Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Lichun Shen"'
Autor:
Min Shao, Yongxiurong Liu, Weiguo Cao, Wei Zhou, Lichun Shen, Xiao-Jun Tang, Lan Yao, Hongmei Deng, Hui Zhang, Jie Chen
Publikováno v:
Synthesis. 54:429-438
A novel synthesis of fused perfluoroalkylated 2,3-dihydroisoxazoles is achieved via oxa-Michael-aldol annulation between perfluoroalk-2-ynoates and N-hydroxyimides. This method provides a convenient route for the synthesis of pyrrolidin-2-one-fused p
Autor:
Min Shao, Qi Huang, Wei Zhou, Lichun Shen, Weiguo Cao, Hui Zhang, Jing Han, Jie Chen, Weimin He, Hongmei Deng
Publikováno v:
Synlett. 32:1197-1200
A protocol for the synthesis of 4-perfluoroalkylated 2H-pyran-2-ones bearing indole skeleton is reported. This efficient synthesis involves a Et3N-promoted Michael addition/enolization/cyclization cascade process at 40 °C in air, using 3-(1-methyl-1
Publikováno v:
Organic Process Research & Development. 18:1142-1144
A practical, highly selective O-ethylation method of N-Boc amino alcohols under phase-transfer catalyzed conditions is described. The O-ethylation was accomplished in heptanes or toluene using 50% aqueous sodium hydroxide as the base in the presence
Publikováno v:
Tetrahedron Letters. 49:6404-6409
A stereospecific Saucy–Marbet rearrangement of alkynyl halides is described here. These rearrangements provide an entry to highly enantiomerically enriched allenyl bromides and chlorides through excellent chirality transfer and the preservation of
Autor:
Lichun Shen, Richard P. Hsung
Publikováno v:
Tetrahedron Letters. 44:9353-9358
Pauson–Khand cycloadditions using chiral ynamides are achieved in modest to good yields with excellent regioselectivity and modest stereoselectivity. An unusual endo addition is found when using norbornadiene and substituted ynamides, leading to cy
Autor:
Craig A. Zificsak, Lichun Shen, Michael O. Frederick, Jason A. Mulder, Kimberly C. M. Kurtz, Richard P. Hsung, Heather A. Coverdale
Publikováno v:
Organic Letters. 5:1547-1550
A highly stereoselective preparation of novel chiral (E)-alpha-haloenamides under mild conditions utilizing magnesium halide salts is described. This unexpected mild and efficient hydrohalogenation reaction highlights another synthetic utility of yna
Publikováno v:
Tetrahedron Letters. 43:4449-4453
The first study of stereoselective epoxidations of chiral enamides is described here. Its potential in the synthesis of chiral α-keto aminals as a viable approach to nitrogen stabilized oxyallyl cations in stereoselective [4+3] cycloadditions is als
Publikováno v:
Organic Process Research & Development. 12:778-780
A practical method for the N-detosylation of indoles and related heterocycles with KOH in THF and water in the presence of a phase transfer catalyst is described. Using a nonalcoholic solvent, this...
Publikováno v:
ChemInform. 33
The first study of stereoselective epoxidations of chiral enamides is described here. Its potential in the synthesis of chiral α-keto aminals as a viable approach to nitrogen stabilized oxyallyl cations in stereoselective [4+3] cycloadditions is als
Publikováno v:
ChemInform. 40
A stereospecific Saucy–Marbet rearrangement of alkynyl halides is described here. These rearrangements provide an entry to highly enantiomerically enriched allenyl bromides and chlorides through excellent chirality transfer and the preservation of