Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lidia Tardio"'
Autor:
A. Larrañaga-Vera, Raquel Largo, Lidia Tardio, C. Rodriguez-Villar, Gabriel Herrero-Beaumont, Natasha E. Zachara, J. Andres-Bergos
Publikováno v:
Osteoarthritis and Cartilage. 22(2):259-263
Summary Objective There is increasing evidence that the addition of O-linked N-acetylglucosamine (O-GlcNAc) to proteins plays an important role in cell signaling pathways. In chondrocytes, accumulation of O-GlcNAc-modified proteins induces hypertroph
Autor:
Sergio Portal-Núñez, P. Gratal, Jorge A. Roman-Blas, Raquel Largo, Gabriel Herrero-Beaumont, Aránzazu Mediero, Lidia Tardio
Publikováno v:
European journal of pharmacology. 794
Osteoarthritis is the most common chronic joint disorder especially during aging. Although with controversies, glucosamine, both in its forms of sulfate and hydrochloride, and chondroitin sulfate are commonly employed to treat osteoarthritis. Due to
Autor:
Rodolfo Gómez, A. Larrañaga-Vera, Raquel Largo, Lidia Tardio, Gabriel Herrero-Beaumont, J. Andres-Bergos
Publikováno v:
The Journal of biological chemistry. 287(40)
Insulin is an inducer of chondrocyte hypertrophy and growth plate chondrogenesis, although the specific molecular mechanisms behind these effects are mostly unknown. Our aim was to investigate whether insulin-induced chondrocyte hypertrophy occurs th
Autor:
Raquel Largo, M.J. Martínez-Calatrava, Jorge A. Roman-Blas, I. Prieto-Potin, Gabriel Herrero-Beaumont, Lidia Tardio
Publikováno v:
Scopus-Elsevier
The receptor activator nuclear factor-kappaB ligand (RANKL) diffuses from articular cartilage to subchondral bone. However, the role of chondrocyte-synthesized RANKL in rheumatoid arthritis-associated juxta-articular bone loss has not yet been explor
Autor:
Juan Moreno-Rubio, Gabriel Herrero-Beaumont, Lidia Tardio, M. Angeles Alvarez-Soria, Raquel Largo
Publikováno v:
Arthritis and rheumatism. 62(2)
Objective Although the osteoprotegerin (OPG)/RANK/RANKL system is the main modulator of bone remodeling, it remains unclear whether it is regulated in cartilage during osteoarthritis (OA). The aim of this study was to examine whether nonsteroidal ant
Autor:
I. Prieto-Potin, Jorge A. Roman-Blas, Lidia Tardio, Raquel Largo, M.J. Martínez-Calatrava, Gabriel Herrero-Beaumont
Publikováno v:
Osteoarthritis and Cartilage. 20:S65-S66
Publikováno v:
Annals of the Rheumatic Diseases. 70:A86-A86
Background and objectives Nuclear and cytoplasmic protein glycosylation by the addition of o-linked n-acetylglucosamine (O-GlcNAc) to serine and threonine residues is a widespread post-translational modification that has been implicated in the regula