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Akademický článek

The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structures.

Autor: Neal F Lue, Ruobo Zhou, Lidia Chico, Ninghui Mao, Olga Steinberg-Neifach, Taekjip Ha

Publikováno v: PLoS Genetics, Vol 9, Iss 1, p e1003145 (2013)

The telomere-ending binding protein complex CST (Cdc13-Stn1-Ten1) mediates critical functions in both telomere protection and replication. We devised a co-expression and affinity purification strategy for isolating large quantities of the complete Ca

Externí odkaz: https://doaj.org/article/9a6f03101a044b55859f557f35b79a2a

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Akademický článek

The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination.

Autor: Lidia Chico, Toni Ciudad, Min Hsu, Neal F Lue, Germán Larriba

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23732 (2011)

The heterodimeric Ku complex has been shown to participate in DNA repair and telomere regulation in a variety of organisms. Here we report a detailed characterization of the function of Ku70 in the diploid fungal pathogen Candida albicans. Both ku70

Externí odkaz: https://doaj.org/article/a6a023e3682d4b13a61607351dc3c509

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Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA

Autor: Wei-Feng Yen, Neal F. Lue, Lidia Chico, Ming Lei

Publikováno v: Proceedings of the National Academy of Sciences. 108:20370-20375

The yeast telomerase regulatory protein Est3 is required for telomere maintenance in vivo, and shares intriguing structural and functional similarities with the mammalian telomeric protein TPP1. Here we report our physical and functional characteriza

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5fc303e4a8bde596ef348ecfff2fce9
https://doi.org/10.1073/pnas.1017855108

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Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs

Autor: Paul Smith, Stewart Shuman, Beate Schwer, Lidia Chico, Agata Jacewicz

Saccharomyces cerevisiae Msl5 orchestrates spliceosome assembly by binding the intron branchpoint sequence 5′-UACUAAC and, with its heterodimer partner protein Mud2, establishing cross intron-bridging interactions with the U1 snRNP at the 5′ spli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955385e9181b7004ce4eb6656e80f9b4
https://europepmc.org/articles/PMC4338336/

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The Candida albicans Ku70 modulates telomere length and structure by regulating both telomerase and recombination

Autor: Min Hsu, Toni Ciudad, Germán Larriba, Neal F. Lue, Lidia Chico

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23732 (2011)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c780329fef2b59ea6bc10b35ac57e872
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21886818/?tool=EBI

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The Telomere Capping Complex CST Has an Unusual Stoichiometry, Makes Multipartite Interaction with G-Tails, and Unfolds Higher-Order G-Tail Structures

Autor: Olga Steinberg-Neifach, Taekjip Ha, Ruobo Zhou, Neal F. Lue, Lidia Chico, Ninghui Mao

Publikováno v: PLoS Genetics, Vol 9, Iss 1, p e1003145 (2013)
PLoS Genetics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d780062c5b0248d8174581ace271b20f
https://doi.org/10.1371/journal.pgen.1003145

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