Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Licun, Wu"'
Autor:
Qiulin Huang, Youli Chen, Liyou Lian, Qiqi Lei, Jinfei Chen, Licun Wu, Kari Hemminki, Jianguang Ji, Tianhui Chen
Publikováno v:
Journal of the National Cancer Center, Vol 4, Iss 3, Pp 214-222 (2024)
Objective: To provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China. Methods: Data on patients diagnosed with MM from China during 1990–2019 were obtained from the Global Burden of D
Externí odkaz:
https://doaj.org/article/056efd70ce524bfd93ea40ad71b94aa0
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/621a3e9882054232b575d602e77cb5d5
Autor:
H. S. Jeffrey Man, Vaneeza A. Moosa, Anand Singh, Licun Wu, John T. Granton, Stephen C. Juvet, Chuong D. Hoang, Marc de Perrot
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Awareness of RNA-based therapies has increased after the widespread adoption of mRNA vaccines against SARS-CoV-2 during the COVID-19 pandemic. These mRNA vaccines had a significant impact on reducing lung disease and mortality. They highlighted the p
Externí odkaz:
https://doaj.org/article/28306af162c14f71b1c0bc7bbe5537cf
Autor:
Ananya Hariharan, Weihong Qi, Hubert Rehrauer, Licun Wu, Manuel Ronner, Martin Wipplinger, Jelena Kresoja‐Rakic, Suna Sun, Lucia Oton‐Gonzalez, Marika Sculco, Véronique Serre‐Beinier, Clément Meiller, Christophe Blanquart, Jean‐François Fonteneau, Bart Vrugt, Jan Hendrik Rüschoff, Isabelle Opitz, Didier Jean, Marc dePerrot, Emanuela Felley‐Bosco
Publikováno v:
Molecular Oncology, Vol 16, Iss 22, Pp 3949-3974 (2022)
We previously observed increased levels of adenosine‐deaminase‐acting‐on‐dsRNA (Adar)‐dependent RNA editing during mesothelioma development in mice exposed to asbestos. The aim of this study was to characterize and assess the role of ADAR
Externí odkaz:
https://doaj.org/article/68417b6aa7474f1b8efa6a6d5df04297
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Malignant mesothelioma (MESO) is a highly aggressive cancer with poor prognosis. Epithelial–mesenchymal transition (EMT) is a critical process in malignancies involved in tumor angiogenesis, progression, invasion and metastasis, immunosupp
Externí odkaz:
https://doaj.org/article/843b940267f047e8b4b361c24084f0d5
Autor:
Licun Wu, Marc de Perrot
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1103 (2023)
The SPARC gene plays multiple roles in extracellular matrix synthesis and cell shaping, associated with tumor cell migration, invasion, and metastasis. The SPARC gene is also involved in the epithelial-mesenchymal transition (EMT) process, which is a
Externí odkaz:
https://doaj.org/article/f08987965c584631b90b61b95f5550f3
Autor:
Meilin Chan, Licun Wu, Zhihong Yun, Trevor D. McKee, Michael Cabanero, Yidan Zhao, Mikihiro Kohno, Junichi Murakami, Marc de Perrot
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Chan et al find that the GITR-GITRL pathway is an important mechanism of autocrine proliferation in sarcomatoid mesothelioma that could explain their resistance to therapy. Blocking the GITR-GITRL pathway could therefore be a new therapeutic target f
Externí odkaz:
https://doaj.org/article/3c5ca878a66742d7a38438d115052146
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Carbon nanotubes (CNTs) are nanomaterials with broad applications that are produced on a large scale. Animal experiments have shown that exposure to CNTs, especially one type of multi-walled carbon nanotube, MWCNT-7, can lead to malignant transformat
Externí odkaz:
https://doaj.org/article/6918a5b413a54382928ee475606a69ec
Autor:
Bill T.V. Duong, Licun Wu, Brenda J. Green, Fatemeh Bavaghar-Zaeimi, Zongjie Wang, Mahmoud Labib, Yuxiao Zhou, Fernando J.P. Cantu, Thurgaa Jeganathan, Sandra Popescu, Jennifer Pantea, Marc de Perrot, Shana O. Kelley
Publikováno v:
EBioMedicine, Vol 61, Iss , Pp 103031- (2020)
Background: Malignant pleural mesothelioma (MPM) is an aggressive cancer related to asbestos exposure. Early diagnosis is challenging due to generic symptoms and a lack of biomarkers. We previously demonstrated that mesothelial precursor cells (MPC)
Externí odkaz:
https://doaj.org/article/b350fb321a7d40b385a5f750f76e7298
Autor:
Licun Wu, Walter Blum, Chang-Qi Zhu, Zhihong Yun, Laszlo Pecze, Mikihiro Kohno, Mei-Lin Chan, Yidan Zhao, Emanuela Felley-Bosco, Beat Schwaller, Marc de Perrot
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background Cancer cell repopulation during chemotherapy or radiotherapy is a major factor limiting the efficacy of treatment. Cancer stem cells (CSC) may play critical roles during this process. We aim to demonstrate the role of mesothelioma
Externí odkaz:
https://doaj.org/article/0356c2c246ab4de6bc26892cd2162632