Výsledky vyhledávání - "Libuse Oupicka"

Abstract 156: Dynamic live-cell visualization and quantification of Akt activity using a genetically-encoded, fluorescent kinase translocation reporter

Autor: John N. Rauch, Susan K. Foltin, Libuse Oupicka, Matthew Dilsaver, Grigory S. Filonov, Gillian Lovell, Jasmine Trigg, Cicely L. Schramm

Publikováno v: Cancer Research. 82:156-156

Dysregulation of signal transduction pathways is associated with cancer initiation, progression, and recurrence. The PI3K/Akt signaling pathway has been extensively investigated as a therapeutic target due to its mechanistic association with several

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f538e8ef6a5b2a6ad2fe105ad4b2afb
https://doi.org/10.1158/1538-7445.am2022-156

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Abstract 1834: Real-time visualization and quantification of flexible, multi-parameter indicators of cancer cell heath and metabolism using live-cell analysis

Autor: Yong X. Chen, Grigory S. Filonov, Ilya Kovalenko, Libuse Oupicka, Laura A. Skerlos, Hinnah Campwala, Nicola Bevan, Sandra Perez-Garrido, Gillian Lovell, Timothy Dale, Cicely L. Schramm, Daniel M. Appledorn, John N. Rauch, Susan K. Foltin

Publikováno v: Cancer Research. 80:1834-1834

The ability to perform concurrent, dynamic measurements of multiple parameters of tumor cell health can provide valuable mechanistic insight. For example, a single compound may exhibit cytotoxic and/or cytostatic properties, depending on the tumor ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07c411a5c2ca67e3421c76984a0d5930
https://doi.org/10.1158/1538-7445.am2020-1834

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