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Akademický článek

Association between multiple-heavy-metal exposures and systemic immune inflammation in a middle-aged and elderly Chinese general population

Publikováno v: BMC Public Health, Vol 24, Iss 1, Pp 1-14 (2024)

Abstract Background Exposure to heavy metals alone or in combination can promote systemic inflammation. The aim of this study was to investigate potential associations between multiple plasma heavy metals and markers of systemic immune inflammation.

Externí odkaz: https://doaj.org/article/e25e74b605d946418570b3d3aab8b589

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Akademický článek

Correlations between growth differentiation factor 15 (GDF-15) serum levels and gene polymorphism with type 2 diabetes mellitus

Publikováno v: Heliyon, Vol 10, Iss 12, Pp e33044- (2024)

Purpose: To date, the relationship between Growth Differentiation Factor 15 (GDF-15) gene polymorphism and the risk of type 2 diabetes mellitus (T2DM) has not been clarified. Our study aims to explore the association between serum GDF-15 levels and r

Externí odkaz: https://doaj.org/article/1db13833e6b34e3ba57671ba58c5cc3f

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Akademický článek

Low-carbon operation optimization of integrated energy system considering CCS-P2G and multi-market interaction

Autor: Lidong Qin, Hengrui Ma, Cunqiang Huang, Hongxia Li, Shidong Wu, Gangfei Wang

Publikováno v: Frontiers in Energy Research, Vol 11 (2024)

Integrated energy system is crucial in realizing China’s “dual carbon” targets. Considering the carbon capture based electricity to gas and the interaction of multiple markets, this paper proposes a low-carbon operation optimization method of i

Externí odkaz: https://doaj.org/article/3b14ee6273814c75b2fbecb3b5b4777e

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Akademický článek

Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism

Autor: Ruofan Yu, Xiaohua Cao, Luyang Sun, Jun-yi Zhu, Brian M Wasko, Wei Liu, Emeline Crutcher, Haiying Liu, Myeong Chan Jo, Lidong Qin, Matt Kaeberlein, Zhe Han, Weiwei Dang

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Histone acetylations are important epigenetic marks for transcriptional activation and respond to metabolic changes. Here the authors develop a lifespan screen and show that inactivation of the histone deacetylase complex activates longevity and prot

Externí odkaz: https://doaj.org/article/5fc58828c7fb441ca6310e633e6239e1

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Akademický článek

Evaluation of Single-Cell Cytokine Secretion and Cell-Cell Interactions with a Hierarchical Loading Microwell Chip

Autor: Yufu Zhou, Ning Shao, Ricardo Bessa de Castro, Pengchao Zhang, Yuan Ma, Xin Liu, Feizhou Huang, Rong-Fu Wang, Lidong Qin

Publikováno v: Cell Reports, Vol 31, Iss 4, Pp - (2020)

Summary: Comprehensive evaluation of single T cell functions such as cytokine secretion and cytolysis of target cells is greatly needed in adoptive cell therapy (ACT) but has never been fully fulfilled by current approaches. Herein, we develop a hier

Externí odkaz: https://doaj.org/article/5824e0b9412e45449d51dc9529a63e5f

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Akademický článek

Human equilibrative nucleoside transporter-1 knockdown tunes cellular mechanics through epithelial-mesenchymal transition in pancreatic cancer cells.

Autor: Yeonju Lee, Eugene J Koay, Weijia Zhang, Lidong Qin, Dickson K Kirui, Fazle Hussain, Haifa Shen, Mauro Ferrari

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e107973 (2014)

We report cell mechanical changes in response to alteration of expression of the human equilibrative nucleoside transporter-1 (hENT1), a most abundant and widely distributed plasma membrane nucleoside transporter in human cells and/or tissues. Modula

Externí odkaz: https://doaj.org/article/2760aae45e904ecb92472acb9b678990

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