Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lide Hu"'
Autor:
Chuanfeng Liu, Lide Hu, Guanyu Dong, Ying Zhang, Edeildo Ferreira da Silva-Júnior, Xinyong Liu, Luis Menéndez-Arias, Peng Zhan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 4715-4732 (2023)
Influenza is an acute respiratory infection caused by influenza viruses (IFV), According to the World Health Organization (WHO), seasonal IFV epidemics result in approximately 3–5 million cases of severe illness, leading to about half a million dea
Externí odkaz:
https://doaj.org/article/ba338528a0f242a1834806a96f944096
Autor:
Xiangyi Jiang, Boshi Huang, Shawn Rumrill, David Pople, Waleed A. Zalloum, Dongwei Kang, Fabao Zhao, Xiangkai Ji, Zhen Gao, Lide Hu, Zhao Wang, Minghui Xie, Erik De Clercq, Francesc X. Ruiz, Eddy Arnold, Christophe Pannecouque, Xinyong Liu, Peng Zhan
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract HIV-1 reverse transcriptase is one of the most attractive targets for the treatment of AIDS. However, the rapid emergence of drug-resistant strains and unsatisfactory drug-like properties seriously limit the clinical application of HIV-1 non
Externí odkaz:
https://doaj.org/article/c38865deec50478fa334e921f6a1050d
Autor:
Xiangkai Ji, Xiangyi Jiang, Chisa Kobayashi, Yujie Ren, Lide Hu, Zhen Gao, Dongwei Kang, Ruifang Jia, Xujie Zhang, Shujie Zhao, Koichi Watashi, Xinyong Liu, Peng Zhan
Publikováno v:
Molecules, Vol 27, Iss 18, p 5987 (2022)
Hepatitis B virus (HBV) capsid protein (Cp) is necessary for viral replication and the maintenance of viral persistence, having become an attractive target of anti-HBV drugs. To improve the water solubility of HBV capsid protein allosteric modulator
Externí odkaz:
https://doaj.org/article/1d9c774993254a6aa2d0692cfebd1d4b
Autor:
Xiangkai Ji, Jing Li, Prem Prakash Sharma, Xiangyi Jiang, Brijesh Rathi, Zhen Gao, Lide Hu, Dongwei Kang, Erik De Clercq, Simon Cocklin, Chuanfeng Liu, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Publikováno v:
Molecules, Vol 27, Iss 18, p 5995 (2022)
As a key structural protein, HIV capsid (CA) protein plays multiple roles in the HIV life cycle, and is considered a promising target for anti-HIV treatment. Based on the structural information of CA modulator PF-74 bound to HIV-1 CA hexamer, 18 nove
Externí odkaz:
https://doaj.org/article/97f7765db41045cbadc4b893f8b9bc68
Autor:
Guanghao Wu, Yanbo Gao, Datao Liu, Xiaoding Tan, Lide Hu, Zidan Qiu, Jingyan Liu, Huidan He, Yanjun Liu
Publikováno v:
ACS Omega, Vol 4, Iss 5, Pp 8834-8845 (2019)
Externí odkaz:
https://doaj.org/article/616a633040b94b0b8fa1891e59567de8
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 3, Pp 645-654 (2013)
Background: Rituximab, a mouse Fab and human Fc chimeric antibody, has been widely used to treat Non-Hodgkin's lymphoma (NHL). However, only 48% of patients respond to the treatment and complete response rate is below 10%. Also, immunogenicity was re
Externí odkaz:
https://doaj.org/article/6d76b1d1220b4edd856d8e29787d00a0
Autor:
Xiangyi Jiang, Prem Prakash Sharma, Brijesh Rathi, Xiangkai Ji, Lide Hu, Zhen Gao, Dongwei Kang, Zhao Wang, Minghui Xie, Shujing Xu, Xujie Zhang, Erik De Clercq, Simon Cocklin, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Publikováno v:
Journal of Medical Virology. 94:5975-5986
Human immunodeficiency virus (HIV) capsid (CA) protein is a promising target for developing novel anti-HIV drugs. Starting from highly anticipated CA inhibitors PF-74, we used scaffold hopping strategy to design a series of novel 1,2,4-triazole pheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb156db7c886743198b168215f00ca1e
https://doi.org/10.1002/jmv.28064
https://doi.org/10.1002/jmv.28064
Publikováno v:
Physical Chemistry Chemical Physics. 24:19927-19937
Bioinspired asymmetric two-dimensional (2D) nanochannels with ionic diode behavior are highly desirable, as they can be constructed and modified easily. However, the knowledge about the rectification mechanism of the nanochannels is still very limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d3da4822881d6624cbe87d25df9f97
https://doi.org/10.1039/d2cp03168j
https://doi.org/10.1039/d2cp03168j
Publikováno v:
Small. :2208079
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9aaaa7377fe0956b1eb03ae55ac34ad
https://doi.org/10.1002/smll.202208079
https://doi.org/10.1002/smll.202208079
Publikováno v:
Indian Journal of Pharmaceutical Sciences.
Although the physical/chemical stability and potential interactions of trastuzumab and pertuzumab in a single infusion bag before co-administration have been evaluated preliminarily, it is not easy to clarify which monoclonal antibodies changes when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27aa2b3e42ba5c73b3826a26a76753fc
https://doi.org/10.36468/pharmaceutical-sciences.775
https://doi.org/10.36468/pharmaceutical-sciences.775