Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lidia Nikolaevna Semenkova"'
Autor:
Aleksey Nikolaevich Marchenko, Dmitry I Dudich, Igor Dudich, Elena Dudich, Olga Roslovtceva, Luidmila Khromikh, Elena Vladimirovna Morozkina, Lidia Nikolaevna Semenkova, Sergey Vladimirovich Benevolensky, Sergey Zatcepin, Galina Soboleva, Eduard Borisovich Tatulov
Publikováno v:
Protein Expression and Purification. 84:94-107
Alpha-fetoprotein (AFP) is a biological drug candidate of high medicinal potential in the treatment of autoimmune diseases, cancer, and regenerative medicine. Large-scale production of recombinant human alpha-fetoprotein (rhAFP) is desirable for stru
Autor:
Timo Korpela, Alexander I. Denesyuk, Edward Borisovitch Tatulov, Lidia Nikolaevna Semenkova, Igor Dudich, Elena Dudich
Publikováno v:
FEBS Journal. 273:3837-3849
Previous results have shown that the human oncoembryonic protein alpha-fetoprotein (AFP) induces dose-dependent targeting apoptosis in tumor cells, accompanied by cytochrome c release and caspase 3 activation. AFP positively regulates cytochrome c/dA
Autor:
Timo Korpela, Igor Dudich, Natalie Tokhtamisheva, Elena Dudich, Juan-Antonio Palop-Cubillo, Yury Okruzhnov, Edward Borisovitch Tatulov, Lidia Nikolaevna Semenkova, Jesús García-Foncillas
Publikováno v:
European Journal of Biochemistry. 270:4388-4399
Previous results have shown that the oncoembryonic marker α-fetoprotein (AFP) is able to induce apoptosis in tumor cells through activation of caspase 3, bypassing Fas-dependent and tumor necrosis factor receptor-dependent signaling. In this study w
Autor:
M. A. Nikolaeva, Edward Borisovitch Tatulov, Lidia Nikolaevna Semenkova, I.V. Dudich, Natasha Tochtamisheva, E.A. Gorbatova, Gennady T. Sukhikh, Elena Dudich
Publikováno v:
European Journal of Biochemistry. 266:750-761
alpha-Fetoprotein (AFP) is an oncoembryonal protein with multiple cell growth regulating, differentiating and immunosuppressive activities. Previous studies have shown that treatment of tumor cells in vitro with 1-10 microM AFP produces significant s
Autor:
Natasha Tokhtamysheva, Elena Dudich, Lidia Nikolaevna Semenkova, Igor Dudich, Timo Korpela, Jukka Hellman
Publikováno v:
Biochemistry. 38:10406-10414
Short-time limited peptic hydrolysis of ligand-free human alpha-fetoprotein (AFP) gave two main fragments with molecular masses of 38 and 32 kDa, which had been produced by splitting of the molecule at the position Leu(312)-Asn(313). A more prolonged