Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Libor Vítek"'
Autor:
Helena Gbelcová, Silvie Rimpelová, Adriana Jariabková, Patrik Macášek, Petra Priščáková, Tomáš Ruml, Jana Šáchová, Jan Kubovčiak, Michal Kolář, Libor Vítek
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Statins, the drugs used for the treatment of hypercholesterolemia, have come into the spotlight not only as chemoadjuvants, but also as potential stem cell modulators in the context of regenerative therapy. In our study, we compared the in v
Externí odkaz:
https://doaj.org/article/a2b1444916ff47fd88579fb1c2a86160
Publikováno v:
Sports Medicine - Open, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Although regular physical activity improves immune competency and reduces the prevalence of inflammatory diseases, strenuous training in elite athletes is associated with an increased susceptibility to infectious complications. Th
Externí odkaz:
https://doaj.org/article/5ee5965eaeb44b779b6856213fb4f0cd
Autor:
Patrik Šimják, Tomáš Petr, Barbora Kaslová, Tomáš Fejfar, Petr Hůlek, Antonín Pařízek, Libor Vítek
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-5 (2022)
Abstract In the literature on the safety of ursodeoxycholic acid (UDCA) during breastfeeding, insufficient data has been reported to date. Thus, the aim of our study was to analyze bile acid (BA) concentrations in breast milk in a cohort of patients,
Externí odkaz:
https://doaj.org/article/4bbf7ee925e74a8da1b0413678664482
Autor:
Václav Šmíd, Karel Dvořák, Kamila Stehnová, Hynek Strnad, Josep Rubert, Jan Stříteský, Barbora Staňková, Milena Stránská, Jana Hajšlová, Radan Brůha, Libor Vítek
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17226 (2023)
The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is associated with abnormalities of liver lipid metabolism. On the contrary, a diet enriched with n-3 polyunsaturated fatty acids (n-3-PUFAs) has been reported to ameliorate the progressio
Externí odkaz:
https://doaj.org/article/8dc7c626a1274dd2ac170c0229c75454
Autor:
Václav Šmíd, Karel Dvořák, Petr Šedivý, Vít Kosek, Martin Leníček, Monika Dezortová, Jana Hajšlová, Milan Hájek, Libor Vítek, Kamila Bechyňská, Radan Brůha
Publikováno v:
Hepatology Communications, Vol 6, Iss 6, Pp 1336-1349 (2022)
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. n‐3 polyunsaturated fatty acids (n‐3‐PUFAs) have been reported to ameliorate the progression of NAFLD in experimental studies; however, clinical trials have yiel
Externí odkaz:
https://doaj.org/article/ac9851f6a8084a2786db1dc1a9a79346
Publikováno v:
Frontiers in Sports and Active Living, Vol 4 (2023)
Exercise performance is dependent on many factors, such as muscular strength and endurance, cardiovascular capacity, liver health, and metabolic flexibility. Recent studies show that plasma levels of bilirubin, which has classically been viewed as a
Externí odkaz:
https://doaj.org/article/3835ac39877543ad929295403fae7b91
Autor:
Martin Leníček, Václav Šmíd, Petr Pajer, Anna Nazarova, Karel Dvořák, Iva Subhanová, Radan Brůha, Libor Vítek
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract The patatin-like phospholipase domain containing 3 (PNPLA3) gene (viz. its I148M variant) is one of the key players in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). We have identified a novel insertion/deletion variant of 111
Externí odkaz:
https://doaj.org/article/5581a4fd50f34deaa352f9233e04797f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10614 (2023)
Bilirubin has potent biological beneficial effects, protecting against atherosclerosis, obesity, and metabolic syndrome. The aim of this study was to assess serum bilirubin concentrations and (TA)n and (GT)n microsatellite variations in the promoter
Externí odkaz:
https://doaj.org/article/1f66eec237b84abc9c3fec0b383d600d
Autor:
Adam Čepa, Veronika Dejmková, Ladislav Lešetický, Ivan Jelínek, Stanislav Smrček, Martin Štícha, Jana Jašprová, Marie Urbanová, Iryna Goncharova, Martin Dračínský, Eliška Procházková, Donald J. Ostrow, Libor Vítek
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Unconjugated bilirubin (UCB) is the end-product of heme catabolism in the intravascular compartment. Although beneficial for human health when mildly elevated in the body, when present at greater than a critical threshold concentration, UCB
Externí odkaz:
https://doaj.org/article/76e84440156a41a0b3afe937582ade16
Autor:
Lori W. E. van der Schoor, Henkjan J. Verkade, Anna Bertolini, Sanne de Wit, Elvira Mennillo, Eva Rettenmeier, André A. Weber, Rick Havinga, Petra Valášková, Jana Jašprová, Dicky Struik, Vincent W. Bloks, Shujuan Chen, Andrea B. Schreuder, Libor Vítek, Robert H. Tukey, Johan W. Jonker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Neonatal hyperbilirubinemia or jaundice is associated with kernicterus, resulting in permanent neurological damage or even death. Conventional phototherapy does not prevent hyperbilirubinemia or eliminate the need for exchange transfusion. H
Externí odkaz:
https://doaj.org/article/59f5708413df43f992dcb9093f632208