Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Liefeng, Wang"'
Autor:
Hongfu Liu, Dongdong Zhou, Dongqin Liu, Xi Xu, Kai Zhang, Ruxia Hu, Peng Xiong, Changxin Wang, Xiangfu Zeng, Liefeng Wang, Shuyong Zhang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-13 (2024)
Abstract Colorectal cancer (CRC) is the third most common cancer associated with a poor prognosis. Effective targeted therapy alone or in combination for treating advanced CRC remains to be a major clinical challenge. Here, we propose the therapeutic
Externí odkaz:
https://doaj.org/article/3198a1e7a948466c9bb43980cd43ecf9
Autor:
Weisong Li, Kai Zhang, Wenjun Wang, Yuanyuan Liu, Jianming Huang, Meihong Zheng, Ling Li, Xinyu Zhang, Minjuan Xu, Guofang Chen, Liefeng Wang, Shuyong Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Ovarian cancer (OC) is a prevalent malignancy in the female reproductive system, and developing effective targeted therapies for this disease remains challenging. The aim of this study was to use clinically-relevant OC models to e
Externí odkaz:
https://doaj.org/article/992c4d49a7ce46ddbcfa4f345b40b71f
Autor:
Chao Zheng, Dongdong Zhou, Weisong Li, Yanhui Duan, Minwen Xu, Jie Liu, Jingpei Cheng, Youban Xiao, Han Xiao, Tao Gan, Jianmin Liang, Dexian Zheng, Liefeng Wang, Shuyong Zhang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-12 (2023)
Abstract Pancreatic cancer (PC) is among the most aggressive malignancies associated with a 5-year survival rate of
Externí odkaz:
https://doaj.org/article/afcde2bb5b1046d696f276725bcef2ab
Autor:
Zilin Zhong, Feng Rong, Yinghui Dai, Alakezi Yibulayin, Lin Zeng, Jian Liao, Liefeng Wang, Zhihua Huang, Zhenping Zhou, Jianjun Chen
Publikováno v:
Molecular Vision, Vol 25, Iss 1, Pp 204-214 (2019)
Purpose: To screen RPE65 in 187 families with Leber congenital amaurosis (LCA). Methods: Sanger sequencing and/or targeted exome sequencing was employed to identify mutations in the RPE65 gene, and intrafamilial cosegregation analysis if DNA was a
Externí odkaz:
https://doaj.org/article/e37f2098e17d4191900e4c42a454a414
Autor:
Choufei Wu, Weijing Yao, Wenwen Kai, Weikang Liu, Wenlve Wang, Shuzhen Li, Yingcong Chen, Xiaoyong Wu, Liefeng Wang, Ying Li, Jingjing Tong, Jing Qian, Liqin Zhang, Zhi Hong, Cong Yi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mitochondria are highly dynamic organelles, which can form a network in cells through fusion, fission, and tubulation. Its morphology is closely related to the function of mitochondria. The damaged mitochondria can be removed by mitophagy. However, t
Externí odkaz:
https://doaj.org/article/048c0b7297f54e979f5b45cc24edfc1a
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
During the entire processes of thymus organogenesis, maturation, and involution, gene regulation occurs post-transcriptionally via recently discovered microRNA (miRNA) transcripts. Numerous reports indicate that miRNAs may be involved in the construc
Externí odkaz:
https://doaj.org/article/809536e330ff4a9b9019b7cb91cf4d99
Publikováno v:
Science of Advanced Materials. 13:1506-1511
Cervical cancer is often treated with surgery, radiotherapy and chemotherapy, but it does not have the advantages of precise treatment and prognosis is not ideal. Molecular targeted therapy can make up for the above shortcomings. This study mainly an
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Age-related thymic involution is primarily induced by defects in nonhematopoietic thymic epithelial cells (TECs). It is characterized by dysfunction of multiple transcription factors (TFs), such as p63 and FoxN1, and also involves other TEC-associate
Externí odkaz:
https://doaj.org/article/2860b39788bf4ba3b73ce61054e5acbb
Autor:
Yanlan Zhu, Choufei Wu, Cong Yi, Yixing Li, Yu Xie, Shu Zhong, Liqin Zhang, Suping Fu, Yuting Chen, Jingjing Tong, Yuyao Feng, Weijing Yao, Liefeng Wang, Yingcong Chen
Publikováno v:
Journal of Genetics and Genomics. 48:512-515
Publikováno v:
Nutrition Research Reviews. 35:28-38
The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) poses a growing challenge in terms of its prevention and treatment. The ‘multiple hits’ hypothesis of multiple insults, such as dietary fat intake, de novo lipogenesis, insuli