GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis.

Autor: Cocozza G; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy. Electronic address: germana.cocozza@uniroma1.it., Busdraghi LM; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Chece G; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Menini A; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Ceccanti M; Department of Human Neuroscience, Sapienza University, Rome, Italy., Libonati L; Department of Human Neuroscience, Sapienza University, Rome, Italy., Cambieri C; Department of Human Neuroscience, Sapienza University, Rome, Italy., Fiorentino F; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Rome, Italy., Rotili D; Department of Science, Roma Tre University, Rome, Italy., Scavizzi F; EMMA CNR, Monterotondo, Italy., Raspa M; EMMA CNR, Monterotondo, Italy., Aronica E; Amsterdam UMC, University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Meibergdreef 9, Amsterdam, the Netherlands., Inghilleri M; Department of Human Neuroscience, Sapienza University, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy., Garofalo S; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Limatola C; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy; IRCCS Neuromed, Pozzilli, Italy. Electronic address: cristina.limatola@uniroma1.it.

Publikováno v: Brain, behavior, and immunity [Brain Behav Immun] 2024 Dec 11; Vol. 124, pp. 280-293. Date of Electronic Publication: 2024 Dec 11.

Oxidative Stress in Transthyretin-Mediated Amyloidosis: An Exploratory Study.

Autor: Fiore M; CNR-Institute of Biochemistry and Cell Biology, Via Ercole Ramarini 32, 00015 Monterotondo, Italy., Cambieri C; Center for Rare Neuromuscular Diseases, Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy., Libonati L; Center for Rare Neuromuscular Diseases, Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy., Moret F; Center for Rare Neuromuscular Diseases, Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy., D'Andrea E; Center for Rare Neuromuscular Diseases, Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy., Di Certo MG; CNR-Institute of Biochemistry and Cell Biology, Via Ercole Ramarini 32, 00015 Monterotondo, Italy., Passananti C; CNR-Institute of Molecular Biology and Pathology, Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161 Rome, Italy., Gabanella F; CNR-Institute of Biochemistry and Cell Biology, Via Ercole Ramarini 32, 00015 Monterotondo, Italy., Corbi N; CNR-Institute of Molecular Biology and Pathology, Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 291, 00161 Rome, Italy., Garibaldi M; Department of Neuroscience, Mental Health, and Sensory Organs (NESMOS), Sant'Andrea Hospital, Sapienza University, 00189 Rome, Italy., Chimenti C; Department of Clinical, Internal, Anesthesiologist and Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy., Alfarano M; Department of Clinical, Internal, Anesthesiologist and Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy., Ferraguti G; Department of Experimental Medicine, Sapienza University of Rome, 00185 Roma, Italy., Francati S; Department of Experimental Medicine, Sapienza University of Rome, 00185 Roma, Italy., Inghilleri M; Center for Rare Neuromuscular Diseases, Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy.; IRCCS Neuromed, 86077 Pozzilli, Italy., Ceccanti M; Center for Rare Neuromuscular Diseases, Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185 Rome, Italy.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2024 Aug 18; Vol. 13 (8). Date of Electronic Publication: 2024 Aug 18.

Chronic inflammatory demyelinating polyneuropathy and HEV antibody status: A case-control study from Lazio, Italy.

Autor: Moret F; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy. Electronic address: federica.moret@uniroma1.it., Spada E; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases, Istituto Superiore di Sanità, Rome, Italy., Ceccanti M; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy., Libonati L; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy., D'Andrea E; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy., Villano U; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases, Istituto Superiore di Sanità, Rome, Italy., Madonna E; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases, Istituto Superiore di Sanità, Rome, Italy., Chionne P; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases, Istituto Superiore di Sanità, Rome, Italy., Carocci A; National Center for the Control and Evaluation of Medicines, Istituto Superiore di Sanità, Rome, Italy., Pisani G; National Center for the Control and Evaluation of Medicines, Istituto Superiore di Sanità, Rome, Italy., Fionda L; Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome, Rome, Italy., Antonini G; Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome, Rome, Italy., Petrucci A; Center for Neuromuscular and Neurological Rare Diseases, AO San Camillo Forlanini Hospital, C.ne Gianicolense 87, 00152 Rome, Italy., Bruni R; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases, Istituto Superiore di Sanità, Rome, Italy., Ciccaglione AR; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases, Istituto Superiore di Sanità, Rome, Italy., Taliani G; Department of Public Health and Infectious Diseases, Infectious and Tropical Medicine Unit, 'Policlinico Umberto I' Hospital, Sapienza University of Rome, Rome, Italy., Rivano Capparuccia M; Department of Public Health and Infectious Diseases, Infectious and Tropical Medicine Unit, 'Policlinico Umberto I' Hospital, Sapienza University of Rome, Rome, Italy., Nobile-Orazio E; Neuromuscular and Neuroimmunology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy; Department of Medical Biotechnology and Translational Medicine, Milan University, Milano, Italy., Inghilleri M; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy; IRCCS Neuromed Pozzilli, IS, Italy., Cambieri C; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy.

Publikováno v: Journal of the neurological sciences [J Neurol Sci] 2024 Apr 15; Vol. 459, pp. 122959. Date of Electronic Publication: 2024 Mar 12.

Retrospective observational study on the use of acetyl-L-carnitine in ALS.

Autor: Sassi S; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Bianchi E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Diamanti L; Neuro-Oncology Unit, IRCCS Mondino Foundation, Pavia, Italy., Tornabene D; Neuro-Oncology Unit, IRCCS Mondino Foundation, Pavia, Italy.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy., Sette E; UO di Neurologia Dipartimento Neuroscienze e Riabilitazione, Azienda Ospedaliera Universitaria di Ferrara, Ferrara, Italy., Medici D; Presidio Ospedaliero Fidenza AUSL Parma, Fidenza, Italy., Matà S; Dipartimento Neuromuscoloscheletrico e Degli Organi di Senso, Azienda Ospedaliero-Universitaria di Careggi, Florence, Italy., Leccese D; Dipartimento Neuromuscoloscheletrico e Degli Organi di Senso, Azienda Ospedaliero-Universitaria di Careggi, Florence, Italy., Sperti M; Dipartimento Neuromuscoloscheletrico e Degli Organi di Senso, Azienda Ospedaliero-Universitaria di Careggi, Florence, Italy., Martinelli I; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena, Italy.; Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy., Ghezzi A; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy., Mandrioli J; Department of Neurosciences, Azienda Ospedaliero Universitaria di Modena, Modena, Italy.; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.; Department of Biomedical, Metabolic and Neural Sciences, Centre for Neuroscience and Nanotechnology, University of Modena and Reggio Emilia, Modena, Italy., Iuzzolino VV; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy., Dubbioso R; Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy., Trojsi F; Dipartimento di Scienze Mediche e Chirurgiche Avanzate, Università degli Studi della Campania 'Luigi Vanvitelli', P.Zza Miraglia 2, Naples, Italy., Passaniti C; Dipartimento di Scienze Mediche e Chirurgiche Avanzate, Università degli Studi della Campania 'Luigi Vanvitelli', P.Zza Miraglia 2, Naples, Italy., D'Alvano G; Dipartimento di Scienze Mediche e Chirurgiche Avanzate, Università degli Studi della Campania 'Luigi Vanvitelli', P.Zza Miraglia 2, Naples, Italy., Filosto M; Department of Clinical and Experimental Sciences, NeMO-Brescia Clinical Center for Neuromuscular Diseases, University of Brescia, Brescia, Italy., Padovani A; Department of Clinical and Experimental Sciences, Unit of Neurology ASST Spedali Civili Di Brescia, University of Brescia, Brescia, Italy., Mazzini L; ALS Center Azienda Ospedaliero Universitaria 'Maggiore della Carità' e Università del Piemonte Orientale, Novara, Italy., De Marchi F; ALS Center Azienda Ospedaliero Universitaria 'Maggiore della Carità' e Università del Piemonte Orientale, Novara, Italy., Zinno L; Department of Medicine and Surgery, University of Parma, Parma, Italy., Nuredini A; Department of Medicine and Surgery, University of Parma, Parma, Italy., Bongioanni P; Dpt. Medical Specialties, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Dolciotti C; Dpt. Medical Specialties, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Canali E; U.O di Neurologia, Presidio Ospedaliero S.Maria Nuova Azienda USL, IRCCS di Reggio Emilia, Florence, Italy., Toschi G; U.O di Neurologia, Presidio Ospedaliero S.Maria Nuova Azienda USL, IRCCS di Reggio Emilia, Florence, Italy., Petrucci A; Center for Neuromuscular and Neurological Rare Diseases, San Camillo Forlanini Hospital, Rome, Italy., Perna A; Center for Neuromuscular and Neurological Rare Diseases, San Camillo Forlanini Hospital, Rome, Italy., Riso V; Center for Neuromuscular and Neurological Rare Diseases, San Camillo Forlanini Hospital, Rome, Italy., Inghilleri M; Dipartimento di Neuroscienze Umane, Università di Roma 'Sapienza' UOSD Malattie Neurodegenerative-Centro Malattie Rare Neuromuscolari, Policlinico Universitario Umberto I, Rome, Italy., Libonati L; Dipartimento di Neuroscienze Umane, Università di Roma 'Sapienza' UOSD Malattie Neurodegenerative-Centro Malattie Rare Neuromuscolari, Policlinico Universitario Umberto I, Rome, Italy. laura.libonati@uniroma1.it., Cambieri C; Dipartimento di Neuroscienze Umane, Università di Roma 'Sapienza' UOSD Malattie Neurodegenerative-Centro Malattie Rare Neuromuscolari, Policlinico Universitario Umberto I, Rome, Italy., Pupillo E; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Publikováno v: Journal of neurology [J Neurol] 2023 Nov; Vol. 270 (11), pp. 5344-5357. Date of Electronic Publication: 2023 Jun 28.

Does Patisiran Reduce Ocular Transthyretin Synthesis? A Pilot Study of Two Cases.

Autor: Cambieri C; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy., Marenco M; Department of Sense Organs, Sapienza University of Rome, Rome, Italy., Colasanti T; Department of Clinical Internal, Rheumatology Unit, Anesthetic and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy., Mancone C; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Corsi A; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Riminucci M; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Libonati L; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy., Moret F; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy., Chimenti C; Department of Clinical, Internal, Anesthesiologist and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.; Cellular and Molecular Cardiology Lab, IRCCS L. Spallanzani, Rome, Italy., Lambiase A; Department of Sense Organs, Sapienza University of Rome, Rome, Italy., Conti F; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Garibaldi M; Department of Neuroscience, Mental Health, and Sensory Organs (NESMOS), Sant'Andrea Hospital, Sapienza University, Rome, Italy., Inghilleri M; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy., Ceccanti M; Department of Human Neuroscience, Centre for Rare Neuromuscular Disease, Sapienza University of Rome, Rome, Italy.

Publikováno v: Current neuropharmacology [Curr Neuropharmacol] 2023; Vol. 21 (12), pp. 2543-2549.