Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lichong Yan"'
Autor:
Ze Rui Wu, Lichong Yan, Yan Ting Liu, Lei Cao, Yu Hang Guo, Yong Zhang, Hong Yao, Lin Cai, Han Bing Shang, Wei Wei Rui, Gang Yang, Xiao Biao Zhang, Hao Tang, Yu Wang, Jin Yan Huang, Yong Xu Wei, Wei Guo Zhao, Bing Su, Zhe Bao Wu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
LncRNA H19 has been shown to be aberrantly expressed in different cancers. Here, the authors show that H19 lncRNA is downregulated in pituitary adenomas and H19 is able to impede pituitary tumorigenesis via disruption of 4E-BPB1 and Raptor interactio
Externí odkaz:
https://doaj.org/article/06d60b35e5174563a00cf014ab758ffe
Autor:
Weiwei Guo, Lichong Yan, Ling Yang, Xiaoyu Liu, Qiukai E, Peiye Gao, Xiaofei Ye, Wen Liu, Ji Zuo
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85766 (2014)
Heat shock protein 90 (HSP90) inhibitors are potential drugs for cancer therapy. The inhibition of HSP90 on cancer cell growth largely through degrading client proteins, like Akt and p53, therefore, triggering cancer cell apoptosis. Here, we show tha
Externí odkaz:
https://doaj.org/article/e7a4610552ec45199b2e470f150c8082
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/28/2024, Vol. 121 Issue 22, p1-11, 14p
Autor:
Lichong Yan, Y. Grace Chen
Publikováno v:
Trends Biochem Sci
Circular RNAs (circRNAs) are a diverse class of RNAs with varying sizes, cellular abundance, and biological functions. Investigations from the past decade have revealed that circRNAs are ubiquitously found in eukaryotes and have defined the different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de04e7353186a155eafe827877c8d542
https://doi.org/10.1016/j.tibs.2020.08.006
https://doi.org/10.1016/j.tibs.2020.08.006
Autor:
Youqiong Ye, Lichong Yan, Qiang Zou, Richard A. Flavell, Jing Zhou, Jiajia Hu, Hua-Bing Li, Xingli Zhang, Hao Xu, Huifang Chen, Zhengting Wang, Chenbo Ding, Rihao Qu, Zhibin Yu
Publikováno v:
Science Advances. 7
N6-methyladenosine (m6A) modification is dynamically regulated by "writer" and "eraser" enzymes. m6A "writers" have been shown to ensure the homeostasis of CD4+ T cells, but the "erasers" functioning in T cells is poorly understood. Here, we reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c1e7576f731e0300f66465925bc6c4
https://doi.org/10.1126/sciadv.abg0470
https://doi.org/10.1126/sciadv.abg0470
Autor:
Xinxing Ouyang, Omotooke Arojo, Hongzhi Liu, Guojun Qu, Fubin Li, Wenqian Zhang, Yuheng Han, Yuhong Fu, Bing Su, Huihui Zhang, Qijun Wang, Chuanxin Huang, Jingsi Jin, Lu Lu, Xiaocao Xu, Adam S. Lazorchak, Lichong Yan, Chuan Ruan, Shibo Jiang, Zhengfeng Yang, Man Li, Xiaobo Liu, Dou Liu
Publikováno v:
Cell Mol Immunol
Proper control of B cell growth and metabolism is crucial for B-cell-mediated immunity, but the underlying molecular mechanisms remain incompletely understood. In this study, Sin1, a key component of mTOR complex 2 (mTORC2), specifically regulates B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e04e11dcfc825395e110618ea293525
https://doi.org/10.1038/s41423-018-0185-x
https://doi.org/10.1038/s41423-018-0185-x
Autor:
Junfeng Zhang, Xinxing Ouyang, Lichong Yan, Bing Su, Song Xue, Yanyan Xu, Zhenlei Hu, Jianmin Gu, Xuemei Fan, Guo-Qiang Chen, Lin Zhang, Junling Liu, Mingliang Zhang
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:2793-2805
Objective— Microthrombosis as a serious consequence of myocardial infarction, impairs the microvascular environment and increases the occurrences of heart failure, arrhythmia, and death. Sin1 (stress-activated protein kinase-interacting protein) as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7f24cd8621c2609f93ed7a7dad9a50
https://doi.org/10.1161/atvbaha.118.311822
https://doi.org/10.1161/atvbaha.118.311822
Autor:
Jing, Zhou, Xingli, Zhang, Jiajia, Hu, Rihao, Qu, Zhibin, Yu, Hao, Xu, Huifang, Chen, Lichong, Yan, Chenbo, Ding, Qiang, Zou, Youqiong, Ye, Zhengting, Wang, Richard A, Flavell, Hua-Bing, Li
Publikováno v:
Science Advances
ALKBH5 maintains CD4+ T cell pathogenicity during autoimmune disease via regulating IFN-γ and CXCL2.
N6-methyladenosine (m6A) modification is dynamically regulated by “writer” and “eraser” enzymes. m6A “writers” have been shown to e
N6-methyladenosine (m6A) modification is dynamically regulated by “writer” and “eraser” enzymes. m6A “writers” have been shown to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e45f4dddc2a5ae5680996dfaf79668bf
https://pubmed.ncbi.nlm.nih.gov/34134995
https://pubmed.ncbi.nlm.nih.gov/34134995
Autor:
Lichong Yan, Y. Grace Chen
Publikováno v:
Cell. 183(1)
Circular RNAs (circRNAs) have emerged as key regulators of a wide variety of biological processes, but the roles of mitochondrial circRNAs are largely unknown. In this issue of Cell, Zhao et al. (2020) reveal that mitochondrial DNA-encoded circRNAs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cce20a4f489f7169f7b20ffafaa9cf3
https://pubmed.ncbi.nlm.nih.gov/32931733
https://pubmed.ncbi.nlm.nih.gov/32931733
Autor:
Siqi Wu, Xiaolu Zhou, Yuanlong Sun, Wensheng Pan, Yongxiu Zhang, Jianping Jiang, Hang Xiao, Yongchao Hu, Xiaofang Zheng, Lizhong Xie, Yuhuan Zhong, Yu Zhang, Ruizhang Su, Changhua Zhang, Yi Zhang, Shuisheng Wu, Zhenghua Jiang, Xugong Li, Wen Xu, Huafen Zhu, Zhang Wen, Wenxia Li, Yemei Bu, Chao Dong, Wangyue Wang, Chen Yang, Hu Yiqun, Yulong He, Haineng Xu, Limin Ding, Zhaofang Han, Lichong Yan, Wenjuan Qin, Hong Chen, Sijun Meng, Hesong Qiu, Wen Zhang, Yueping Zheng
Background: Early detection and treatment under endoscopy have effectively decreased the mortality of colorectal cancer (CRC). But it is difficult to detect early CRC under white light endoscopy (WLE). Artificial intelligence (A.I.) assisted diagnose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945a23c0893a4a739e0bfb80814b7a72
