Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lidia Chellini"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Prostate cancer (PC) is the most commonly diagnosed male malignancy and an important cause of mortality. Androgen deprivation therapy is the first line treatment but, unfortunately, a large part of patients evolves to a castration
Externí odkaz:
https://doaj.org/article/6fcf3d6ec18c436d931eae4115fb6a7e
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-10 (2020)
Abstract In-depth analysis of global RNA sequencing has enabled a comprehensive overview of cellular transcriptomes and revealed the pervasive transcription of divergent RNAs from promoter regions across eukaryotic genomes. These studies disclosed th
Externí odkaz:
https://doaj.org/article/7334ac6dfdd346e99f033f8eebfe0e46
Autor:
Teresa Giannattasio, Erika Testa, Ramona Palombo, Lidia Chellini, Flavia Franceschini, Álvaro Crevenna, Petko M. Petkov, Maria Paola Paronetto, Marco Barchi
Publikováno v:
Cellular and Molecular Life Sciences. 80
In mammals, meiotic recombination is initiated by the introduction of DNA double strand breaks (DSBs) into narrow segments of the genome, defined as hotspots, which is carried out by the SPO11/TOPOVIBL complex. A major player in the specification of
Autor:
Teresa Giannattasio, Erika Testa, Ramona Palombo, Lidia Chellini, Álvaro Crevenna, Petko Petkov, Maria Paola Paronetto, Marco Barchi
In mammals, meiotic recombination is initiated by the introduction of DNA double strand breaks (DSBs) into narrow segments of the genome, defined as hotspots, which is carried out by the SPO11/TOPOVIBL complex. A major player in hotspots specificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1c7b1b415ae070ee3947e8788bc314
https://doi.org/10.21203/rs.3.rs-2139086/v1
https://doi.org/10.21203/rs.3.rs-2139086/v1
Publikováno v:
Cancers. 14(19)
Sarcomas comprise a heterogeneous group of rare mesenchymal malignancies. Sarcomas can be grouped into two categories characterized by different prognosis and treatment approaches: soft tissue sarcoma and primary bone sarcoma. In the last years, rese
Autor:
Anna Bagnato, Valentina Caprara, Laura Rosanò, Rosanna Sestito, Francesca Spadaro, Lidia Chellini
Publikováno v:
Matrix biology
81 (2019): 17–33. doi:10.1016/j.matbio.2018.10.005
info:cnr-pdr/source/autori:Chellini, Lidia; Caprara, Valentina; Spadaro, Francesca; Sestito, Rosanna; Bagnato, Anna; Rosano, Laura/titolo:Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer/doi:10.1016%2Fj.matbio.2018.10.005/rivista:Matrix biology (Print)/anno:2019/pagina_da:17/pagina_a:33/intervallo_pagine:17–33/volume:81
81 (2019): 17–33. doi:10.1016/j.matbio.2018.10.005
info:cnr-pdr/source/autori:Chellini, Lidia; Caprara, Valentina; Spadaro, Francesca; Sestito, Rosanna; Bagnato, Anna; Rosano, Laura/titolo:Regulation of extracellular matrix degradation and metastatic spread by IQGAP1 through endothelin-1 receptor signalling in ovarian cancer/doi:10.1016%2Fj.matbio.2018.10.005/rivista:Matrix biology (Print)/anno:2019/pagina_da:17/pagina_a:33/intervallo_pagine:17–33/volume:81
The invasive phenotype of serous ovarian cancer (SOC) cells is linked to the formation of actin-based protrusions, invadopodia, operating extracellular matrix (ECM) degradation and metastatic spread. Growth factor receptors might cause engagement of
Autor:
Lidia Chellini, Laura Rosanò, Ilenia Masi, Valentina Caprara, Alberto Rainer, Francesca Spadaro, Andrea Zancla, Rosanna Sestito, Anna Bagnato
Publikováno v:
Cell reports. 34(9)
Summary Cancer cells use actin-based membrane protrusions, invadopodia, to degrade stroma and invade. In serous ovarian cancer (SOC), the endothelin A receptor (ETAR) drives invadopodia by a not fully explored coordinated function of β-arrestin1 (β
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-10 (2020)
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-10 (2020)
In-depth analysis of global RNA sequencing has enabled a comprehensive overview of cellular transcriptomes and revealed the pervasive transcription of divergent RNAs from promoter regions across eukaryotic genomes. These studies disclosed that genome
Autor:
Alberto Rainer, Lidia Chellini, Ilenia Masi, Rosanna Sestito, Andrea Zancla, Valentina Caprara, Anna Bagnato, Laura Rosanò, Francesca Spadaro
Publikováno v:
Cancer Research. 81:LT003-LT003
During the metastatic progression, invading cells might achieve degradation and invasion into the extracellular matrix (ECM) using invadopodia, actin-based protrusions. Several growth factors, among other stimuli, might induce invadopodia, generating
Autor:
Anna Bagnato, Gabriella Ferrandina, Andrea Sacconi, Francesca Spadaro, Giovanni Blandino, Lidia Chellini, Francesca Di Modugno, Piera Tocci, Valentina Caprara, Paola Nisticò, Laura Rosanò
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 115 (2018): 3132–3137. doi:10.1073/pnas.1715998115
info:cnr-pdr/source/autori:Di Modugno, Francesca; Caprara, Valentina; Chellini, Lidia; Tocci, Piera; Spadaro, Francesca; Ferrandina, Gabriella; Sacconi, Andrea; Blandino, Giovanni; Nistico, Paola; Bagnato, Anna; Rosano, Laura/titolo:hMENA is a key regulator in endothelin-1%2Fbeta-arrestin1-induced invadopodial function and metastatic process/doi:10.1073%2Fpnas.1715998115/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2018/pagina_da:3132/pagina_a:3137/intervallo_pagine:3132–3137/volume:115
info:cnr-pdr/source/autori:Di Modugno, Francesca; Caprara, Valentina; Chellini, Lidia; Tocci, Piera; Spadaro, Francesca; Ferrandina, Gabriella; Sacconi, Andrea; Blandino, Giovanni; Nistico, Paola; Bagnato, Anna; Rosano, Laura/titolo:hMENA is a key regulator in endothelin-1%2Fbeta-arrestin1-induced invadopodial function and metastatic process/doi:10.1073%2Fpnas.1715998115/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2018/pagina_da:3132/pagina_a:3137/intervallo_pagine:3132–3137/volume:115
Aberrant activation of endothelin-1 receptors (ET-1R) elicits pleiotropic effects relevant for tumor progression. The network activated by this receptor might be finely, spatially, and temporarily orchestrated by beta-arrestin1 (beta-arr1)-driven int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f8f19532d214cc5f5383bccd72a802
http://hdl.handle.net/10807/122318
http://hdl.handle.net/10807/122318