Výsledky vyhledávání - "Licia Pacifici"

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Autor: S. Pace, A Longo, Giuseppina Morini, P Lo Giudice, Paolo Carminati, Licia Pacifici, Daniela Grandi, C. Pisano, Gabriella Coruzzi, G Coppelli, Loredana Vesci

Publikováno v: Digestive Diseases and Sciences. 44:713-724

The effect of the nonsteroidal antiinflammatorydrug (NSAID) amtolmetin guacyl (AMG) on the gastricmucosa was studied in the rat by means of histologicaland functional techniques. AMG administered at 50-300 mg/kg intragastrically was virtuallydevoid o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19357353b2f02c15057ae5d4f3f6d881
https://doi.org/10.1023/a:1026653623516

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A Markovian formalization of heart rate dynamics evinces a quantum-like hypothesis

Autor: Charles L. Webber, Alessandro Giuliani, Pietro Lo Giudice, Michail Zak, Gianni Quatrini, Licia Pacifici, Anna Maria Mancini, Joseph P. Zbilut

Publikováno v: Scopus-Elsevier

Most investigations into heart rate dynamics have emphasized continuous functions, whereas the heart beat itself is a discrete event. We present experimental evidence that by considering this quality, the dynamics may be appreciated as a result of si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381d85c0000e237eb049f41b4c5a282b
https://doi.org/10.1007/bf00204206

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Acetyl-l-carnitine treatment increases choline acetyltransferase activity and NGF levels in the CNS of adult rats following total fimbria-fornix transection

Autor: Paola Piovesan, Giulio Taglialatela, Luciano Angelucci, M.T. Ramacci, Licia Pacifici

Publikováno v: Brain Research. 633:77-82

Transection of the fimbria-fornix in adult rats is a useful model for producing impairments of cholinergic activity in the hippocampus (HIPP) and atrophy of the medial septum cholinergic perikarya, similar to those observed during senescence, that ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643a6854b89d1d18d6443f5581377d69
https://doi.org/10.1016/0006-8993(94)91524-5

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Ameliorating effects of the immunomodulator 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole in an experimental model of colitis in the rat

Autor: Paolo Carminati, Vincenzo Sorrentino, Roberto Taurelli, Maria Antonietta Stasi, Margherita Aglianò, Paola Lorenzoni, Angela Ursillo, Elisabetta Weber, Licia Pacifici, Vito Ruggiero

Publikováno v: European journal of pharmacology. 494(2-3)

The therapeutic efficacy of the immunomodulator 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole (ST1959) in colonic inflammation was assessed in rats. One hour following colonic instillation of ethanolic 2,4,6-trinitrobenzene sulphonic acid (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6be0af37e9016371cfd9571ce9a7b38
https://pubmed.ncbi.nlm.nih.gov/15212983

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Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents

Publikováno v: ResearcherID

Recently we reported the pharmacological characterization of the 9,10-dihydropyrrolo[1,3]benzothiazepine derivative (S)-(+)-8 as a novel atypical antipsychotic agent. This compound had an optimum pK(i) 5-HT(2A)/D(2) ratio of 1.21 (pK(i) 5-HT(2A) = 8.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cd238cf464644cefa3306780bf2fd3
http://hdl.handle.net/11588/200968

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Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine

Autor: Claudio, Pisano, Graziella, Pratesi, Diletta, Laccabue, Franco, Zunino, Pietro, Lo Giudice, Augusta, Bellucci, Licia, Pacifici, Barbara, Camerini, Loredana, Vesci, Massimo, Castorina, Sandra, Cicuzza, Giovanni, Tredici, Paola, Marmiroli, Gabriella, Nicolini, Stefania, Galbiati, Menotti, Calvani, Paolo, Carminati, Guido, Cavaletti

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 9(15)

Antineoplastic drugs belonging to platinum or taxane families are severely neurotoxic, inducing the onset of disabling peripheral neuropathies with different clinical signs. Acetyl-L-carnitine (ALC) is a natural occurring compound with a neuroprotect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ac808fb35a35b28419bc709f540cabd
https://pubmed.ncbi.nlm.nih.gov/14654561

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EEG power spectra changes and forebrain ischemia in rats

Autor: Maria Antonietta Stasi, Roberto Taurelli, Maria Vittoria Ambrosini, Michela Tantucci, Paolo Nardò, Licia Pacifici, Paolo Carminati, Giuseppina Mariucci

Background:Several animal models of cerebral ischemia have been developed to investigate both pathophysiology and pharmacological treatment. The aim of this study was to verify the prognostic value of EEG power spectra analysis in a two-vessel plus h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad599b860f9a2e720b35b349bb9e2b5
http://hdl.handle.net/11391/158426

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Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies

The prototypical dopamine and serotonin antagonist (+/-)-7-chloro-9-(4-methylpiperazin-1-yl)-9,10-dihydropyrrolo[2,1-b][1,3]benzothiazepine (5) was resolved into its R and S enantiomers via crystallization of the diastereomeric tartaric acid salts. B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7242cc026a21da1ffb1bf9100ab8aa3
http://hdl.handle.net/11365/19281

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Autonomic nervous system activity imbalance in cardiomyopathic hamster

Autor: Jean Pierre Gagnol, Pietro Lo Giudice, Giovanna Buffone, Giuseppina Magni, Licia Pacifici, Augusta Bellucci, Teresa Quagliata, Antonia Careddu, Paolo Carminati

Publikováno v: Journal of cardiovascular pharmacology. 36(3)

There is strong evidence that autonomic imbalance plays an important role in progression of heart failure. Analysis of heart rate variability (HRV) has achieved substantial acceptance as a noninvasive method for the assessment of autonomic tone. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e8a078262b48b11c3b4596558a6d66
https://pubmed.ncbi.nlm.nih.gov/10975595

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Acetyl-L-carnitine restores choline acetyltransferase activity in the hippocampus of rats with partial unilateral fimbria-fornix transection

Autor: Giulio Taglialatela, Luciano Angelucci, Gianni Quatrini, Licia Pacifici, Paola Piovesan

Publikováno v: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 13(1)

Transection of the fimbria-fornix bundle in adult rats results in degeneration of the septo-hippocampal cholinergic pathway, reminiscent of that occurring in aging as well as Alzheimer disease. We report here a study of the effect of a treatment with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ede20c8bd8d8534ed97c26d08f9621f
https://pubmed.ncbi.nlm.nih.gov/7793306

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