Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Lief E. Fenno"'
Autor:
Alexandra Clemente-Perez, Stefanie Ritter Makinson, Bryan Higashikubo, Scott Brovarney, Frances S. Cho, Alexander Urry, Stephanie S. Holden, Matthew Wimer, Csaba Dávid, Lief E. Fenno, László Acsády, Karl Deisseroth, Jeanne T. Paz
Publikováno v:
Cell Reports, Vol 19, Iss 10, Pp 2130-2142 (2017)
Integrative brain functions depend on widely distributed, rhythmically coordinated computations. Through its long-ranging connections with cortex and most senses, the thalamus orchestrates the flow of cognitive and sensory information. Essential in t
Externí odkaz:
https://doaj.org/article/120057556036411083befe76d602d2c5
Autor:
Georg Hafner, Mirko Witte, Julien Guy, Nidhi Subhashini, Lief E. Fenno, Charu Ramakrishnan, Yoon Seok Kim, Karl Deisseroth, Edward M. Callaway, Martina Oberhuber, Karl-Klaus Conzelmann, Jochen F. Staiger
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3450-3461.e8 (2019)
Summary: Parvalbumin (PV)-expressing GABAergic neurons are the largest class of inhibitory neocortical cells. We visualize brain-wide, monosynaptic inputs to PV neurons in mouse barrel cortex. We develop intersectional rabies virus tracing to specifi
Externí odkaz:
https://doaj.org/article/3b0a94c3a99a4d92b25a7502e48bf2a9
Autor:
Kaoru Yamamoto, Zen-ichi Tanei, Tadafumi Hashimoto, Tomoko Wakabayashi, Hiroyuki Okuno, Yasushi Naka, Ofer Yizhar, Lief E. Fenno, Masashi Fukayama, Haruhiko Bito, John R. Cirrito, David M. Holtzman, Karl Deisseroth, Takeshi Iwatsubo
Publikováno v:
Cell Reports, Vol 11, Iss 6, Pp 859-865 (2015)
In vivo experimental evidence indicates that acute neuronal activation increases Aβ release from presynaptic terminals, whereas long-term effects of chronic synaptic activation on Aβ pathology remain unclear. To address this issue, we adopted optog
Externí odkaz:
https://doaj.org/article/735a025e6b604e8cb7fe218382bd6e3a
Autor:
Emily D. Prévost, Alysabeth Phillips, Kristoffer Lauridsen, Gunnar Enserro, Bodhi Rubinstein, Daniel Alas, Dillon J. McGovern, Annie Ly, Makaila Banks, Connor McNulty, Yoon Seok Kim, Lief E. Fenno, Charu Ramakrishnan, Karl Deisseroth, David H. Root
A unique population of ventral tegmental area (VTA) neurons co-transmits glutamate and GABA as well as functionally signals rewarding and aversive outcomes. However, the circuit inputs to VTA VGluT2+VGaT+ neurons are unknown, limiting our understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb794d20eeed59b8fca71e7e271e49d
https://doi.org/10.1101/2023.04.06.535959
https://doi.org/10.1101/2023.04.06.535959
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2501
There is no question that genetically encoded tools have revolutionized neuroscience. These include optically modulated tools for writing-in (optogenetics) and reading-out (calcium, voltage, and neurotransmitter indicators) neural activity as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c1fb149510ea6bf4688855adbeea5d4
https://pubmed.ncbi.nlm.nih.gov/35857234
https://pubmed.ncbi.nlm.nih.gov/35857234
Publikováno v:
Journal of addictive diseases.
The COVID-19 pandemic compelled fast adaptation of telehealth to addiction treatment services. This study aims to examine the feasibility and effectiveness of transitioning an in-person hospital addiction consult service (ACS) to telehealth. The Stan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c758bd14807a16ea4073f51f147abd
https://pubmed.ncbi.nlm.nih.gov/35819268
https://pubmed.ncbi.nlm.nih.gov/35819268
Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals
Autor:
Charu Ramakrishnan, Yoon Seok Kim, Lydia-Marie Joubert, Karl Deisseroth, Kang Shen, Ariane Tom, Jeffrey B.-H. Tok, Huiliang Wang, Yuanwen Jiang, Shucheng Chen, Claire E. Richardson, Xiao Wang, Cheng Wang, Sergiu P. Pașca, Toru Katsumata, Jia Liu, Zhenan Bao, Lief E. Fenno, Fikri Birey
Publikováno v:
Science. 367:1372-1376
From genetics to material to behavior Introducing new genes into an organism can endow new biochemical functions or change the patterns of existing functions, but extending these manipulations to structure at the tissue level is challenging. Combinin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f95391b99705c8b268505a483e93ff
https://doi.org/10.1126/science.aay4866
https://doi.org/10.1126/science.aay4866
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623282
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b2341061f7f27534350c750995af77
https://doi.org/10.1007/978-1-0716-2329-9_14
https://doi.org/10.1007/978-1-0716-2329-9_14
Autor:
Junlang Liu, Paul Chong, Kyrstyn S. Ong, Xiang Wu, Lief E. Fenno, Huiliang Wang, Xingjun Zhu, Ali I. Mahdi, Louis N. Andre, Guosong Hong, Kenneth Brinson, Jiachen Li
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Since the invention of optogenetics, using light to control the activity of individual neurons and dissect the complex neural circuits has been a powerful tool for neuroscience owing to the high temporal precision and neuron-type specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b003b69cd97156d6641c8c1138c2d31e
https://doi.org/10.1073/pnas.1914387116
https://doi.org/10.1073/pnas.1914387116
Autor:
Karl Deisseroth, Szabina Furdan, Antoine Roger Adamantidis, Charu Ramakrishnan, Magor L. Lőrincz, Joanna Mattis, Giuseppe Di Giovanni, Mary Gazea, Susan M. Dymecki, Lief E. Fenno, Benedek Molnár, Péter Sere, Lukas T Oesch
Publikováno v:
J Neurosci
The lateral hypothalamus (LH), together with multiple neuromodulatory systems of the brain, such as the dorsal raphe nucleus (DR), is implicated in arousal, yet interactions between these systems are just beginning to be explored. Using a combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9205e5ad675afabe9854cf3800199359
https://orca.cardiff.ac.uk/id/eprint/146754/1/reciprocal_4840.full.pdf
https://orca.cardiff.ac.uk/id/eprint/146754/1/reciprocal_4840.full.pdf