Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Libor Krasny"'
Autor:
Tomáš Kovaľ, Nabajyoti Borah, Petra Sudzinová, Barbora Brezovská, Hana Šanderová, Viola Vaňková Hausnerová, Alena Křenková, Martin Hubálek, Mária Trundová, Kristýna Adámková, Jarmila Dušková, Marek Schwarz, Jana Wiedermannová, Jan Dohnálek, Libor Krásný, Tomáš Kouba
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Mycobacterial HelD is a transcription factor that recycles stalled RNAP by dissociating it from nucleic acids and, if present, from the antibiotic rifampicin. The rescued RNAP, however, must disengage from HelD to participate in subsequent r
Externí odkaz:
https://doaj.org/article/b4ae507a61d547bd9ec5f46e0019e458
Autor:
Simon Woelfel, Anja Poehlein, Katrin Gunka, Rolf Daniel, Debora Kalalova, Martin Benda, Libor Krasny, Hana Šanderová, Joerg Stuelke, Stefan Klumpp
RNA turnover is essential in all domains of life. The endonuclease RNase Y (rny) is one of the key components involved in RNA metabolism of the model organism Bacillus subtilis. Essentiality of RNase Y has been a matter of discussion, since deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6b7215e1c1962bf1b2711fa302abd1f
https://doi.org/10.1101/2020.05.20.106237
https://doi.org/10.1101/2020.05.20.106237
Autor:
Jiří Pospíšil, Marek Schwarz, Alice Ziková, Dragana Vítovská, Miluše Hradilová, Michal Kolář, Alena Křenková, Martin Hubálek, Libor Krásný, Jiří Vohradský
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract σ factors are considered as positive regulators of gene expression. Here we reveal the opposite, inhibitory role of these proteins. We used a combination of molecular biology methods and computational modeling to analyze the regulatory acti
Externí odkaz:
https://doaj.org/article/f78d9ae48e1f449baab58082cc7107ca
Publikováno v:
Journal of Bacteriology. 189:4809-4814
The ybxF gene is a member of the streptomycin operon in a wide range of gram-positive bacteria. In Bacillus subtilis , it codes for a small basic protein (82 amino acids, pI 9.51) of unknown function. We demonstrate that, in B. subtilis , YbxF locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6802a16eca3a9e85af9785d765a2dbd2
https://doi.org/10.1128/jb.01786-06
https://doi.org/10.1128/jb.01786-06
Autor:
Jiri Jonak, Libor Krasny
Publikováno v:
FEMS Microbiology Letters. 183:143-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5f3b83bd90b8040cd769b4b1214cf3
https://doi.org/10.1016/s0378-1097(99)00657-6
https://doi.org/10.1016/s0378-1097(99)00657-6
Autor:
Libor Krasny, Xiao Yang, Peter J. Lewis, Jana Wiedermannová, Andrew N. Keller, Olivier Delumeau
Publikováno v:
Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2014, 196 (20), pp.3622-3632. ⟨10.1128/JB.02020-14⟩
Journal of Bacteriology, American Society for Microbiology, 2014, 196 (20), pp.3622-3632. ⟨10.1128/JB.02020-14⟩
RNA polymerase in bacteria is a multisubunit protein complex that is essential for gene expression. We have identified a new subunit of RNA polymerase present in the high-A+T Firmicutes phylum of Gram-positive bacteria and have named it epsilon. Prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008ab9acd3f3a1aa735da0d6dce6026e
https://hal.archives-ouvertes.fr/hal-01204433
https://hal.archives-ouvertes.fr/hal-01204433
Autor:
Duy Dinh Do Pham, Věra Jenčová, Miriam Kaňuchová, Jan Bayram, Ivana Grossová, Hubert Šuca, Lukáš Urban, Kristýna Havlíčková, Vít Novotný, Petr Mikeš, Viktor Mojr, Nikifor Asatiani, Eva Kuželová Košťáková, Martina Maixnerová, Alena Vlková, Dragana Vítovská, Hana Šanderová, Alexandr Nemec, Libor Krásný, Robert Zajíček, David Lukáš, Dominik Rejman, Peter Gál
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Active wound dressings are attracting extensive attention in soft tissue repair and regeneration, including bacteria-infected skin wound healing. As the wide use of antibiotics leads to drug resistance we present here a new concept of wound
Externí odkaz:
https://doaj.org/article/64cdaee56ed840f5a816a7b0b783e212
Publikováno v:
2010 3rd International Conference on Biomedical Engineering and Informatics.
The impedance method was used to detect bacterial layer on the surface of micro-electrodes. The interdigital electrodes arrangement was simulated by FEM to determine the detection distance of the sensor. Then, the KB-12 sensor with spacing 15 µm was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aeb7d3d850d1c78fd0f871324f94f6a
https://doi.org/10.1109/bmei.2010.5639411
https://doi.org/10.1109/bmei.2010.5639411
Autor:
Viola Vaňková Hausnerová, Olga Marvalová, Michaela Šiková, Mahmoud Shoman, Jarmila Havelková, Milada Kambová, Martina Janoušková, Dilip Kumar, Petr Halada, Marek Schwarz, Libor Krásný, Jarmila Hnilicová, Josef Pánek
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Bacteria employ small non-coding RNAs (sRNAs) to regulate gene expression. Ms1 is an sRNA that binds to the RNA polymerase (RNAP) core and affects the intracellular level of this essential enzyme. Ms1 is structurally related to 6S RNA that binds to a
Externí odkaz:
https://doaj.org/article/73dc8bdd26974b789648cd55eeb57de6
Autor:
Tomáš Kouba, Tomáš Koval’, Petra Sudzinová, Jiří Pospíšil, Barbora Brezovská, Jarmila Hnilicová, Hana Šanderová, Martina Janoušková, Michaela Šiková, Petr Halada, Michal Sýkora, Ivan Barvík, Jiří Nováček, Mária Trundová, Jarmila Dušková, Tereza Skálová, URee Chon, Katsuhiko S. Murakami, Jan Dohnálek, Libor Krásný
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The bacterial helicase-like transcription factor HelD associates with the RNA polymerase (RNAP) and recycles stalled transcription complexes. Here, the authors present the cryo-EM structures of three Mycobacterium smegmatis HelD bound RNAP complexes
Externí odkaz:
https://doaj.org/article/d65a4f9aaa6b499b97c7834c0fbc8302