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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Takahashi RH; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Malhi V; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California malhi.vikram@gene.com., Liederer BM; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Cho S; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Deng Y; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Dean B; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Nugteren J; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Yost E; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Al-Sayah MA; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Sane R; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Kshirsagar S; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Ma S; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California., Musib L; Drug Metabolism and Pharmacokinetics (R.H.T., B.M.L., S.C., Y.D., B.D., S.M.), Clinical Pharmacology (V.M., R.S., S.K., L.M.), BioAnalytical Sciences (J.N.), Small Molecule Pharmaceutics (E.Y.), and Small Molecule Analytical Chemistry (M.A.A.-S.), Genentech Inc., South San Francisco, California.
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2023 Oct; Vol. 51 (10), pp. 1332-1341. Date of Electronic Publication: 2023 Jul 31.
Autor:
Chan P; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Ding HT; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Liederer BM; Department of Drug Metabolism & Pharmacokinetics, Genentech, Inc, South San Francisco, California, USA., Mao J; Department of Drug Metabolism & Pharmacokinetics, Genentech, Inc, South San Francisco, California, USA., Belloni P; Department of Clinical Sciences, Early Clinical Development, Genentech, Inc, South San Francisco, California, USA., Chen L; Department of Drug Metabolism & Pharmacokinetics, Genentech, Inc, South San Francisco, California, USA., Gao SS; Department of Clinical Imaging, Genentech, Inc, South San Francisco, California, USA., Joseph V; Department of Biomedical Imaging, Genentech, Inc, South San Francisco, California, USA., Yang X; Department of Biostatistics, Early Clinical Development, Genentech, Inc, South San Francisco, California, USA., Lin JS; Department of Clinical Sciences, Early Clinical Development, Genentech, Inc, South San Francisco, California, USA., Mitra MS; Department of Toxicology, Genentech, Inc, South San Francisco, California, USA., Putnam WS; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Quartino A; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA., Bauer RN; Department of Biomarker Development, Early Clinical Development, Genentech, Inc, South San Francisco, California, USA., Pan L; Department of Clinical Pharmacology, Genentech, Inc, South San Francisco, California, USA.
Publikováno v:
Clinical and translational science [Clin Transl Sci] 2021 Sep; Vol. 14 (5), pp. 1945-1954. Date of Electronic Publication: 2021 May 31.
Autor:
Sane RS; Genentech, South San Francisco, California saner@gene.com., Cheung KWK; Genentech, South San Francisco, California., Cho E; Genentech, South San Francisco, California., Liederer BM; Genentech, South San Francisco, California., Hanover J; Genentech, South San Francisco, California., Malhi V; Genentech, South San Francisco, California., Plise E; Genentech, South San Francisco, California., Wong S; Genentech, South San Francisco, California., Musib L; Genentech, South San Francisco, California.
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2021 Aug; Vol. 378 (2), pp. 87-95. Date of Electronic Publication: 2021 May 28.
Autor:
Balestrini A; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Joseph V; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Dourado M; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Reese RM; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Shields SD; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Rougé L; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Bravo DD; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Chernov-Rogan T; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Austin CD; Department of Pathology, Genentech, Inc., South San Francisco, CA., Chen H; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Wang L; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Villemure E; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Shore DGM; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Verma VA; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Hu B; Pharmaron-Beijing Co. Ltd., BDA, Beijing, People's Republic of China., Chen Y; Pharmaron-Beijing Co. Ltd., BDA, Beijing, People's Republic of China., Leong L; Department of Pathology, Genentech, Inc., South San Francisco, CA., Bjornson C; Department of Pathology, Genentech, Inc., South San Francisco, CA., Hötzel K; Department of Pathology, Genentech, Inc., South San Francisco, CA., Gogineni A; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Lee WP; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Suto E; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Wu X; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Liu J; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Zhang J; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Gandham V; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Wang J; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Payandeh J; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Ciferri C; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Estevez A; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Arthur CP; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Kortmann J; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Wong RL; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Heredia JE; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Doerr J; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA., Jung M; Department of OMNI Bioinformatics, Genentech, Inc., South San Francisco, CA., Vander Heiden JA; Department of OMNI Bioinformatics, Genentech, Inc., South San Francisco, CA., Roose-Girma M; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA., Tam L; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA., Barck KH; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Carano RAD; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Ding HT; Department of Clinical Pharmacology, Genentech, Inc., South San Francisco, CA., Brillantes B; Department of Biomolecular Resources, Genentech, Inc., South San Francisco, CA., Tam C; Department of Biomolecular Resources, Genentech, Inc., South San Francisco, CA., Yang X; Department of Product Development Biometric Biostatistics, Genentech, Inc., South San Francisco, CA., Gao SS; Department of Clinical Imaging, Genentech, Inc., South San Francisco, CA., Ly JQ; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Liu L; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Chen L; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Liederer BM; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Lin JH; Department of Early Clinical Development, Genentech, Inc., South San Francisco, CA., Magnuson S; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Chen J; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Hackos DH; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Elstrott J; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Rohou A; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Safina BS; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Volgraf M; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Bauer RN; Department of OMNI-Biomarker Development, Genentech, Inc., South San Francisco, CA., Riol-Blanco L; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA.
Publikováno v:
The Journal of experimental medicine [J Exp Med] 2021 Apr 05; Vol. 218 (4).