Schreuder
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Patients with sporadic cerebral amyloid angiopathy (sCAA) frequently report cognitive or neuropsychiatric symptoms. The aim of this study is to investigate whether in patients with sCAA, cognitive impairment and neuropsychiatric s
Externí odkaz:
https://doaj.org/article/03dc076b60694297b5a5dbf562df35bd
Autor:
Anna M. de Kort, H. Bea Kuiperij, Lieke Jäkel, Iris Kersten, Ingeborg Rasing, Ellis S. van Etten, Sanneke van Rooden, Matthias J. P. van Osch, Marieke J. H. Wermer, Gisela M. Terwindt, Floris H. B. M. Schreuder, Catharina J. M. Klijn, Marcel M. Verbeek
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The diagnosis of probable cerebral amyloid angiopathy (CAA) is currently mostly based on characteristics of brain MRI. Blood biomarkers would be a cost-effective, easily accessible diagnostic method that may complement diagnosis b
Externí odkaz:
https://doaj.org/article/06e73ac1710342818de74131702d0e52
Autor:
Marc Vervuurt, Anna M. de Kort, Lieke Jäkel, Iris Kersten, Wilson F. Abdo, Floris H. B. M. Schreuder, Ingeborg Rasing, Gisela M. Terwindt, Marieke J. H. Wermer, Steven M. Greenberg, Catharina J. M. Klijn, H. Bea Kuiperij, Marcel M. Verbeek
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background To evaluate the potential of cerebrospinal fluid (CSF) levels of matrix metalloproteinases and tissue-type inhibitors (MMP; TIMP), and ratios of MMPs to TIMPs, to function as biomarkers for sporadic or hereditary cerebral amyloid
Externí odkaz:
https://doaj.org/article/3560505f068d49d390437f47507aa204
Autor:
Lieke Jäkel, H. Bea Kuiperij, Lara P. Gerding, Emma E. M. Custers, Emma van den Berg, Wilmar M. T. Jolink, Floris H. B. M. Schreuder, Benno Küsters, Catharina J. M. Klijn, Marcel M. Verbeek
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Cerebral amyloid angiopathy (CAA) is characterized by the deposition of the amyloid β (Aβ) protein in the cerebral vasculature and poses a major risk factor for the development of intracerebral haemorrhages (ICH). However, only a minority
Externí odkaz:
https://doaj.org/article/92d9b067964140e0ae4c997452090da9
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Neuropathological follow-up of patients with Alzheimer’s disease (AD) who participated in the first clinical trial of Amyloid-β 42 (Aβ42) immunization (AN1792, Elan Pharmaceuticals) has shown that immunization can induce removal of Aβ42
Externí odkaz:
https://doaj.org/article/58204688505d45afb0d758673b0e7465
Autor:
Anna M. De Kort, H. Bea Kuiperij, Tainá M. Marques, Lieke Jäkel, Emma van den Berg, Iris Kersten, Hugo E. P. van Berckel‐Smit, Marco Duering, Erik Stoops, Wilson F. Abdo, Ingeborg Rasing, Sabine Voigt, Emma A. Koemans, Kanishk Kaushik, Andrew Davock Warren, Steven M. Greenberg, Gunnar Brinkmalm, Gisela M. Terwindt, Marieke J. H. Wermer, Floris H. B. M. Schreuder, Catharina J. M. Klijn, Marcel M. Verbeek
Publikováno v:
Annals of Neurology, 93, 6, pp. 1173-1186
Annals of Neurology, 93, 1173-1186
Annals of Neurology, 93, 1173-1186
Contains fulltext : 293220.pdf (Publisher’s version ) (Open Access) OBJECTIVE: Vascular amyloid β (Aβ) accumulation is the hallmark of cerebral amyloid angiopathy (CAA). The composition of cerebrospinal fluid (CSF) of CAA patients may serve as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815dec2efc47b8bc1bd1a71609844a15
Autor:
Emma van den Berg, Johanna Nilsson, Iris Kersten, Gunnar Brinkmalm, Anna M. de Kort, Catharina J.M. Klijn, Floris H.B.M. Schreuder, Lieke Jäkel, Johan Gobom, Erik Portelius, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow, H. Bea Kuiperij, Marcel M. Verbeek
Publikováno v:
Journal of Alzheimer's Disease, 92, 2, pp. 467-475
Journal of Alzheimer's Disease, 92, 467-475
Journal of Alzheimer's Disease, 92, 467-475
Contains fulltext : 291531.pdf (Publisher’s version ) (Open Access) BACKGROUND: Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA) share pathogenic pathways related to amyloid-β deposition. Whereas AD is known to affect synaptic functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0816f2bc81cc8e38d8e65824799abd
https://doi.org/10.3233/JAD-220977
https://doi.org/10.3233/JAD-220977