Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lidia C. Sambucetti"'
Autor:
Stacy W. Remiszewski, Lidia C. Sambucetti, Kenneth W. Bair, John Bontempo, David Cesarz, Nagarajan Chandramouli, Ru Chen, Min Cheung, Susan Cornell-Kennon, Karl Dean, George Diamantidis, Dennis France, Michael A. Green, Kobporn Lulu Howell, Rina Kashi, Paul Kwon, Peter Lassota, Mary S. Martin, Yin Mou, Lawrence B. Perez, Sushil Sharma, Troy Smith, Eric Sorensen, Francis Taplin, Nancy Trogani, Richard Versace, Heather Walker, Susan Weltchek-Engler, Alexander Wood, Arthur Wu, Peter Atadja
Publikováno v:
Journal of Medicinal Chemistry. 46:4609-4624
A series of N-hydroxy-3-phenyl-2-propenamides were prepared as novel inhibitors of human histone deacetylase (HDAC). These compounds were potent enzyme inhibitors, having IC50s < 400 nM in a partially purified enzyme assay. However, potency in cell g
Autor:
Nancy Trogani, Paul Kwon, Kobporn Lulu Howell, Manfred Jung, Peter Wisdom Atadja, Kenneth W. Bair, Michael A. Green, Wendy D. Cornell, Heather Walker, Stacy W. Remiszewski, Lidia C. Sambucetti
Publikováno v:
Journal of Medicinal Chemistry. 45:753-757
Inhibitors of histone deacetylase (HDAC) have been shown to induce terminal differentiation of human tumor cell lines and to have antitumor effects in vivo. We have prepared analogues of suberoylanilide hydroxamic acid (SAHA) and trichostatin A and h
Autor:
Stacy W, Remiszewski, Lidia C, Sambucetti, Kenneth W, Bair, John, Bontempo, David, Cesarz, Nagarajan, Chandramouli, Ru, Chen, Min, Cheung, Susan, Cornell-Kennon, Karl, Dean, George, Diamantidis, Dennis, France, Michael A, Green, Kobporn Lulu, Howell, Rina, Kashi, Paul, Kwon, Peter, Lassota, Mary S, Martin, Yin, Mou, Lawrence B, Perez, Sushil, Sharma, Troy, Smith, Eric, Sorensen, Francis, Taplin, Nancy, Trogani, Richard, Versace, Heather, Walker, Susan, Weltchek-Engler, Alexander, Wood, Arthur, Wu, Peter, Atadja
Publikováno v:
Journal of medicinal chemistry. 46(21)
A series of N-hydroxy-3-phenyl-2-propenamides were prepared as novel inhibitors of human histone deacetylase (HDAC). These compounds were potent enzyme inhibitors, having IC(50)s400 nM in a partially purified enzyme assay. However, potency in cell gr
Autor:
Ivette C. Piña, Jeffrey T. Gautschi, Gui-Yang-Sheng Wang, Miranda L. Sanders, Francis J. Schmitz, Dennis France, Susan Cornell-Kennon, Lidia C. Sambucetti, Stacy W. Remiszewski, Larry B. Perez, Kenneth W. Bair, Phillip Crews
Publikováno v:
The Journal of organic chemistry. 68(10)
Four novel bisulfide bromotyrosine derivatives, psammaplins E (9), F (10), G (11), and H (12), and two new bromotyrosine derivatives, psammaplins I (13) and J (14), were isolated from the sponge Pseudoceratina purpurea, along with known psammaplins A
Publikováno v:
Cell. 52:471-480
The adipocyte P2 (aP2) gene contains a regulatory element, FSE2, that functions during adipocyte differentiation and binds a protein complex containing the product of the fos proto-oncogene (Fos). We show here that the quantitative and qualitative na
Publikováno v:
Gene. 43:69-77
To investigate the properties of the fos oncogene, we have constructed bacterial and yeast vectors which express the entire fos -coded protein (Fos) and two C-terminal deletion products. In Escherichia coli , Fos proteins were expressed from the phag
Publikováno v:
Journal of Molecular Biology. 161:13-31
DNA donor activity and surface exclusion of Escherichia coli F + and Hfr strains require expression of both F-plasmid and chromosomal genes. The plasmid genes are contained in the 35,000 base tra region, where most of them are organized as a co-regul
Autor:
Lidia C. Sambucetti, Robert A. Bender
Publikováno v:
Moleculargeneral genetics : MGG. 189(2)
Klebsiella aerogenes recombinants resulting from bacteriophage P1-mediated generalized transduction failed to increase in number for approximately six generations after transduction. Nevertheless these recombinants continued to grow and became sensit
Autor:
Lidia C. Sambucetti, Tom Curran
Publikováno v:
Science (New York, N.Y.). 234(4782)
The properties of the viral and cellular fos proteins (Fos) were investigated as a first step toward understanding the function of the fos gene. Treatment of nuclei with salt and nonionic detergents solubilized a complex that contained Fos together w