Výsledky vyhledávání - "Lidia Urbina"

Akademický článek

P2X7 Receptor-Related Genetic Mouse Models – Tools for Translational Research in Psychiatry

Autor: Lidia Urbina-Treviño, Iven-Alex von Mücke-Heim, Jan M. Deussing

Publikováno v: Frontiers in Neural Circuits, Vol 16 (2022)

Depression is a common psychiatric disorder and the leading cause of disability worldwide. Although treatments are available, only about 60% of treated patients experience a significant improvement in disease symptoms. Numerous clinical and rodent st

Externí odkaz: https://doaj.org/article/53d16aebcc8345e9b40246e2ec8aafa3

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Introducing a depression-like syndrome for translational neuropsychiatry: a plea for taxonomical validity and improved comparability between humans and mice

Autor: Iven-Alex von Mücke-Heim, Lidia Urbina-Treviño, Joeri Bordes, Clemens Ries, Mathias V. Schmidt, Jan M. Deussing

Publikováno v: Molecular psychiatry. 28(1)

Depressive disorders are the most burdensome psychiatric disorders worldwide. Although huge efforts have been made to advance treatment, outcomes remain unsatisfactory. Many factors contribute to this gridlock including suboptimal animal models. Espe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef06af16e17290d46ec0894cb529bbd2
https://pubmed.ncbi.nlm.nih.gov/36104436

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Involvement of Autophagy in Levodopa‐Induced Dyskinesia

Autor: Carina Plewnia, Lidia Urbina, David Sulzer, Erwan Bezard, Mikael Altun, Michael Feyder, Benjamin Dehay, Anders Borgkvist, Per Nilsson, Qin Li, Giada Spigolon, Emanuela Santini, Alessandro Piccin, Gilberto Fisone, Ori J. Lieberman

Publikováno v: Movement Disorders
Movement Disorders, Wiley, 2021, Online ahead of print. ⟨10.1002/mds.28480⟩
Movement Disorders, 2021, Online ahead of print. ⟨10.1002/mds.28480⟩

Background Autophagy is intensively studied in cancer, metabolic and neurodegenerative diseases, but little is known about its role in pathological conditions linked to altered neurotransmission. We examined the involvement of autophagy in levodopa (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db06734382d3407f323778ea9b5f0938
https://www.hal.inserm.fr/inserm-03114552/document

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Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model

Autor: Antonio Ramírez-Fernández, Lidia Urbina-Treviño, Giorgia Conte, Mariana Alves, Björn Rissiek, Anna Durner, Nicolas Scalbert, Jiong Zhang, Tim Magnus, Friedrich Koch-Nolte, Nikolaus Plesnila, Jan M. Deussing, Tobias Engel, Robin Kopp, Annette Nicke

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)

The ATP-gated P2X7 receptor is highly expressed in microglia and has been involved in diverse brain diseases. P2X7 effects were also described in neurons and astrocytes but its localisation and function in these cell types has been challenging to dem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::06e41fb7e8cab3f200631e2fd98a30fe
http://europepmc.org/articles/PMC7669894

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