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Akademický článek

Statistical and network analyses reveal mechanisms for the enhancement of macrophage immunity by manganese in Mycobacterium tuberculosis infection

Autor: Lidong Shan, Zihai Wang, Lingshan Wu, Kaiqiang Qian, Guisen Peng, MeiLi Wei, Bikui Tang, Xi Jun

Publikováno v: Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101602- (2024)

Tuberculosis is a significant infectious disease that poses a serious risk to human health. Our previous research has indicated that manganese ions reduce the bacterial load of Mycobacterium tuberculosis in macrophages, but the exact immune defense m

Externí odkaz: https://doaj.org/article/8ec3c0f07cda4211a20a90fe6a026b4f

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Akademický článek

Electrical stimulation of the superior sagittal sinus suppresses A-type K+ currents and increases P/Q- and T-type Ca2+ currents in rat trigeminal ganglion neurons

Autor: Junping Cao, Yuan Zhang, Lei Wu, Lidong Shan, Yufang Sun, Xinghong Jiang, Jin Tao

Publikováno v: The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-12 (2019)

Abstract Background Migraine is a debilitating neurological disorder involving abnormal trigeminovascular activation and sensitization. However, the underlying cellular and molecular mechanisms remain unclear. Methods A rat model of conscious migrain

Externí odkaz: https://doaj.org/article/9dd186a534df4d04be4bba485a77e3f9

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An Organic Molecular Probe for the Fluorescence Detection of Fe3+ and Photocurrent Response

Autor: Lidong Shan, Baozhen Li, Wei Fu

Publikováno v: Journal of Analytical Chemistry. 78:185-193

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c70874eae2c98727acda99c4941842f
https://doi.org/10.1134/s1061934823020119

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Tandem Synthesis of 2-Azaspiro[4.5]deca-1,6,9-trien-8-ones Based on Tf2O-Promoted Activation of N-(2-Propyn-1-yl) Amides

Autor: Lidong Shan, Hongchen Li, Weiping Zheng, Xingyong Wang, Xinyan Wang, Yuefei Hu

Publikováno v: The Journal of Organic Chemistry. 88:525-533

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebf3ea55319481d4a1cd18ebd990666b
https://doi.org/10.1021/acs.joc.2c02504

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Mechanistic Insights into Tf2O-Promoted Electrophilic Activation of 2-Propynamides and a New Synthesis of 2,4-Disubstituted Quinolines

Autor: Lidong Shan, Hongchen Li, Weiping Zheng, Xingyong Wang, Xinyan Wang, Yuefei Hu

Publikováno v: Organic Letters. 24:8806-8811

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85f56b06d17a05f4587113f89cb48c9c
https://doi.org/10.1021/acs.orglett.2c03565

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Identification and validation of a novel redox- related differentially expressed lncRNA prognostic signature for predicting clinical immunotherapy response in gastric cancer

Autor: Guisen Peng, Di Wu, Lidong Shan, Weicheng Lu, Mingjie Hu, Mulin Liu, Huazhang Wu

Redox responses modulated by intracellular long noncoding RNA (lncRNA) can be involved in tumorigenesis and progression. However, the role of redox-related lncRNAs (RRlncRNAs) in gastric cancer (GC) development remains mostly unknown. Our research ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca0dfcbe85e54a727c40d270600f87bf
https://doi.org/10.21203/rs.3.rs-2843204/v1

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Bischler–Napieralski Synthesis of Polycyclic N-Heteroaromatics Based on Tf2O-Promoted Electrophilic Activation of N-Aryl-2-Propynamides

Autor: Lidong Shan, Yunxiang Weng, Hongchen Li, Lin Min, Xinyan Wang, Yuefei Hu

Publikováno v: The Journal of Organic Chemistry. 87:4124-4133

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4e10b404913ab507cb03d40dae314ee
https://doi.org/10.1021/acs.joc.1c02918

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Bischler–Napieralski Synthesis of 6-Alkynyl Phenanthridines Based on Tf2O-Promoted Electrophilic Activation of N-Aryl-2-propynamides

Autor: Yunxiang Weng, Hongchen Li, Yuefei Hu, Lin Min, Lidong Shan, Xinyan Wang

Publikováno v: The Journal of Organic Chemistry. 86:15726-15732

An efficient method for the synthesis of 6-alkynyl phenanthridines was developed. The method offered the first example to use 2-propynamides as substrates in the Bischler-Napieralski reaction and to create alkynylnitrilium triflates as new active int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bc48f963c0e56fc58c5e14e2618a7f0
https://doi.org/10.1021/acs.joc.1c01543

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The role of neoantigens in tumor immunotherapy

Autor: Shengwen Shang, Yongjie Zhao, Kaiqiang Qian, Yuexuan Qin, Xinyi Zhang, Tianyue Li, Lidong Shan, Meili Wei, Jun Xi, Bikui Tang

Publikováno v: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 151

Tumor neoantigens are aberrant polypeptides produced by tumor cells as a result of genomic mutations. They are also tumor-specific antigens (TSA). Neoantigens are more immunogenic than tumor-related antigens and do not induce autoimmunity. Based on t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8435f1ce0c84d01fed499dfa2fc358
https://pubmed.ncbi.nlm.nih.gov/35623169

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