Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lidiya A, Petrushova"'
Autor:
Svitlana V. Shishkina, Lidiya A. Petrushova, Kateryna O. Burian, Andrii I. Fedosov, Igor V. Ukrainets
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 10, Pp 1657-1660 (2020)
The title compound, C10H8ClNO5S, which has potential analgesic activity, crystallizes in space group P21/n. The benzothiazine ring system adopts an intermediate form between sofa and twist-boat conformations. The coplanarity of the ester substituent
Externí odkaz:
https://doaj.org/article/45391d17d89e4e8b901bc9c428dfca7e
Autor:
Igor V. Ukrainets, Lidiya A. Petrushova, Svitlana V. Shishkina, Lina A. Grinevich, Galina Sim
Publikováno v:
Scientia Pharmaceutica, Vol 84, Iss 4, Pp 705-714 (2016)
In order to obtain and then test pharmocologically any possible conformers of the new feasible analgesic N-benzyl-4-hydroxy-1-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide, its 4-O-sodium salt was synthesized using two methods. X-ray diffrac
Externí odkaz:
https://doaj.org/article/897c84164b3a48feb96bef9ab2f43043
Autor:
Igor V. Ukrainets, Lidiya A. Petrushova, Svitlana V. Shishkina, Lyudmila V. Sidorenko, Tatiana V. Alekseeva, Inna I. Torianyk, Alexandra A. Davidenko
Publikováno v:
Scientia Pharmaceutica, Vol 88, Iss 1, p 10 (2020)
In order to identify new regularities of the “structure−analgesic activity” relationship in the series of 2,1-benzothiazine derivatives, the synthesis of methyl 4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate and a group of its analog
Externí odkaz:
https://doaj.org/article/4696a8b945a2491385221d3aa25cabdd
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 7, Pp o786-o787 (2014)
The title solvate, C20H14N4O4S·C3H7NO, comprises a stereogenic centre but the centrosymmetric space group causes the presence of the racemate in the crystal. The spiro-joined fragments are almost orthogonal, with a dihedral angle of 86.8 (2)° betwe
Externí odkaz:
https://doaj.org/article/074623cc1b5045109b3cf41af77fab51
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 11, Pp o1698-o1698 (2013)
There are two independent molecules in the asymmetric unit of the title compound, C13H13NO5S, in both of which the ester substituent is nearly coplanar [C—C—C—O torsion angles = 2.7 (7) and −0.8 (7)°] with the planar fragment of the bicycle
Externí odkaz:
https://doaj.org/article/5781d96bde5b42618204fa76bfc27611
Autor:
Svitlana V, Shishkina, Lidiya A, Petrushova, Kateryna O, Burian, Andrii I, Fedosov, Igor V, Ukrainets
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications
The molecular and crystal structure as well as the Hirshfeld surface were analysed for this benzothiazine derivative with potential analgesic activity.
The title compound, C10H8ClNO5S, which has potential analgesic activity, crystallizes i
The title compound, C10H8ClNO5S, which has potential analgesic activity, crystallizes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55ceb677dff9ce1075006ec28108f70b
https://pubmed.ncbi.nlm.nih.gov/33117584
https://pubmed.ncbi.nlm.nih.gov/33117584
Autor:
Svitlana V, Shishkina, Igor V, Ukrainets, Olga V, Vashchenko, Natali I, Voloshchuk, Pavlo S, Bondarenko, Lidiya A, Petrushova, Galina, Sim
Publikováno v:
Acta crystallographica. Section C, Structural chemistry. 76(Pt 1)
The title benzothiazine-3-carboxamide, C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::649cf2b86652682117263404cb466cca
https://pubmed.ncbi.nlm.nih.gov/31919309
https://pubmed.ncbi.nlm.nih.gov/31919309
Autor:
Igor V, Ukrainets, Lidiya A, Petrushova, Lyudmila V, Sidorenko, Alexandra A, Davidenko, Marina A, Duchenko
Publikováno v:
Scientia Pharmaceutica
In continuing the search for new analgesics among derivatives of 2,1-benzothiazines, a series of corresponding toluidides and xylidides of 4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylic acid has been synthesized by the reaction of ethyl 4-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f13fcb9fa8aeffb880a97d771e6742e
https://pubmed.ncbi.nlm.nih.gov/28117315
https://pubmed.ncbi.nlm.nih.gov/28117315
Publikováno v:
Scientia Pharmaceutica
A new, effective preparative method has been proposed and the synthesis of a series of N-(arylalkyl)-1-R-4-hydroxy-2,2-dioxo-1H-2λ(6),1-benzothiazine-3-car-boxamides has been carried out. It has been shown that amidation of alkyl 1-R-4-hydroxy-2,2-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f28713d2e8a1a211fb2346c997c477c
https://pubmed.ncbi.nlm.nih.gov/26839838
https://pubmed.ncbi.nlm.nih.gov/26839838