Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lidia M. Lima"'
Autor:
Hygor M. R. de Souza, Jéssica S. Guedes, Rosana H. C. N. Freitas, Luis G. V. Gelves, Harold H. Fokoue, Carlos Mauricio R. Sant’Anna, Eliezer J. Barreiro, Lidia M. Lima
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 718-727 (2022)
Esters are one of the major functional groups present in the structures of prodrugs and bioactive compounds. Their presence is often associated with hydrolytic lability. In this paper, we describe a comparative chemical and biological stability of ho
Externí odkaz:
https://doaj.org/article/fbb8bd8c8d3b4bd2995cecac8995a8b1
Autor:
Antonio Monge, Ignacio Aldana, Silvia Pérez-Silanes, Beatriz Solano, Esther Vicente, Lidia M. Lima
Publikováno v:
Molecules, Vol 13, Iss 1, Pp 78-85 (2008)
The unexpected tendency of amines and functionalized hydrazines to reduceethyl 3-phenylquinoxaline-2-carboxylate 1,4-di-N-oxide (1) to afford a quinoxaline 1c andmono-oxide quinoxalines 1a and 1b is described. The experimental conditions werestandard
Externí odkaz:
https://doaj.org/article/38763faef7294ed4a15b921764dea5d5
Autor:
Gisele A Padilha, Isabela eHenriques, Miqueias eLopes-Pacheco, Soraia C Abreu, Milena V Oliveira, Marcelo M Morales, Lidia M Lima, Eliezer Jesus Barreiro, Pedro L Silva, Debora G Xisto, Patricia Rieken Macedo Rocco
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Emphysema is an intractable pulmonary disease characterized by an inflammatory process of the airways and lung parenchyma and ongoing remodeling process in an attempt to restore lung structure. There is no effective drug therapy that regenerates lung
Externí odkaz:
https://doaj.org/article/d9fb44f3cf7a471f86461800f35e0285
Autor:
Juliana Vaz Bevilaqua, Lidia M. Lima, Aline Gomes Cunha, Eliezer J. Barreiro, Tito L. M. Alves, Lucia Moreira Campos Paiva, Denise M. Guimarães Freire
Publikováno v:
Twenty-Sixth Symposium on Biotechnology for Fuels and Chemicals ISBN: 9781588296979
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::223c3a408fe9fa927591fb303841b27b
https://doi.org/10.1007/978-1-59259-991-2_11
https://doi.org/10.1007/978-1-59259-991-2_11
Autor:
Natália M. de Lima, Lidia M. Lima
Publikováno v:
Revista Virtual de Química. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5135dc3e770d0831116f5e49ac8f4815
https://doi.org/10.5935/1984-6835.20090006
https://doi.org/10.5935/1984-6835.20090006
Autor:
Daniela R. de Oliveira, Rodolfo C. Maia, Patrícia R. de Carvalho França, Patrícia D. Fernandes, Gisele Barbosa, Lídia M. Lima, Carlos A. Manssour Fraga
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1519 (2022)
Among the most recent proposals regarding the mechanism of action of dipyrone, the modulation of cannabinoid receptors CB1 and CB2 appears to be a promising hypothesis. In this context, the present work describes a series of five novel pyrazolamides
Externí odkaz:
https://doaj.org/article/0d9638ca095f4a7cab99181f466a68bc
Autor:
Lídia M. Lima
Publikováno v:
Química Nova, Vol 30, Iss 6, Pp 1456-1468 (2007)
The main aspects of the modern Medicinal Chemistry, among the classic and industrial paradigms, used in the drug discovery process will be treated. The contribution of the Brazilian science in the knowledge generation in Medicinal Chemistry will be d
Externí odkaz:
https://doaj.org/article/38508e1c85a945dba1858bb9bdd9e913
Autor:
SONJA HERRMANN, TABEA SCHÜBEL, FANNY N. COSTA, MARIA LETÍCIA C. BARBOSA, FABIO F. FERREIRA, THAYS L.M.F. DIAS, MORGANA V. ARAÚJO, MAGNA S. ALEXANDRE-MOREIRA, LÍDIA M. LIMA, STEFAN LAUFER, ELIEZER J. BARREIRO
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 90, Iss 1 suppl 2, Pp 1073-1088
ABSTRACT N-acylhydrazone is an interesting privileged structure that has been used in the molecular design of a myriad of bioactive compounds. In order to identify new antinociceptive drug candidates, we described herein the design, synthesis, X-ray
Externí odkaz:
https://doaj.org/article/5dd820533ab14341be47b5e7039d9045