Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lidija K. Gorsic"'
Autor:
M. Eileen Dolan, Yusuke Nakamura, Wei Zhang, Deanna L. Kroetz, Michiaki Kubo, Atsushi Takahashi, Lidija K. Gorsic, Shannon M. Delaney, Claudia Wing, Siew-Kee Low, Suyoun Chung, Heather E. Wheeler, Masaaki Komatsu
Purpose: Paclitaxel is used worldwide in the treatment of breast, lung, ovarian, and other cancers. Sensory peripheral neuropathy is an associated adverse effect that cannot be predicted, prevented, or mitigated. To better understand the contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fb7388c7dd9fe5696b81b6053c2e86
https://doi.org/10.1158/1078-0432.c.6524187.v1
https://doi.org/10.1158/1078-0432.c.6524187.v1
Autor:
Amy L Stark, Ronald J Hause, Lidija K Gorsic, Nirav N Antao, Shan S Wong, Sophie H Chung, Daniel F Gill, Hae K Im, Jamie L Myers, Kevin P White, Richard Baker Jones, M Eileen Dolan
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004192 (2014)
Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitative trait loci is an expanding and useful approach, but focuses exclusively on mRNA r
Externí odkaz:
https://doaj.org/article/d70e8f5d77ad47efb599e099fdb8de61
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82220 (2013)
Cisplatin, a commonly used chemotherapeutic, is associated with ototoxicity, renal toxicity and neurotoxicity, thus identifying means to increase the therapeutic index of cisplatin may allow for improved outcomes. A SNP (rs4343077) within EPS8, disco
Externí odkaz:
https://doaj.org/article/1f9bbadbb5ef4122a12673d49cc2f486
Autor:
Heather E Wheeler, Lidija K Gorsic, Marleen Welsh, Amy L Stark, Eric R Gamazon, Nancy J Cox, M Eileen Dolan
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21920 (2011)
Chemotherapeutic agents are used in the treatment of many cancers, yet variable resistance and toxicities among individuals limit successful outcomes. Several studies have indicated outcome differences associated with ancestry among patients with var
Externí odkaz:
https://doaj.org/article/ffe6859f30e64a0eb70be25a841a6a2e
Autor:
Alexias Safi, Steven T. Kosak, Jenny L. Kerschner, Gregory E. Crawford, Lidija K. Gorsic, Daniel S. Neems, Rui Yang, Shih Hsing Leir, Nehal Gosalia, Ann Harris
Publikováno v:
Nucleic Acids Research
Higher order chromatin structure establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of individual loci within a topological domain (TAD) are not fully understood. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d28eb45f4c4408fbb19d12f1a0005e4
https://doi.org/10.1093/nar/gkv1358
https://doi.org/10.1093/nar/gkv1358
Autor:
Wei Zhang, Shannon M. Delaney, Yusuke Nakamura, M. Eileen Dolan, Lidija K. Gorsic, Deanna L. Kroetz, Claudia Wing, Atsushi Takahashi, Michiaki Kubo, Suyoun Chung, Siew-Kee Low, Masaaki Komatsu, Heather E. Wheeler
Publikováno v:
Clinical Cancer Research. 21:4337-4346
Purpose: Paclitaxel is used worldwide in the treatment of breast, lung, ovarian, and other cancers. Sensory peripheral neuropathy is an associated adverse effect that cannot be predicted, prevented, or mitigated. To better understand the contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ef68d49cbcc2695eb06821e1f73aa1
https://doi.org/10.1158/1078-0432.ccr-15-0133
https://doi.org/10.1158/1078-0432.ccr-15-0133
Autor:
Ronald J. Hause, Amy L. Stark, Lidija K. Gorsic, Mark F. Ciaccio, Ashraf G. Madian, Vincent C. Chen, Amy L. Gill, Lida Anita To, M. Eileen Dolan, Sawyer W. Williams, Richard B. Jones, Claudia Wing, Kevin P. White, Jamie Myers
Publikováno v:
Journal of proteome research. 16(11)
Determining the effect of chemotherapeutic treatment on changes in protein expression can provide important targets for overcoming resistance. Due to challenges in simultaneously measuring large numbers of proteins, a paucity of data exists on global
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f9342a0cf3aa09b5085c433793faf8
https://pubmed.ncbi.nlm.nih.gov/28902521
https://pubmed.ncbi.nlm.nih.gov/28902521
Autor:
Andrea Dunaif, Ryan Sisk, M. Geoffrey Hayes, Richard S. Legro, Gulum Kosova, Lidija K. Gorsic, José A. Teixeira, Margrit Urbanek, Brian Werstein
Publikováno v:
The Journal of clinical endocrinology and metabolism. 102(8)
Context Polycystic ovary syndrome (PCOS), a common endocrine condition, is the leading cause of anovulatory infertility. Objective Given that common disease-susceptibility variants account for only a small percentage of the estimated PCOS heritabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f63f67f3f7428140e57b7b4574a34be
https://pubmed.ncbi.nlm.nih.gov/28505284
https://pubmed.ncbi.nlm.nih.gov/28505284
Autor:
Nirav N. Antao, Sophie H. Chung, Lidija K. Gorsic, Kevin P. White, M. Eileen Dolan, Christopher D. Brown, Amy L. Stark, Lida Anita To, Daniel F. Gill, Ronald J. Hause, Shan S. Wong, Jamie Myers, Richard B. Jones
Publikováno v:
The American Journal of Human Genetics. 95(2):194-208
Many genetic variants associated with human disease have been found to be associated with alterations in mRNA expression. Although it is commonly assumed that mRNA expression changes will lead to consequent changes in protein levels, methodological c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5581be26eade9521ca1c5ee02441fc
Autor:
Lidija K. Gorsic, M. Eileen Dolan, Hae Kyung Im, Uchenna O. Njiaju, Eric R. Gamazon, Heather E. Wheeler, Shannon M. Delaney
Publikováno v:
Pharmacogenetics and Genomics. 22:498-507
The clinical use of paclitaxel is limited by variable responses and the potential for significant toxicity. To date, studies of associations between variants in candidate genes and paclitaxel effects have yielded conflicting results. We aimed to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0303ce2998051bad806604326f8907b5
https://doi.org/10.1097/fpc.0b013e328352f436
https://doi.org/10.1097/fpc.0b013e328352f436