Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.

Autor: Engeholm M; Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany. Electronic address: maik.engeholm@mpinat.mpg.de., Roske JJ; Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Oberbeckmann E; Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany., Dienemann C; Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany., Lidschreiber M; Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany., Cramer P; Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany. Electronic address: patrick.cramer@mpinat.mpg.de., Farnung L; Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, Göttingen 37077, Germany; Harvard Medical School, Blavatnik Institute, Department of Cell Biology, 240 Longwood Avenue, Boston, MA 02115, USA. Electronic address: lucas_farnung@hms.harvard.edu.

Publikováno v: Molecular cell [Mol Cell] 2024 Sep 19; Vol. 84 (18), pp. 3423-3437.e8. Date of Electronic Publication: 2024 Sep 12.

Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells.

Autor: Palau A; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Segerberg F; Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden., Lidschreiber M; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; Department of Molecular Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Lidschreiber K; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Naughton AJ; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Needhamsen M; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Solna, Sweden., Jung LA; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Jagodic M; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Solna, Sweden., Cramer P; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; Department of Molecular Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Lehmann S; Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden. soren.lehmann@ki.se.; Hematology Centre, Karolinska University Hospital, Stockholm, Sweden. soren.lehmann@ki.se.; Hematology Unit, Department of Medical Sciences, Uppsala University, Uppsala, Sweden. soren.lehmann@ki.se., Carlsten M; Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden. mattias.carlsten@ki.se.; Center for Cell Therapy and Allogeneic Stem Cell Transplantation, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, Stockholm, Sweden. mattias.carlsten@ki.se., Lennartsson A; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden. andreas.lennartsson@ki.se.

Publikováno v: Leukemia [Leukemia] 2023 Sep; Vol. 37 (9), pp. 1830-1841. Date of Electronic Publication: 2023 Jul 26.

Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.

Autor: Abril-Garrido J; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany., Dienemann C; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany., Grabbe F; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany., Velychko T; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany., Lidschreiber M; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany., Wang H; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: haibo.wang@zju.edu.cn., Cramer P; Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: pcramer@mpinat.mpg.de.

Publikováno v: Molecular cell [Mol Cell] 2023 Jun 01; Vol. 83 (11), pp. 1798-1809.e7. Date of Electronic Publication: 2023 May 05.

Sequence determinants of human gene regulatory elements.

Autor: Sahu B; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Medicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Hartonen T; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Pihlajamaa P; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Wei B; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Dave K; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Zhu F; Department of Biochemistry, University of Cambridge, Cambridge, UK., Kaasinen E; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Lidschreiber K; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Lidschreiber M; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Daub CO; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden., Cramer P; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden., Kivioja T; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Taipale J; Applied Tumor Genomics Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland. ajt208@cam.ac.uk.; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. ajt208@cam.ac.uk.; Department of Biochemistry, University of Cambridge, Cambridge, UK. ajt208@cam.ac.uk.

Publikováno v: Nature genetics [Nat Genet] 2022 Mar; Vol. 54 (3), pp. 283-294. Date of Electronic Publication: 2022 Feb 21.

Efficient RNA polymerase II pause release requires U2 snRNP function.

Autor: Caizzi L; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Monteiro-Martins S; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Schwalb B; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Lysakovskaia K; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Schmitzova J; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Sawicka A; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Chen Y; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Lidschreiber M; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany., Cramer P; Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: patrick.cramer@mpibpc.mpg.de.

Publikováno v: Molecular cell [Mol Cell] 2021 May 06; Vol. 81 (9), pp. 1920-1934.e9. Date of Electronic Publication: 2021 Mar 08.