Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lidia Luzhna"'
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Ionizing radiation is a well-established cause of deleterious effects on human health. Understanding the risks of radiation exposure is important for the development of protective measures and guidelines. Demographic factors such as age, sex, genetic
Externí odkaz:
https://doaj.org/article/3f3f998fc7644042ba9dd4d545bea9c2
Publikováno v:
Oncoscience
The successful treatment of cancer, including breast cancer, depends largely on radiation therapy and proper diagnostics. The effect of ionizing radiation on cells and tissues depends on the radiation dose and energy level, but there is insufficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e47bca499b70cf67b8b629742410a0
https://doi.org/10.18632/oncoscience.298
https://doi.org/10.18632/oncoscience.298
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 779:39-56
Rats are excellent experimental models for studying breast cancer, but rat strains differ in susceptibility. Among the four strains used in this study, Fischer rats are less susceptible to spontaneous breast cancer, yet they are highly prone to extre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2dc3d00fb7e4e13696ed3cecd16b80e
https://doi.org/10.1016/j.mrgentox.2014.07.006
https://doi.org/10.1016/j.mrgentox.2014.07.006
Autor:
Olga Kovalchuk, Lidia Luzhna
Effective breast cancer management and decreasing breast cancer fatalities is contingent upon reliable diagnostic procedures and treatment modalities, including those based on ionizing radiation. On the one hand, ionizing radiation is widely used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330a0031cfeff3c44e230525b8968ced
https://europepmc.org/articles/PMC4968965/
https://europepmc.org/articles/PMC4968965/
Autor:
Olga Kovalchuk, Lidia Luzhna
Publikováno v:
Oncoscience
Ionizing radiation has been successfully used in medical tests and treatment therapies for a variety of medical conditions. However, patients and health-care workers are greatly concerned about overexposure to medical ionizing radiation and possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9613c32498c102628ab4c3491acf80b
https://pubmed.ncbi.nlm.nih.gov/25594002
https://pubmed.ncbi.nlm.nih.gov/25594002
Publikováno v:
Genes & Cancer
It is known that cellular stresses such as ionizing radiation activate LINE-1 (long interspersed nuclear element type 1, L1), but the molecular mechanisms of LINE-1 activation have not been fully elucidated. There is a possibility that DNA methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6b9578f36ac5ad2f04b1a022224867
https://pubmed.ncbi.nlm.nih.gov/25821563
https://pubmed.ncbi.nlm.nih.gov/25821563
Publikováno v:
International journal of oncology. 42(5)
A positive response to breast cancer treatment is largely dependent on the successful combination of anticancer treatment modalities, such as chemotherapy and radiation therapy. Unfortunately, chemotherapy resistance occurs frequently. Furthermore, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498fcec2d896df4b3549b93d001f0d5d
https://pubmed.ncbi.nlm.nih.gov/23467667
https://pubmed.ncbi.nlm.nih.gov/23467667
Autor:
Olga Kovalchuk, Lidia Luzhna
Publikováno v:
Biochemical and biophysical research communications. 392(2)
Chemoresistant tumors often fail to respond to other cytotoxic treatments such as radiation therapy. The mechanisms of chemo- and radiotherapy cross resistance are not fully understood and are believed to be epigenetic in nature. We hypothesize that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07884514f0e2f2f576ce3b644953552
https://pubmed.ncbi.nlm.nih.gov/20034463
https://pubmed.ncbi.nlm.nih.gov/20034463