Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lidia, Vasiljeva"'
Autor:
Sina Wittmann, Max Renner, Beth R. Watts, Oliver Adams, Miles Huseyin, Carlo Baejen, Kamel El Omari, Cornelia Kilchert, Dong-Hyuk Heo, Tea Kecman, Patrick Cramer, Jonathan M. Grimes, Lidia Vasiljeva
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Termination of RNA polymerase II is a critical step in transcription. Here, the authors provide evidence that the fission yeast CID-RRM protein Seb1 is required for termination of coding and non-coding genes through interaction with both the polymera
Externí odkaz:
https://doaj.org/article/ef394db5756b48a9bb4c2015dc21a112
Autor:
Cornelia Kilchert, Sina Wittmann, Monica Passoni, Sneha Shah, Sander Granneman, Lidia Vasiljeva
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2504-2515 (2015)
In eukaryotic cells, inefficient splicing is surprisingly common and leads to the degradation of transcripts with retained introns. How pre-mRNAs are committed to nuclear decay is unknown. Here, we uncover a mechanism by which specific intron-contain
Externí odkaz:
https://doaj.org/article/0660579b8e4e4b9fbf3b30c671d65e30
Autor:
Tea Kecman, Krzysztof Kuś, Dong-Hyuk Heo, Katie Duckett, Adrien Birot, Sabrina Liberatori, Shabaz Mohammed, Lucia Geis-Asteggiante, Carol V. Robinson, Lidia Vasiljeva
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 259-269.e5 (2018)
Summary: Termination of RNA polymerase II (Pol II) transcription is a key step that is important for 3′ end formation of functional mRNA, mRNA release, and Pol II recycling. Even so, the underlying termination mechanism is not yet understood. Here,
Externí odkaz:
https://doaj.org/article/3caa5739608f43eb8617adce3984345a
Autor:
Nikolay Zenkin, Tea Kecman, Søren Nielsen, Krzysztof Kuś, Dong-Hyuk Heo, Adrien Birot, Pawel Grzechnik, Sue Mei Tan-Wong, Lidia Vasiljeva
Publikováno v:
Cell Reports
Heo, D H, Kuś, K, Grzechnik, P, Tan-Wong, S M, Birot, A, Kecman, T, Nielsen, S, Zenkin, N & Vasiljeva, L 2021, ' Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription ', Cell Reports, vol. 36, no. 10, 109671 . https://doi.org/10.1016/j.celrep.2021.109671
Heo, D H, Kuś, K, Grzechnik, P, Tan-Wong, S M, Birot, A, Kecman, T, Nielsen, S, Zenkin, N & Vasiljeva, L 2021, ' Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription ', Cell Reports, vol. 36, no. 10, 109671 . https://doi.org/10.1016/j.celrep.2021.109671
Summary Phosphorylation of the RNA polymerase II C-terminal domain Y1S2P3T4S5P6S7 consensus sequence coordinates key events during transcription, and its deregulation leads to defects in transcription and RNA processing. Here, we report that the hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752e94ffdeea97dd844ab3b0f80c0038
http://europepmc.org/articles/PMC8441049
http://europepmc.org/articles/PMC8441049
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65606 (2013)
A key question in the field of RNA regulation is how some exosome substrates, such as spliceosomal snRNAs and telomerase RNA, evade degradation and are processed into stable, functional RNA molecules. Typical feature of these non-coding RNAs is prese
Externí odkaz:
https://doaj.org/article/e9c4e8628b8f457898d7b2282f92458c
Autor:
Cornelia, Kilchert, Tea, Kecman, Emily, Priest, Svenja, Hester, Ebru, Aydin, Krzysztof, Kus, Oliver, Rossbach, Alfredo, Castello, Shabaz, Mohammed, Lidia, Vasiljeva
Publikováno v:
Genome Res
Large RNA-binding complexes play a central role in gene expression and orchestrate production, function, and turnover of mRNAs. The accuracy and dynamics of RNA–protein interactions within these molecular machines are essential for their function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9940057ba38a6579dadcec52144d26f0
https://pubmed.ncbi.nlm.nih.gov/32554781
https://pubmed.ncbi.nlm.nih.gov/32554781
Autor:
Svenja Hester, Krzysztof Kus, Cornelia Kilchert, Emily Priest, Ebru Aydin, Lidia Vasiljeva, Alfredo Castello, Oliver Rossbach, Tea Kecman, Shabaz Mohammed
Large RNA-binding complexes play a central role in gene expression and orchestrate production, function, and turnover of mRNAs. The accuracy and dynamics of RNA–protein interactions within these molecular machines are essential for their function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ef71188ccb20b10ec41d6dd22f34bb
https://doi.org/10.1101/748194
https://doi.org/10.1101/748194
Publikováno v:
Methods in enzymology. 612
The RNA polymerase II carboxyl-terminal domain (CTD) consists of tandem repeats of consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Dynamic posttranslational modifications of the CTD generate a CTD code crucial for the cotranscriptional recruit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c785e535be140bfa4dfdd1187f30d7e
https://pubmed.ncbi.nlm.nih.gov/30502955
https://pubmed.ncbi.nlm.nih.gov/30502955
Publikováno v:
Nature Reviews Molecular Cell Biology. 17:227-239
The RNA exosome complex is the most versatile RNA-degradation machine in eukaryotes. The exosome has a central role in several aspects of RNA biogenesis, including RNA maturation and surveillance. Moreover, it is emerging as an important player in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2054ec4cef3aa0a40de772c79ea49613
https://doi.org/10.1038/nrm.2015.15
https://doi.org/10.1038/nrm.2015.15
Autor:
Beth R, Watts, Sina, Wittmann, Maxime, Wery, Camille, Gautier, Krzysztof, Kus, Adrien, Birot, Dong-Hyuk, Heo, Cornelia, Kilchert, Antonin, Morillon, Lidia, Vasiljeva
Publikováno v:
Nucleic Acids Research
It is important to accurately regulate the expression of genes involved in development and environmental response. In the fission yeast Schizosaccharomyces pombe, meiotic genes are tightly repressed during vegetative growth. Despite being embedded in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f0951852644c73a4009602e02e3b0a3
https://pubmed.ncbi.nlm.nih.gov/29618061
https://pubmed.ncbi.nlm.nih.gov/29618061