Zobrazeno 1 - 10
of 1 499
pro vyhledávání: '"Library Screening"'
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Corynebacterium glutamicum is an attractive host for secretory production of recombinant proteins, including high-value industrial enzymes and therapeutic proteins. The choice of an appropriate signaling peptide is crucial for eff
Externí odkaz:
https://doaj.org/article/08a67ce3ffae4701a9cd4fddae396081
Autor:
Sang Ryeol Park, Seungmin Son
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
The environmental conditions play a crucial role in determining crop yield, which is essential for ensuring food and nutritional security. However, rapid climate change is exacerbating global environmental stress, leading to severe biotic pressures o
Externí odkaz:
https://doaj.org/article/e0427d1709af4a34b7400f05315b3045
Publikováno v:
Artificial Intelligence Chemistry, Vol 2, Iss 1, Pp 100044- (2024)
Targeting riboswitches, regulatory elements responsible for the expression of essential genes, is taking central stage in the new era of antibacterial medications discovery due to the emergence of antibiotic resistance. The S-Adenosyl methionine-I (S
Externí odkaz:
https://doaj.org/article/77ebac23e9d24e07a7d5d4eab51f09c4
Autor:
Dong-hee Lee, Hyejin Ahn, Hye-In Sim, Eunji Choi, Seunghyun Choi, Yunju Jo, Bohwan Yun, Hyun Kyu Song, Soo Jin Oh, Kaori Denda-Nagai, Chan-Sik Park, Tatsuro Irimura, Yoon Park, Hyung-seung Jin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Immunotherapy has significantly advanced cancer treatments, but many patients do not respond to it, partly due to immunosuppressive mechanisms used by tumor cells. These cells employ immunosuppressive ligands to evade detection an
Externí odkaz:
https://doaj.org/article/5a2155d0c9c541b7b2a52446c3747bb0
Autor:
Kazuma Ohdate, Minori Sakata, Kaisei Maeda, Yutaka Sakamaki, Kaori Nimura-Matsune, Ryudo Ohbayashi, Wolfgang R. Hess, Satoru Watanabe
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Numerous cyanobacteria capable of oxygenic photosynthesis possess multiple large plasmids exceeding 100 kbp in size. These plasmids are believed to have distinct replication and distribution mechanisms, as they coexist within cells without causing in
Externí odkaz:
https://doaj.org/article/8a7ead2e51ea458486b65d25e7dcc396
Autor:
Jonathan Walgraeve, Borja Ferrero-Bordera, Sandra Maaß, Dörte Becher, Ruth Schwerdtfeger, Jan Maarten van Dijl, Michael Seefried
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules. In recent years, advancements have been made to engineer the bacteriu
Externí odkaz:
https://doaj.org/article/77eafae8802043549af3119d1b73e946
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT New antibacterial agents and agent combinations are urgently needed to combat antimicrobial resistance. A multidimensional chemical library screening strategy was used to identify compounds in the National Cancer Institute (NCI) diversity se
Externí odkaz:
https://doaj.org/article/249011a780e74a68a80a5dd2bbef40cc
Autor:
Danqi Zeng, Can Si, Jaime A. Teixeira da Silva, Hongyu Shi, Jing Chen, Lei Huang, Juan Duan, Chunmei He
Publikováno v:
BMC Plant Biology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Gibberellins (GAs) are widely involved in plant growth and development. DELLA proteins are key regulators of plant development and a negative regulatory factor of GA. Dendrobium officinale is a valuable traditional Chinese medicin
Externí odkaz:
https://doaj.org/article/2a0ee2be366441408423d54cae94fc22
CRISPR library screening to develop HEK293-derived cell lines with improved lentiviral vector titers
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
Lentiviral (LV) vectors have emerged as powerful tools for treating genetic and acquired human diseases. As clinical studies and commercial demands have progressed, there has been a growing need for large amounts of purified LV vectors. To help meet
Externí odkaz:
https://doaj.org/article/37bb34bf934f49fa9655358b512911da
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