Výsledky vyhledávání - "Liechtenstein, T."

Dissertation/ Thesis

Lentivector-based cancer immunotherapy silencing PD-L1 and modulating cytokine priming : development of ex vivo myeloid-derived suppressor cells to assess therapeutic efficacy

Autor: Liechtenstein, T. M.

Cancer immunotherapy strategies based on lentiviral vector (lentivector) transduction have recently been shown to be safe and effective in the clinic. The objective of cancer immunotherapy is to induce anti-cancer immune responses. Cytotoxic T cell (

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.668501

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Inmunoterapia genética con células dendríticas para el tratamiento del cáncer

Autor: Gato, M., Liechtenstein, T., Blanco-Luquín, I., Zudaire, M.I., Kochan, G., Escors, D.

Publikováno v: Anales del Sistema Sanitario de Navarra, Volume: 38, Issue: 2, Pages: 279-287, Published: AUG 2015

Desde comienzos del siglo XX, los científicos han intentado aprovechar las actividades naturales del sistema inmunológico para curar el cáncer. Sin embargo, las inmunoterapias no han dado el resultado clínico que podría haberse esperado. De hech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______624::901485d4eb73bbdae936268108abf5e4
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1137-66272015000200012&lng=en&tlng=en

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Interference with PD-L1/PD-1 co-stimulation results in effective anti-tumour immunity by preventing ligand-induced T cell receptor

Autor: Escors, D., Liechtenstein, T., Perez-Janices, N., Lanna, A., Bricogne, C., Karwaca, K., Guerrero-Setas, D., Breckpot, Karine

T cell receptor (TCR) down-modulation after antigen presentation is a fundamental process that regulates TCR signal transduction. Current understanding of this process is that intrinsic TCR/CD28 signal transduction leads to TCR down-modulation. We de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3848::9c35726818edbbcf5732e9515843788e
https://biblio.vub.ac.be/vubir/interference-with-pdl1pd1-costimulation-results-in-effective-antitumour-immunity-by-preventing-ligandinduced-t-cell-receptor(0ce03005-ef14-4b77-9e63-84c278dc07a8).html

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Modulating co-stimulation during antigen presentation to enhance cancer immunotherapy

Autor: Liechtenstein, T., Perez-Janices, N., Karine Breckpot, Escors, D.

Publikováno v: ResearcherID

Dendritic cells (DCs) are the most potent professional antigen presenting cells (APCs) of the immune system. DCs provide three different signals to activate effector T cells during antigen presentation. Signal 1 is delivered by the binding of the T c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7ac1e2c880564ace45604cbfd2914844
https://biblio.vub.ac.be/vubir/modulating-costimulation-during-antigen-presentation-to-enhance-cancer-immunotherapy(a9e97b27-4c9c-44dd-ae3d-c41fa5f5190f).html

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PD-L1/PD-1 Co-Stimulation, a Brake for T cell Activation and a T cell Differentiation Signal

Autor: Liechtenstein, T., Inès Dufait, Bricogne, C., Lanna, A., Joeri Pen, Karine Breckpot, Escors, D.

Publikováno v: Vrije Universiteit Brussel

For T cell activation, three signals have to be provided from the antigen presenting cell; Signal 1 (antigen recognition), signal 2 (co-stimulation) and signal 3 (cytokine priming). Blocking negative co-stimulation during antigen presentation to T ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e9659ae731cd05fd53c7fec36fdf9c52
https://europepmc.org/articles/PMC3605779/

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