Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lidza Kalifa"'
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005664 (2015)
Mitochondria contain an independently maintained genome that encodes several proteins required for cellular respiration. Deletions in the mitochondrial genome have been identified that cause several maternally inherited diseases and are associated wi
Externí odkaz:
https://doaj.org/article/69ec371904ce408fb689c4566c19114b
Autor:
Lidza Kalifa, Alexis Stein, Prabha Nagarajan, Rachel Kasimer, Elaine A. Sia, Christopher T Prevost
Publikováno v:
Genetics. 206:843-857
The structure-specific nuclease, Rad27p/FEN1, plays a crucial role in DNA repair and replication mechanisms in the nucleus. Genetic assays using the rad27-∆ mutant have shown altered rates of DNA recombination, microsatellite instability, and point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a0fb84aa3e11a21cae71e65405c5395
https://doi.org/10.1534/genetics.116.195149
https://doi.org/10.1534/genetics.116.195149
Roles for the Rad27 Flap Endonuclease in Mitochondrial Mutagenesis and Double-Strand Break Repair in
Autor:
Prabha, Nagarajan, Christopher T, Prevost, Alexis, Stein, Rachel, Kasimer, Lidza, Kalifa, Elaine A, Sia
Publikováno v:
Genetics. 206(2)
The structure-specific nuclease, Rad27p/FEN1, plays a crucial role in DNA repair and replication mechanisms in the nucleus. Genetic assays using the rad27-∆ mutant have shown altered rates of DNA recombination, microsatellite instability, and point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64903a96b830e1573fc7d494daa3010e
https://pubmed.ncbi.nlm.nih.gov/28450457
https://pubmed.ncbi.nlm.nih.gov/28450457
Autor:
Daniel F Quintana, Lidza Kalifa, Garry L Coles, Laura K Schiraldi, Rey A. L. Sia, Naina Phadnis, Elaine A. Sia
Publikováno v:
Genetics. 190:951-964
Mitochondrial DNA (mtDNA) deletions are associated with sporadic and inherited diseases and age-associated neurodegenerative disorders. Approximately 85% of mtDNA deletions identified in humans are flanked by short directly repeated sequences; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d97cfe295486fc4d126ed92c272534
https://doi.org/10.1534/genetics.111.138214
https://doi.org/10.1534/genetics.111.138214
Publikováno v:
DNA Repair. 8:1242-1249
Although the nuclear processes responsible for genomic DNA replication and repair are well characterized, the pathways involved in mitochondrial DNA (mtDNA) replication and repair remain unclear. DNA repair has been identified as being particularly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b72613644d2e86416b5224f89c377de
https://doi.org/10.1016/j.dnarep.2009.07.008
https://doi.org/10.1016/j.dnarep.2009.07.008
Autor:
Elaine A. Sia, Lidza Kalifa
Publikováno v:
DNA Repair. 6:1732-1739
Ultraviolet light is a potent DNA damaging agent that induces bulky lesions in DNA which block the replicative polymerases. In order to ensure continued DNA replication and cell viability, specialized translesion polymerases bypass these lesions at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d714510e5f6c9a8931e470a7b9709d3a
https://doi.org/10.1016/j.dnarep.2007.06.005
https://doi.org/10.1016/j.dnarep.2007.06.005
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005664 (2015)
PLoS Genetics
PLoS Genetics
Mitochondria contain an independently maintained genome that encodes several proteins required for cellular respiration. Deletions in the mitochondrial genome have been identified that cause several maternally inherited diseases and are associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f428d3449a77dbbd0b0920914a70f4ff
http://europepmc.org/articles/PMC4634946?pdf=render
http://europepmc.org/articles/PMC4634946?pdf=render
Autor:
Michael A. O'Reilly, Paul S. Brookes, Rhonda J. Staversky, Elaine A. Sia, Jennifer S. Gewandter, Lidza Kalifa
Publikováno v:
Free radical biologymedicine. 75
Excessive nuclear or mitochondrial DNA damage can lead to mitochondrial dysfunction, decreased energy production, and increased generation of reactive oxygen species (ROS). Although numerous cell signaling pathways are activated when cells are injure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbefc622f57f6e881f8490312532ffc3
https://pubmed.ncbi.nlm.nih.gov/25048973
https://pubmed.ncbi.nlm.nih.gov/25048973
Autor:
Lidza Kalifa, Michael A. O'Reilly
Publikováno v:
Mitochondrial Function in Lung Health and Disease ISBN: 9781493908288
The primary function of the lung is to facilitate the exchange of oxygen and carbon dioxide between air and blood and to exclude or defend against infectious agents and other airborne pollutants. As such, the respiratory epithelium is under constant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a78c1017ee4c5a349a0291a858e096c
https://doi.org/10.1007/978-1-4939-0829-5_7
https://doi.org/10.1007/978-1-4939-0829-5_7
