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Publikováno v:
The Journal of Clinical Pharmacology. 40:354-359
Ketoprofen is a nonsteroidal anti-inflammatory drug with analgesic, anti-inflammatory, and antipyretic properties. Its pharmacokinetics has not been determined in small children. The objective here was to determine the pharmacokinetics of ketoprofen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fca9e4f5a373d28b4dca7995a8435c
https://doi.org/10.1177/00912700022009053
https://doi.org/10.1177/00912700022009053
Publikováno v:
Rheumatology. 38:564-567
Objective The primary objective of this study was to assess the kinetics of ketoprofen in synovial fluid and intra-articular tissues in relation to plasma. The secondary objective was to study whether intra-articular tissues act as reservoirs. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12a0b2ce1400a72a0032c1cd36bc1f6
https://doi.org/10.1093/rheumatology/38.6.564
https://doi.org/10.1093/rheumatology/38.6.564
Autor:
E. Groen, G. Montay, C. Guimart, S. Kirkesseli, J. Wemer, Jan H. G. Jonkman, J.-Y. Gautier, A. Le Liboux, P. A. M. Peeters, J.-P. Cachia
Publikováno v:
The Journal of Clinical Pharmacology. 39:480-486
The pharmacokinetics and tolerability of the novel antiexcitatory agent, riluzole, were compared in 18 healthy elderly and 18 healthy gender- and weight-matched young volunteers. All participants received riluzole 50 mg twice daily (the recommended d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ccf5758a24d6c189cef81e15afe144d
https://doi.org/10.1177/009127009903900507
https://doi.org/10.1177/009127009903900507
Autor:
S Le Liboux, Jean-Louis Peyraud
Publikováno v:
Animal Feed Science and Technology
Animal Feed Science and Technology, Elsevier Masson, 1999, 76, pp.297-319
Animal Feed Science and Technology, Elsevier Masson, 1999, 76, pp.297-319
This trial aimed at studying the effects and possible interactions between forage particle size and feeding frequency on the site and extent of digestion and ruminal fermentations throughout the day in dairy cows fed mixed diets. Two forage particle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ab98f89fa8392a669cb081d7c9bd20
https://doi.org/10.1016/s0377-8401(98)00220-x
https://doi.org/10.1016/s0377-8401(98)00220-x
Autor:
Nicole Vivier, G. Montay, Larry K. Powe, J. C. Delumeau, Rene Bruno, Gerald R. Rhodes, Aim éLe Liboux
Publikováno v:
Clinical Pharmacology & Therapeutics. 62:518-526
Objectives To characterize the population pharmacokinetic of riluzole in patients with amyotrophic lateral sclerosis (ALS). Methods One hundred patients with ALS who were participating in a multicenter phase III dose-ranging trial of riluzole were sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5229af6ccd23328342ae06b91c8888
https://doi.org/10.1016/s0009-9236(97)90047-3
https://doi.org/10.1016/s0009-9236(97)90047-3
Autor:
G. Montay, Patricia Lefebvre, Stéphane Kirkesseli, Michel Aubeneau, Yvonne Le Roux, Philippe Truffinet, Aimé Le Liboux
Publikováno v:
The Journal of Clinical Pharmacology. 37:820-827
Riluzole is a novel neuroprotective agent that has been developed for the treatment of amyotrophic lateral sclerosis. A series of studies was undertaken to establish its pharmacokinetics on single- and multiple-dose administration in young white male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e48b22f4e42620cd21d00fa3a00f0d
https://doi.org/10.1002/j.1552-4604.1997.tb05630.x
https://doi.org/10.1002/j.1552-4604.1997.tb05630.x
Publikováno v:
Journal Français d'Ophtalmologie. 27:401-403
Les auteurs presentent un cas de keratite fongique survenue chez une jeune femme porteuse depuis deux ans de lentilles corneennes jetables journalieres. Ce cas, qui a evolue favorablement sous therapeutique specifique et pour lequel aucun facteur de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc683f8e386f1a1fb94d9fd7b85a2ba3
https://doi.org/10.1016/s0181-5512(04)96149-9
https://doi.org/10.1016/s0181-5512(04)96149-9
Publikováno v:
European Journal of Clinical Pharmacology. 47:361-366
The indirect effect of diet on the single-and multiple-dose pharmacokinetics of sustained-release ketoprofen was studied in 16 healthy male volunteers. In an open, cross-over design, 200 mg ketoprofen was administered as a gastric-juice-resistant, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e678d6008a69a6aff88aeee1599132
https://doi.org/10.1007/bf00191169
https://doi.org/10.1007/bf00191169
Kinetics of spiramycin/metronidazole (RodogylR) in human gingival crevicular fluid, saliva and blood
Publikováno v:
Journal of Clinical Periodontology. 21:595-600
The peripheral distribution of spiramycin and metronidazole, which are combined in the proprietary drug "Rodogyl", has been studied in gingival fluid, saliva and blood after a single administration to 12 healthy volunteers and after repeated administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283c09a6f4fa54cda33cd0508cff5d8f
https://doi.org/10.1111/j.1600-051x.1994.tb00749.x
https://doi.org/10.1111/j.1600-051x.1994.tb00749.x