Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lidia V. Starostenko"'
Autor:
Vladimir V. Koval, Nadejda I. Rechkunova, Olga I. Lavrik, Alexander A. Lomzov, N. A. Lebedeva, Lidia V. Starostenko
Publikováno v:
DNA Repair. 50:43-53
The major enzyme in eukaryotic cells that catalyzes the cleavage of apurinic/apyrimidinic (AP or abasic) sites is AP endonuclease 1 (APE1) that cleaves the phosphodiester bond on the 5'-side of AP sites. We found that the efficiency of AP site cleava
Autor:
Olga I. Lavrik, Nadejda I. Rechkunova, Alexander Kolbanovskiy, Nicholas E. Geacintov, N. A. Lebedeva, Lidia V. Starostenko
Publikováno v:
DNA Repair. 24:1-9
The combined action of oxidative stress and genotoxic polycyclic aromatic hydrocarbons derivatives can lead to cluster-type DNA damage that includes both a modified nucleotide and a bulky lesion. As an example, we investigated the possibility of repa